Search results

While several scholars do not consider the anointing of (the feet of) Jesus in Bethany described in the Gospel of John to carry any messianic connotations, some claim that a royal messianic notion is behind the anointing. The hypothesis of this paper is that the anointing is indeed to be understood as messianic, but that it is insufficient to consider only one Christological motif to be in the bac

EF-hand proteins are central in many cellular processes being the main group of Ca2+-sensing and buffering proteins in the cell. In the work presented in this thesis we study ligand interactions of three EF-hand proteins; calmodulin, calbindin D28k and secretagogin. We have developed a screening method using proteins arrays and validation of targets with surface plasmon resonance. With have applie

Exaggerated acidosis due to preischemic hyperglycemia shortens the maturation time for cell death and turns selective neuronal damage into pannecrosis. Some issues concerning the mechanisms are yet to be clarified. The present study was designed to define critical thresholds of plasma glucose, to investigate the influence of preischemic hyperglycemia on ion transients, to evaluate the role of calc

The enzyme ferrochelatase (EC 4.99.1.1) is the terminal enzyme in the biosynthetic pathway of heme b and catalyzes the insertion of Fe(II) into protoporphyrin IX. In this dissertation ferrochelatase from Bacillus subtilis was studied. A new purification method via inclusion bodies was developed that enabled simple purification of recombinant enzyme without tags or modifications that might affect t

Prostate-specific antigen (PSA) and human prostatic glandular kallikrein (hK2) have 79% identity with the primary structure. When we used recombinant hK2 protein, only 7 of 23 monoclonal anti-PSA IgGs (monoclonal antibodies, MAbs) cross-reacted with hK2, which enabled us to design a novel immunofluorometric MAb-MAb assay for the specific detection of hK2. In the first incubation, an excess of MAb

Bacterioplankton respiration (BR) may represent the largest single sink of organic carbon in the biosphere and constitutes an important driver of atmospheric carbon dioxide (CO2) emissions from freshwaters. Complete understanding of BR is precluded by the fact that most studies need to assume a respiratory quotient (RQ; mole of CO2 produced per mole of O-2 consumed) to calculate rates of BR. Many

Knowing the natural dynamics of pathogens in migratory birds is important, for example, to understand the factors that influence the transport of pathogens to and their transmission in new geographical areas, whereas the transmission of other pathogens might be restricted to a specific area. We studied haemosporidian blood parasites of the genera Plasmodium, Haemoproteus and Leucocytozoon in a mig

Cutaneous human papillomaviruses (HPVs) have been associated with squamous cell carcinoma (SCC) in case-control studies, but there are limited data from prospective studies assessing whether virus exposure predicts risk of future cancer development. Two major biobanks, the Southern Sweden Microbiology Biobank (1971-2003) and the Janus Biobank (1973-2003) in Norway, containing samples from 850,000

Traumatic brain injury (TBI) is one of the leading causes of death in children worldwide. Emerging evidence suggests that alterations in mitochondrial function are critical components of secondary injury cascade initiated by TBI that propogates neurodegeneration and limits neuroregeneration. Unfortunately, there is very little known about the cerebral mitochondrial bioenergetic response from the i

Specific motor symptoms of Parkinson's disease (PD) can be treated effectively with direct electrical stimulation of deep nuclei in the brain. However, this is an invasive procedure, and the fraction of eligible patients is rather low according to currently used criteria. Spinal cord stimulation (SCS), a minimally invasive method, has more recently been proposed as a therapeutic approach to allevi

The aim of this study was to examine whether small biopsy specimens are representative of the whole human skeletal muscle or whether the different fibre types are unevenly distributed at different depths of the muscle. Ten micrometre thick cross-sections of whole human tibialis anterior were prepared using LKB PMV Cryo-Microtomes with a stroke length of 160 to 480 mm and the sections were stained

From the Management This week the management group continued the work regarding the assignment from the Faculty, that will be presented on the Friday Fika on 11 June. There were also preparations for the yearly dialogues with the Faculty, that are due in September. Covid-19 update The vice-chancellor of Lund University has taken a new decision on Covid regulations. In short, the same regulations c

https://www.cec.lu.se/staff-pages/staff-newsletters/20-may-2021 - 2026-07-13

Amidst a surge in global demand for materials driving the green transition, this thesis investigates how policymakers can best ensure sound environmental performance in the Swedish mining industry following unexpected mine closures. Current Swedish financial assurance mechanisms, intended to operationalize the Polluter Pays Principle, are hampered by unclear criteria and a focus on individual site

When user interfaces are embedded in physical systems and cannot be accessed through conventional screen sharing, remote usability testing becomes challenging. This is increasingly relevant as products are developed for global markets, where remote evaluation is often necessary despite limited user interface access. This study investigates how alternative testing methods can be used and how they i

Understanding the role of conformational entropy in protein-ligand interactions remains a major challenge in rational drug design. In this work Galectin-3C (Gal-3C) complexes with glycomimetic macrocyclic ligands FS435 and FS471 were investigated using NMR spectroscopy. The ligands exhibit similar binding free energies, and calorimetric studies revealed significant enthalpy-entropy compensation. S

Title: When the Map Is Wet, Navigation Still Depends on It: Organizational Sensemaking and Digital Infrastructure Dependency Course: BUSN49, Degree Project in Managing People, Knowledge and Change – Master Level Authors: Clara Gerber and Ember Truppelli Supervisor: John Murray Purpose: This study examines how individuals within organizations make sense of digital infrastructure dependency when the

The JPL rover Perseverance's investigations of Jezero crater's floor reveal that the ultramafic Séítah formation and the overlying mafic Máaz formation are deformed into a broad, low-amplitude structural dome. Mastcam-Z stereo images processed into digital outcrop models, together with RIMFAX ground-penetrating radar profiles, were used to reconstruct the three-dimensional stratal geometry of both

Companies continuously seek to improve both operational efficiency and financial performance. To support operations and enable investments, capital is required. An important consideration is capital binding, which refers to the amount of capital tied up within the business and the duration for which it remains tied up. While capital binding is often associated with inventory levels, it emerges thr