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Protein kinase C (PKC) plays a prominent role in immune signaling, and the paradigms for isoform selective signaling are beginning to be elucidated. Real-time microscopy was combined with molecular and biochemical approaches to demonstrate a role for PKC-epsilon in Fcgamma receptor (FcgammaR)-dependent phagocytosis. RAW 264.7 macrophages were transfected with GFP-conjugated PKC isoforms, and GFP m
Immunoglobulin G (IgG) glycosylation modulates antibody activity and represents a major source of heterogeneity within antibody preparations. Depending on their glycosylation pattern, individual IgG glycovariants present in recombinant antibody preparations may trigger effects ranging from enhanced pro-inflammatory activity to increased anti-inflammatory activity. In contrast, reduction of IgG gly
OBJECTIVE: To investigate the possible role of FCGR2A 519A>G and FCGR3A 559A>C functional polymorphisms in the genetic predisposition to susceptibility to systemic sclerosis (SSc) or clinical phenotype. METHODS: A total of 1566 patients with SSc and 2271 geographically matched controls were included in our study. We analyzed the genotype and allele frequencies of the FCGR2A 519A>G and FCGR3A 559A>
Clay as a craft material has fascinated me for a long time. It is a very versatile material that can be so smooth and ductile but also, after firing, extremely hard and strong. Why is this material, with all its characteristics not used as an architectural material more often? I started looking at ceramic materials in architecture and found that they are somewhat related to the act of waiting. In
Examensarbetet är utfört på och i samarbete med Imtech Ventilation i Malmö. Författarens avsikt har från början varit att skapa något som kan vara till stor nytta för företaget. Därför har examensarbetet utförts i nära samarbete med Imtech Ventilations medarbetare. Författaren har gjort en bakgrundsanalys av energikravs-läget i byggbranchen. Detta för att ta fram en validerad problemformulering oc
Summary – 200 words In education today, there is a paradigm shift with critical challenges for Universities to enhance innovation in teaching and learning. Knowledge and learning are critical issues for most companies and private and civil service organizations with today’s rapid changes in socio-economy and technology. The needs for competence development vary along a broad scale from short info
Under the current accounting systems, emissions produced when biomass is burnt for energy are accounted as zero, resulting in what is referred to as the 'carbon neutrality' assumption. However, if current harvest levels are increased to produce more bioenergy, carbon that would have been stored in the biosphere might be instead released in the atmosphere. This study utilizes a comparative approach
Ever since the nation-state has existed identity has been a big deal, it is told that identity is a tool needed to be able to receive consensus from the people concerned on a certain matter. As the European Union is continuously shaped and reshaped due to changing geographical borders, as a consequence of new member-states the aim to integrate the Union equally across its surface has not been an e
Introduction The incidence of perforated peptic ulcer remains high in low and middle-income countries. Mortality can be significant, and early surgical management with careful evaluation of pre-operative risk factors is essential. The purpose of this study was to describe the clinical outcomes of surgical treatment for perforated peptic ulcer disease in Liberia and to explore risk factors for adve
This interdisciplinary course will introduce the climate-biodiversity-health nexus and consider Nature-Based Solutions through the lens of (environmental) psychology, ecology, and epidemiology. It will include both theoretical lectures and application of the knowledge in group work, group discussions, and a study visit to two Nature-Based Solutions in Skåne (Malmö and Hörby). You can contact marli
This article explores how quantitative organological analysis can be implemented alongside historical musicology to help stimulate creativity in performance practice while promoting a diversity of timbre that is often lost amidst the hegemonic propagation of homogenized, normalized modern musical instruments. The tuba family provides an insightful case study demonstrating how the history and devel
Bluvisions IoT-system har varit huvudfokus under utredningen av om IoT(Internet of Things) är lönsamt att implementera på framtidens Valmetmaskiner. Från början så skulle projektet avgränsas till pressning, kräppning och upprullning men under examensarbetets start fick Valmet svårt att hitta orsaken till varför en ny komponent hade havererat. Havereringen tros ha haft ett samband med höga vibratio
