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Background: Perfluoroalkyl substances (PFAS) are suggested to affect human fecundity through longer time to pregnancy (TTP). We studied the relationship between four abundant PFAS and TTP in pregnant women from Greenland, Poland and Ukraine representing varying PFAS exposures and pregnancy planning behaviors. Methods: We measured serum levels of perfluorooctanoic acid (PFOA), perfluorooctane sulfo
Possibilities to develop human monoclonal antibody specificities have recently been much facilitated by improvements of human hybridoma technology but even more so by the emerging phage-display technique. However, until recently very little has been known about the characteristics at the molecular level of the induced, T cell-dependent human antibody response, frequently targeted by these techniqu
Background: Musculoskeletal pain is among the most common reasons for seeking care, specialist competence for its treatment in primary care limited and waiting lists for orthopaedics often amongst the longest. Many referrals to orthopaedics do not concern disorders that benefit from surgery. Manual therapy is effective, yet not integrated in national health care systems, and there is a lack of res
Context. The star HD 139139 (a.k.a. ‘the Random Transiter’) is a star that exhibited enigmatic transit-like features with no apparent periodicity in K2 data. The shallow depth of the events (-200 ppm - equivalent to transiting objects with radii of -1.5 R⊕ in front of a Sun-like star) and their non-periodicity constitute a challenge for the photometric follow-up of this star. Aims. The goal of thi
People with a refugee background are at significantly increased risk of mental health difficulties, including Post-Traumatic Stress Disorder (PTSD). There is a large evidence base showing that trauma-focused psychological treatments for PTSD are effective. However, the majority of trials do not include refugees and less is known about how refugees respond to treatment. The present report explores
BACKGROUND: Trigger finger surgery typically has a successful outcome, also in patients with diabetes mellitus (DM). However, the impact of glycemic control on long-term outcomes after open trigger finger release (OTFR) remains unclear. This study examines whether high hemoglobin A1c (HbA1c) levels affect patient-reported outcome (PRO) following OTFR in individuals with type 1 diabetes mellitus (T
Background: Despite several decades of experience with atrial pacing, many centers do not apply this mode to any greater extent, mainly because of concerns for the development of future atrioventricular (AV) block or atrial fibrillation. Recent studies have emphasized possible negative effects of right ventricular stimulation, even when AV-synchrony is preserved, and have thus given rise to renewe
Study Design. Observational cohort study. Objective. To evaluate by MRI whether a vertebral fracture during childhood is a risk factor for degeneration of adjacent discs. Summary of Background Data. Several studies infer that trauma is a major cause of disc degeneration. Only 1 study has by magnetic resonance imaging (MRI) evaluated disc degeneration in children with a former thoracic or lumbar ve
The European Association of Urology Renal Cell Carcinoma (RCC) guidelines panel updated their recommendation on adjuvant therapy in unfavourable, clinically nonmetastatic RCC following the recently reported results of a second randomised controlled phase 3 trial comparing 1-yr sunitinib to placebo for high-risk RCC after nephrectomy (S-TRAC). On the basis of conflicting results from the two availa
The use of 18S rDNA sequences for inferring phylogenies, in particular for higher taxonomic level analysis, has a long tradition in phycology. Similar to ITS2, the 18S rDNA displays a conserved secondary structure that could be used simultaneously with the primary sequence to increase the amount of information used when inferring phylogenetic relationships. Sequence-structure phylogenetics is alre
STUDY DESIGN: Observational cohort study. OBJECTIVE: To evaluate by MRI whether a vertebral fracture during childhood is a risk factor for degeneration of adjacent discs. SUMMARY OF BACKGROUND DATA: Several studies infer that trauma is a major cause of disc degeneration. Only 1 study has by magnetic resonance imaging (MRI) evaluated disc degeneration in children with a former thoracic or lumbar ve
This doctoral thesis is comprised of five parts which deal with different signal processing problems in ECG-based characterization of atrial arrhythmias. Such characterization requires that the ventricular activity has first been cancelled in the ECG. In Part I, a new method for cancellation of the QRST complexes in recordings with atrial fibrillation is presented. The method is based on a spatiot
Intellectual property rights easily come in conflict with the objectives of the EC Treaty since they are exclusive in their nature and can be seen as a legal way to create trade barriers. In Article 222 of the Treaty it is stated that the Treaty shall not prejudice the rules in the Member States governing the system of property ownership, and in Article 36 it is permitted to protect intellectual p
This paper describes a factor analysis applied at the data of the European Union structural indicators. These are the official indicators for wealth and economic development in the European Union with main use to evaluate the outcomes of the year 2000 Lisbon goals for making the European Union the world’s strongest economy by 2010. The purpose of the data is to serve for comparing and “learning by
The need of a European immigration policy within the EU appear to be evident. Until fairly recently, immigration and asylum policy was strictly the concern of every national state but since the mid-80s, a clear intensification of cooperation has taken place. The measures taken in this field the last 15 years have been concentrated on exclusion of foreigners. The Single European Act introduced an a
Skadestånd vid offentlig upphandling är ett relativt outforskat område i svensk rätt och upphandlingens unika karaktär gör att det inte är möjligt att rakt av plocka lösningar från den övriga skadeståndsrätten. Den här uppsatsen syftar till att utreda upphandlingsskadeståndets karaktär i förhållande till den övriga skadeståndsrätten, dock begränsat till ansvaret för ren förmögenhetsskada i utomoblDamages in public procurement is a relatively unexplored area in Swedish law and the special nature of the procurement procedure means that it is not possible to solve certain issues by looking solely at the established tort law. This paper aims to investigate the character of the liability to pay damages in relation to the rest of the tort law; however, it is limited to the liability for damages
Bostadsmarknaden har under en längre tid kantats av ett antal problem både på ägande- och hyresmarknaden. Majoriteten av landets kommuner rapporterar en rådande bostadsbrist och effektivitetsförlusten till följd av efterfrågeöverskottet beräknas till 10 miljarder kronor per år. Identifierade problem på bostadsmarknaden är avsaknaden av fungerande flyttkedjor, långa bostadsköer, höga bostadspriser The Swedish housing market has been pressured for a long time with a majority of Swedish municipalities reporting housing shortages. The efficiency loss due to unmet demand is estimated at 10 billion SEK annually. Identified obstacles on the housing market are lack of functioning vacancy chains, long housing queues, high prices and constraining legislation. In 2009, new legislation was introduced
The rules of responsibility regarding the working enviroment during the production in the construction industy makes it hard to demand responsibility when accidents occur even when there are flaws in the working enviroment. Flaws in the working enviroment is a big problem on construction sites and there are alot of accidents but at the same time only a few lead to conviction. The way cnstruction s
This study examines the long-term abnormal returns of stocks following Initial Public Offerings (IPOs) and Seasoned Equity Offerings (SEOs) on the Swedish and American markets from January 2000 to March 2021. Additionally, it examines the differences between Swedish and American companies and investigates factors influencing these disparities, focusing on the importance of market capitalization at
