Filetype
We analysed the reason for knee pain after intramedullary (IM) nailing with standard MRI sequences at a mean of 27 months (range 2-45) after nail removal in eleven patients with a mean age of 30 years (range 15-52). Knee pain was assessed in four grades. All our patients had signal changes of fluid in the nail channel, areas of low signal intensity in Hoffa's fat pad and subcutaneous low signal no
Intergovernmental Panel on Climate Change (IPCC) Tier 1 methodologies commonly underpin project-scale carbon accounting for changes in land use and management and are used in frameworks for Life Cycle Assessment and carbon footprinting of food and energy crops. These methodologies were intended for use at large spatial scales. This can introduce error in predictions at finer spatial scales. There
The Swedish Twin Registry (STR) today contains more than 194,000 twins and more than 75,000 pairs have zygosity determined by an intra-pair similarity algorithm, DNA, or by being of opposite sex. Of these, approximately 20,000, 25,000, and 30,000 pairs are monozygotic, same-sex dizygotic, and opposite-sex dizygotic pairs, respectively. Since its establishment in the late 1950s, the STR has been an
The present study focuses on fragmented deglycosylated pyranose dehydrogenase (fdgPDH) from Agaricus meleagris recombinantly expressed in Pichia pastoris. Fragmented deglycosylated PDH is formed from the deglycosylated enzyme (dgPDH) when it spontaneously loses a C-terminal fragment when stored in a buffer solution at 4 degrees C. The remaining larger fragment has a molecular weight of similar to
A precise U-Pb baddeleyite age of 2733 +/- 2 Ma has been obtained for the Ahmeyim Great Dyke of Mauritania that intruded into the Tasiast-Tijirit Terrane of the Reguibat Shield, NW Mauritania. This dyke is approximately 1500 m wide at the sampling area and extends for more than 150 km NNE/SSW. Major and trace element geochemistry of the dyke indicates that the magmas that formed this intrusive bod
The massive amount of genomic sequence data that is now available for analyzing evolutionary relationships among 31 placental mammals reduces the stochastic error in phylogenetic analyses to virtually zero. One would expect that this would make it possible to finally resolve controversial branches in the placental mammalian tree. We analyzed a 2,863,797 nucleotide-long alignment (3,364 genes) from
The disease mechanisms underlying type 2 diabetes (T2D) remain poorly defined. Here we aimed to explore the pathophysiology of T2D by analyzing gene co-expression networks in human islets. Using partial correlation networks we identified a group of co-expressed genes ('module') including F2RL2 that was associated with glycated hemoglobin. F2Rl2 is a G-protein-coupled receptor (GPCR) that encodes p
Energy is typically a limiting factor for animals during boreal zone winters, when low temperatures increase the cost of thermoregulation at the same times as short day-lengths and snow cover constrain foraging opportunities. Under these circumstances animals use a suite of behavioural and physiological adaptations to avoid overnight starvation. However, it is poorly understood how such strategies
BackgroundPost-relapse survival (PRS) was evaluated in patients with Ewing sarcoma (EWS) enrolled in chemotherapy protocols based on the use of high-dose chemotherapy with busulfan and melfalan (HDT) as a first-line consolidation treatment in high-risk patients. ProcedureEWS patients enrolled in ISG/SSG III and IV trials who relapsed after complete remission were included in the analysis. At recur
Popular Abstract in Swedish I denna studie har de grundläggande aspekterna på mass- och värmetransport i membrantekniken pervaporation studerats. Speciell tonvikt har lagts vid pervaporations användbarhet i samband med aromämnesåtervinning. Masstransporten i pervaporation påverkas av ett yttre masstransport- motstånd kallat koncentrationpolarisation. Detta fenomen kan orsaka att fluxen av de seleIn this study, the fundamental mass and heat transfer properties of the membrane separation process called pervaporation were investigated. The suitability of pervaporation for aroma compound recovery was especially evaluated. The mass transfer in pervaporation is affected by an external mass transfer resistance in the liquid feed boundary layer, i.e. the concentration polarization phenomenon. Th
Ultrafast accelerator-based sources combined with synchronized femtosecond lasers are currently being developed. The method described here is intended as a jitter monitor at such facilities. We report on the possibility of extracting a time-offset signal between two different synchronized ultrashort light pulses. The method is based on sum-frequency generation in a nonlinear crystal. Aiming at ext
Objective. To investigate whether measurements of proinsulin and/or intermediate proinsulin degradation products could be used to differentiate between autoimmune (type 1) and non-autoimmune (type 2) diabetes in young adults. Material and methods. Total proinsulin, intact proinsulin and 32,33 split proinsulin concentrations were measured in 25 patients aged 15-34 years with type 1 diabetes, as def
The title compound, [ Pt( NO3)(2)( C2H6S)(2)], crystallizes in the P2(1)/ n space group ( Z' = 2), with pseudo- square- planar coordination geometry. The complex forms dimers with pseudosymmetry C-i arranged in columns along the b- axis direction, with Pt center dot center dot center dot Pt distances of 6.3056 ( 3) and 4.2382 ( 2) angstrom ( at 150 K). Each column is surrounded by six other column
Streptococcus pneumoniae (pneumococcus) is a pathogen that causes severe local and life-threatening invasive diseases, which are associated with high mortality rates. Pneumococci have evolved several strategies to evade the host immune system, including complement to disseminate and to survive in various host niches. Thus, pneumococci bind complement inhibitors such as C4b-binding protein (C4BP) a
The thesis concerns experimental studies of bubble motion and the transport of large particles and bubbles. Bubbly flows are encountered in many engineering applications where the bubbles play an important role for the mass transfer between the phases, e.g. in stirred reactors. A special case of bubble transport is the cavitation phenomenon, which mainly has a negative effect on the performance of
Popular Abstract in Swedish Spridning och inavel i naturen I modern tid har vi människor orsakat stora förändringar i miljön, vilket påverkat många arters livsbetingelser. Exempelvis har vi avskogat stora områden och efterlämnat små delar av de större områden som tidigare hängde ihop. Organismer som lever i sådana uppsplittrade miljöer kommer att vara isolerade från varandra, vilket får som följdTo evaluate how inbreeding affects the viability of small populations, it is crucial to determine what constitutes a population (i.e., the number of breeders in local patches and the degree of dispersal), and also to estimate the reproductive consequences of philopatry and emigration. In this thesis, I concentrate on dispersal, inbreeding and fitness in natural populations. I consider dispersal ra
The human genome, in common with all mammalian genomes, carries a high load of inheritable retroviral sequences. We have identified and characterized a novel family of these endogenous retroviruses and have named this family HERV-F as based on the primer binding sites of three members. The HERV-Fs are C-type endogenous retroviruses that have unique gag, pol and env regions that are, based on phylo
Popular Abstract in Swedish Denna avhandling visar att jordgubbar innehåller ett allergen, proteinet Fra a 1, som är mycket likt det allergen som orsakar besvär vid björkpollen-allergi. Den som får allergiska besvär av jordgubbar, t.ex. att det kliar och blir irriterat i munhålan och svalget när man äter , har ofta en björkpollen-allergi sen tidigare. Motsvarande allergen finns också i en del andrStrawberry (Fragaria ananassa) is an economically important crop, and recognised as an important source of antioxidants and bioactive compounds with health promoting effects. Yet increased incidence of allergy puts a limit to the choice of food for an increasing percentage of the population. As part of this thesis a strawberry allergen termed Fra a 1 was identified, which is related to a major bi
Popular Abstract in Swedish Omgivningens temperatur är kanske en av de faktorer som i allra störst utsträckning påverkar djur och deras livsmiljö. Detta bottnar givetvis till stor del i temperaturens effekt på naturen. Betänk till exempel årstidsväxlingarna; att vintern blir till vår, och att hösten (i samband med de första snöfallen) allt mer skrider mot ännu en kall och vit vinter bestäms och reTemperature is a property of profound matter in all aspects of animal life, affecting both individual energy budgets and the environments in which animals reside. Thus, a proper understanding of the effects of temperature variation is instrumental in understanding not only animal form and function, but also the structure and dynamics of wild populations. Accordingly, the aims of this thesis were t
