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One of the most common methods of inducing stress in the laboratory in order to examine the stress response in healthy and clinical populations is the Trier Social Stress Test (TSST). Briefly, the participant is asked to deliver a speech and to perform an arithmetic task in front of an evaluating committee. The committee, consisting of three trained actors, does not respond emotionally during the
The aim of this study was to determine in patients with HCV genotype 2 or 3 the performance at week 4 of two assays with different sensitivities for HCV RNA detection, for the prediction of SVR and stratification for treatment duration (14 and 24 weeks). Recruitment was from two trials comparing 14 and 24 weeks treatment to patients with rapid virological response (RVR) (n = 550). RVR was original
The DyDOC model simulates the C dynamics of forest soils, including the production and transport of dissolved organic matter (DOM), on the basis of soil hydrology, metabolic processes, and sorption reactions. The model recognizes three main pools of soil C: litter, substrate (an intermediate transformation product), and humic substances. The model was used to simulate the behavior of C in the 0 ho
Human alpha 1-microglobulin (alpha 1-m), a 26 kilodalton serum glycoprotein, was found to exert mitogenic effects on human peripheral blood lymphocytes (PBL) in serum-free medium. Purified T cells, but not B cells, responded with proliferation to alpha 1-m, but only in the presence of monocytes. The mitogenic activity could be partially neutralized by a mouse monoclonal antibody against alpha 1-m.
Introduction: Medical treatment of women with idiopathic recurrent pregnancy loss is controversial. The objective was to assess the effects of different treatments on live birth rates and complications in women with unexplained recurrent pregnancy loss. Material and methods: We searched MEDLINE, Embase and the Cochrane Library, and identified 1415 publications. This systematic review included 21 r
It is difficult to overstate the importance of the concept sovereignty for international relations (IR). And yet, understanding the historical emergence of sovereignty in international relations has long been curtailed by the all-encompassing myth of the Peace of Westphalia. While criticism of this myth has opened space for further historical inquiry in recent years, it has also raised important q
Is there a universal hierarchy of the senses, such that some senses (e.g., vision) are more accessible to consciousness and linguistic description than others (e.g., smell)? The long-standing presumption in Western thought has been that vision and audition are more objective than the other senses, serving as the basis of knowledge and understanding, whereas touch, taste, and smell are crude and of
The Law of Carriage of Goods by Sea is dominated by international conventions. Both Sweden and England have one of these conventions, the Hague-Visby Rules (HVR), as the basis for their mandatory legislation. Accordingly, the relationship between the parties to a contract of carriage by sea is generally regulated in similar ways in these two countries. The new Swedish Maritime Code from 1994 has t
Diabetic kidney disease, or diabetic nephropathy (DN), is a major complication of diabetes and the leading cause of end-stage renal disease (ESRD) that requires dialysis treatment or kidney transplantation. In addition to the decrease in the quality of life, DN accounts for a large proportion of the excess mortality associated with type 1 diabetes (T1D). Whereas the degree of glycemia plays a pivo
Organizational resource acquisition including finance and people in a dynamic environment affects the venture’s business activities and even its establishment. This paper aims to examine the concept mass customization and the process of obtaining resource commitments for the creation of a new venture called D.B.M. in the face of liabilities of newness. To this end, a case study based on the first-
Evidence suggests an influence of sex hormones on cutaneous melanoma risk, but epidemiologic findings are conflicting. We examined the associations between use of oral contraceptives (OCs) and menopausal hormone therapy (MHT) and melanoma risk in women participating in the European Prospective Investigation into Cancer and Nutrition (EPIC). EPIC is a prospective cohort study initiated in 1992 in 1
Background & Aims The risk of hepatocellular carcinoma (HCC) in primary sclerosing cholangitis (PSC) is unclear. Studies indicate a low risk for HCC questioning the rationale for current HCC surveillance guidelines. This study explores the risk of HCC in a longitudinal multicenter cohort with over 3.000 PSC-subjects. Approach & results Subjects with well characterized PSC (n=3.071) were fo
Context. Aims. The goal of this paper is to demonstrate the outstanding quality of the second data release of the Gaia mission and its power for constraining many different aspects of the dynamics of the satellites of the Milky Way. We focus here on determining the proper motions of 75 Galactic globular clusters, nine dwarf spheroidal galaxies, one ultra-faint system,
Purpose: To assess the association between cystatin C-derived estimates of kidney function and mortality and acute kidney injury (AKI) in sepsis. Materials and methods: Post-hoc analysis of sepsis patients in the FINNAKI-cohort (n = 802). Primary outcome was 90-day mortality. We measured plasma cystatin C and creatinine at intensive care unit (ICU) admission and estimated glomerular filtration rat
Background and purpose — Reduced range of motion (ROM) and spasticity are common secondary findings in cerebral palsy (CP) affecting gait, positioning, and everyday functioning. These impairments can change over time and lead to various needs for intervention. The aim of this study was to analyze the development path of the changes in hamstring length, knee extension, ankle dorsiflexion, and spast
PURPOSE: To compare agreement of corneal epithelium thickness (ET) between AS-OCT system (RTVue, Optovue) and AS-OCT/Placido topographer (MS-39, CSO) in eyes with different stages of keratoconus (KC), and to assess the repeatability of RTVue AS-OCT. DESIGN: Prospective reliability analysis. METHODS: KC eyes were classified into forme fruste KC (FFKC), mild, moderate, and severe KC. Agreement was e
The marine environment, contains plentiful renewable resources, e.g. macroalgae with unique polysaccharides, motivating search for enzymes from marine microorganisms to explore conversion possibilities of the polysaccharides. In this study, the first GH17 glucanosyltransglycosylase, MlGH17B, from a marine bacterium (Muricauda lutaonensis), was characterized. The enzyme was moderately thermostable
Histatins are a family of human salivary peptides which act as a part of the innate immune system. There are three main members of the family: Histatin 1 (Hst1), Histatin 3 (Hst3), and Histatin 5 (Hst5). Histatins have long been known to possess differing antimicrobial properties, such as antifungal and antiviral capabilities. Hst5 is generally described as the most potent antifungal peptide in th
I den här studien har jag tittat på upplevelser från personer som inte känner sig inkluderade eller välkomna i ideella organisationer i Malmö som arbetar för ett mer demokratiskt samhälle. Detta har jag gjort genom att analysera intervjuer med dessa personer samt två andra organisationer genom min metod tematisk innehållsanalys utifrån min teori intersektionell feminism. Studien är placerad i MalmTo create inclusion in non-governmental organizations - A study based on people’s experiences on exclusion. In this study have I looked at the experience of people who do not feel included nor welcome in non-governmental organizations in Malmö who works towards a more democratic society. I have done this through analyzing interviews with these people as well as two other organizations through my
The climate crisis in one of the major challenges of our time. The role of trade in this context is a contested issue, both good and bad effects are plausible. One important question in this context is whether it is possible to increase the chance that trade does not have a negative impact on the environment by including environmental provisions in trade agreements. While this might be possible, i
