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It is unknown whether the risk factor profile for mesenteric venous thrombosis (MVT) is different from systemic venous thromboembolism (VTE). The aim of the present population-based study was to compare acquired and inherited risk factors in MVT versus VTE. Identification of all MVT patients at Skåne University Hospital between 2000 and 2015 was performed in patient records and AuriculA (Swedish a

Conservation programmes for endangered, long-lived and migratory species often have to target multiple life stages. The bottlenecks associated with the survival of juvenile anguillid eels migrating into inland waters, the survival and growth of the freshwater life stage, as well as the recruitment and survival of silver eels, migrating back to the ocean to spawn, must be resolved. In this study, w

Background Hyper-CVAD is widely used to treat acute lymphoblastic leukemia (ALL) and aggressive lymphomas. This multicenter, population-based study assessed the efficacy of Hyper-CVAD as first-line therapy in patients with T-cell ALL (T-ALL). Patients and methods Between October 2002 and September 2006, 24 patients were diagnosed with T-ALL in Sweden; 19 were eligible for treatment with the protoc

BACKGROUND: Reduced forced expiratory volume (FEV(1)) and forced vital capacity (FVC) are risk factors for myocardial infarction (MI) and stroke. However, the relationship with incidence of heart failure (HF) is incompletely known. This population-based study explored whether reduced FEV(1) or FVC is associated with the incidence of hospitalisation for HF. METHODS: 20 998 men (mean age 43 years) w

Objective: To explore the use and interpretation of self reported on/off diary data for assessment of daily motor fluctuations in Parkinson’s disease. Methods: 26 consecutive non-demented patients with fluctuating Parkinson’s disease received standardised training on how to fill out the four category CAPSIT-PD on/off diary, followed by four hours of clinical observation and four weeks of daytime

Here we studied the effects of glial cell line-derived neurotrophic factor (GDNF) in a rat model that represents the symptomatic stages of Parkinson's disease. GDNF was infused starting 2 weeks after an intrastriatal 6-hydroxydopamine (6-OHDA) lesion in order to halt the ongoing degeneration of the nigrostriatal dopaminergic neurons. GDNF or vehicle was infused in the striatum or the lateral ventr

Högsta domstolen har i rättsfallet ”Låneavtalet med 4Finance” – NJA 2017 s. 1105 prövat frågan om bevisbördans placering i en situation då innehavaren av en avancerad elektronisk underskrift invände att underskriften hade använts obehörigen av en annan person för att underteckna en elektronisk låneförbindelse. Uppsatsens syfte är att klarlägga och ge förståelse för den aktuella bevisbörderegeln. UIn the court case NJA 2017 p. 1105, the Swedish Supreme Court has considered the question of the placement of the burden of proof in a situation where the holder of an advanced electronic signature objected that the signature had been used unauthorizedly by another person to sign an electronic loan commitment. The purpose of the essay is to clarify and provide an understanding of the current burde

Under de senaste åren har det uppkommit ett fåtal fall där foster/barn uppvisar livstecken eller livsduglighet vid sen abort. Det har medfört en diskussion, såväl etisk som rättslig, avseende hälso- och sjukvårdspersonalens agerande i den uppstådda situationen. En del anser att hälso- och sjukvårdspersonal bör ge foster/barn den vård som krävs med syfte att foster/barn ska överleva. Detta motiveraDuring the last couple of years, there have been a few cases where foetuses/children show signs of life or viability after late abortion. This has led to a discussion ethical and legally, regarding the actions of the healthcare professionals towards the fetus/child. Some argue that healthcare professionals should provide the foetuses/children with the necessary care for the foetuses/children to su

Archivists tackle a variety of problems in their daily work, among them are issues concerning privacy-based material. This work demands a good understanding of the laws which govern this practice, laws comprising the Freedom of the Press Act (tryckfrihetsförordningen SFS 1949:105), the Public Access and Security Act (offentlighets- och sekretsslagen SFS 2009:400), and the Archival Law (arkivlagen

Lojalitet är en viktig beståndsdel i alla komplexare IT-outsourcingprojekt. I ett outsourcingförhållande där parterna inte agerar lojalt mot varandra kan relationen dem emellan störas vilket i sin tur kan leda till stora kostnader. Vested är en amerikansk modell för bl.a. komplexare outsourcingförfaranden i vilken lojaliteten mellan parterna särskilt betonas. Vested-modellen är ännu relativt oanväLoyalty is an important feature in a complex IT-outsourcing, without it the relationship will deteriorate eventually resulting in economic loss for both parties. Vested is an American loyalty centered cooperation model designed to be applied on complex outsourcing procedures. Vested is still relatively unknown in Sweden today, but the model can be predicted to surge in popularity in the future. T

Vid entreprenadprojekt uppkommer ofta tvister rörande entreprenörens rätt till tidsförlängning och ersättning för merkostnader. Vid sådana tvister kan det vara svårt för entreprenören att visa vad som har orsakat den händelse som entreprenören menar ger rätt till tidsförlängning eller ersättning, och hur stort behovet av tidsförlängning eller merkostnader är. Dessa svårigheter har lett till utveckIn construction projects it often arise disputes concerning the contractor’s right to an extension of time and compensation for extra costs. In these disputes it can be challenging for the contractor to prove what has caused the effect that the contractor consider entitle to extension of time or compensation for extra costs, and how great the need for an extension of time or extra costs are. Such

Denna uppsats syftar till att undersöka om en återinförd revisionsplikt för små aktiebolag är en effektiv och proportionerlig åtgärd för att motverka att aktiebolag används för att begå brott. År 2010 avskaffades generell revisionsplikt i Sverige. En generell revisionsplikt innebär att samtliga aktiebolag är skyldiga att ha minst en revisor. I stället infördes vissa gränsvärden som stadgar när revThis thesis aims to examine whether reinstating an audit obligation for small limited companies is an effective and proportionate measure to counteract economic crime. In 2010, audit obligation for all limited companies was abolished in Sweden. Instead, certain thresholds were established that stipulate when an audit obligation arises. Today, audit is obligatory only if the company, for two consec

Budgerigars (Melopsittacus undulatus) and Bourke's parrots (Neopsephotus bourkii) are closely related birds with different activity patterns. Budgerigars are strictly diurnal while Bourke's parrots are active in dim twilight. Earlier studies show that the intensity threshold of colour vision is similar in both species while Bourke's parrots have larger eyes with a higher density of rods than budge

OBJECTIVES: This study evaluated the long-term risk of permanent pacemaker implantation following Cox-maze IV (CMIV) and concurrent mitral valve surgery. METHODS: A retrospective, nationwide, registry-based analysis was conducted on postoperative permanent pacemaker implantation in 397 patients with symptomatic mitral valve insufficiency and atrial fibrillation who underwent CMIV and mitral valve

Background: Tattoo inks are mixtures of organic and inorganic color pigments and having a tattoo may be adversely associated with biomarkers of male fecundity. Objective: To examine the association between tattoo exposure and biomarkers of male fecundity. Methods: Participants were young adult Danish males (aged 18–21 years) sampled from the Danish National Birth Cohort. Upon recruitment in 2017–2

BACKGROUND: Many poly- and perfluoroalkyl substances (PFAS) are persistent and have long half-lives in the human body. However, there are limited data on the different routes of elimination. Most pharmacokinetic models assume that the urinary route dominates.OBJECTIVES: Our aim was to investigate the relative importance of fecal and urinary elimination for linear perfluorooctane sulfonic acid (L-P

OBJECTIVES: To investigate hip dysplasia as a risk factor for clinically relevant and incident radiographic hip OA.METHODS: From a prospective cohort (CHECK) of 1002 middle-aged, new consulters for hip and/or knee pain, 468 hips (251 individuals) were selected based on hip pain, available lateral center edge angle (LCEA) and absence of definite radiographic hip OA (Kellgren and Lawrence [KL] grade

Mitochondrial dysfunction is associated with pathogenic mitochondrial (mt)DNA mutations. The majority of mtDNA point mutations have a heteroplasmic status, which is defined as the coexistence of wild-type and mutated DNA within a cell or tissue. Previous findings demonstrated that certain mtDNA heteroplasmic mutations contribute to widely spread chronic diseases, including cancer, and alterations

Introduction: Tumor deposits are an important negative prognostic factor for long-term oncological outcomes in colorectal cancer patients, independent of lymph node status. Several novel models have been proposed to further integrate tumor deposits into the TNM-staging system, but their comparative performance remains unclear. The aim of this study was to identify, compare and validate novel progn