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The dic(9;20)(p13.2;q11.2) is reported to be present in similar to 2% of childhood B-cell precursor acute lymphoblastic leukemia (BCP ALL). However, it easily escapes detection by G-banding analysis and its true prevalence is hence unknown. We performed interphase fluorescence in situ hybridization analyses-in a three-step manner-using probes for: (i) CDKN2A at 9p21, (ii) 20p and 20q subtelomeres
Digital controllers are traditionally implemented using periodic sampling, computation, and actuation events. As more control systems are implemented to share limited network and CPU bandwidth with other tasks, it is becoming increasingly attractive to use some form of event-based control instead, where precious events are used only when needed. Forms of event-based control have been used in prac
With the advent of multimodality therapy, the overall five-year survival rate from childhood cancer has improved considerably now exceeding 80% in developed European countries. This growing cohort of survivors, with many years of life ahead of them, has raised the necessity for knowledge concerning the risks of adverse long-term sequelae of the life-saving treatments in order to provide optimal sc
Det är vanligt att privatpersoner köper fordon på avbetalning med ett återtagande- och/ äganderättsförbehåll. I avbetalningskontraktet skrivs vanligtvis in att köparen ska teckna en motorfordonsförsäkring hos ett försäkringsbolag. Motsvarande gäller vid leasing av ett fordon, där det vanligtvis är leasingtagaren som ska teckna en motorfordonsförsäkring. Det finns några krav som försäkringstagaren It is common for individuals purchasing vehicles via hire purchase in a readmission and / retention of title. The installment contract is usually written so that the buyer must take out motor insurance with an insurance company. The same applies to the leasing of a vehicle, where it is the lessee who usually must take out motor insurance. There are requirement thus ensuring that the policyholder i
Under åren 1965-1974 genomfördes en omfattande bostadsproduktion i Sverige som betecknas miljonprogrammet. Då byggdes en miljon bostäder runtom i landet. Idag finns behov av att renovera dessa bostäder. I samband med det kan energisparåtgärder genomföras för att minska energianvändningen. Detta kan uppfyllas genom att åtgärda otäta väggar och byta ut äldre fönster som medför oönskade värmeförlusteIn order to maintain a good indoor environment, air pollutants such as moisture need to be removed by the ventilation. Among the Swedish Public Health Agency's general advices for ventilation and indoor environment, 3 g/m3 is a guideline value for moisture excess during winter months to not pose a risk to human health. The indoor climate parameters moisture excess, relative humidity and air va
This study aimed to determine the optimal method for extracting rosmarinic acid (RA) from lemon balm using pressurized liquid extraction (PLE). Additionally, the effect of filtration during sample preparation on the concentration of rosmarinic acid (RA) was investigated. Moreover, the RA content was compared in various lemon balm samples including: commercial dried lemon balm, commercial lemon bal
Infant mortality is a powerful indicator to measure the health and social status of a country. The purpose of this study is to identify the important factors that in uence the infant mortality of Bangladesh. Moreover, this study suggests the government and the policy makers to improve the health and social sectors for reducing the country's infant mortality signicantly. To investigate the impo
We present a parton-level phenomenological study of triple-Higgs production at leading order in proton-proton collisions at a center-of-mass energy of 100 TeV with an integrated luminosity of 30 ab^-1. This study aims to estimate the prospects for measuring the signal hhh production observable at the Future Circular Collider. We explore interesting final states that could be used for this purpose
The battle for Aleppo culminated in the year 2016 when Syrian regime forces captured northern parts of Aleppo making a siege a reality for many people. A question of who was to blame isn’t always clear when looking at complex conflicts. People often look towards media to make meaning of such complexities. This paper examines two different news organizations, RT and CNN, role in depicting perpetrat
Purchasing has become an increasingly important function in manufacturing companies, as it accounts for a large extent of total spending and influences a company's competitive position. It is relevant for Tetra Pak, a global manufacturer of packaging and processing solutions, active since the 1950s. Tetra Pak has over 100.000 active units at customers site over the world, to service them and o
The aim of this thesis is to examine how the production and consumption of milk in the modern and post-modern Swedish society can be said to reflect general cultural and societal development. Focus is put on how it is affected by notions of the cartesian dichotomy between nature and culture. This is achieved using literature drawing on several disciplines relevant to the interdisciplinary field of
Sverige har sedan länge ansetts vara ett land befriat från svågerpolitik och korruption. Korruption är dock ett vitt begrepp som härstammar från det latinska ordet corrumpere, vilket betyder muta. Följaktligen omfattas den straffrättsliga terminologin av givande och tagande av muta av begreppet korruption. Korruption anses vara ett medel för att otillbörligen påverka besluts- och handlingsprocesseSweden has long been considered a country free from nepotism and corruption. Corruption is however a broad term which derives from the Latin word corrumpere, meaning bribe. Consequently the criminal terminology of giving and receiving bribes comprises the concept of corruption. Corruption is a way to improperly influence the decision making and processes in a society. The damaging effects on a soc
During the last few years, crowding effects on the physics of proteins has become an increasingly popular topic of research. This is is because most biological processes involving proteins naturally take place in a crowded environment, e.g. in the cellular environment where macromolecules may occupy 30% of the volume. One such biological process would be the formation of amyloid aggregates, which
Many houses of the “miljonprogrammet” is now facing a major improvement need, and not least in terms of energy improvement, Drottninghög in Helsingborg is one such area. It is a houses from Drottninghög that is used as an example in this report. The energy improvements addressed in this report is mainly concerning construction improvements. The building from Drottninghög is poorly insulated whit t
Aim: We aimed to study the feasibility and tolerability of a combination therapy consisting of glutamic acid decarboxylase (GAD-alum), Etanercept and vitamin D in children and adolescents with newly diagnosed with type 1 diabetes (T1D), and evaluate preservation of beta cell function. Material and Methods: Etanercept Diamyd Combination Regimen is an open-labelled multi-centre study pilot trial whi
Background and aims: Histopathology is the gold standard for analysis of atherosclerotic plaques but has drawbacks due to the destructive nature of the method. Ex vivo MRI is a non-destructive method to image whole plaques. Our aim was to use quantitative high field ex vivo MRI to classify plaque components, with histology as gold standard.Methods: Surgically resected carotid plaques from 12 patie
Background: Research has indicated that interactive, computerized case simulations using immersive virtual reality (VR) technology may be beneficial in the augmentation of conventional methods of assessment and treatment in forensic psychiatry, primarily through providing an engaging and safe environment in which the user can practice and learn skills and behaviors. However, there does not appear
Emissions from aviation are expected to grow. With evidence that the International Civil Aviation Organization’s Carbon Offsetting and Reduction Scheme for International Aviation is an inadequate mitigation mechanism, there is interest in upscaling the sector’s climate-related policies. This paper reviews potential aviation emissions mitigation policies against the background of emerging complexit
