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Phosphorylation of extracellular-signal-regulated kinase 1/2 (p-ERK 1/2) was investigated by immunohistochemistry at 30 min, 1 h, and 48 h after nerve transection in the sciatic nerve of healthy and diabetic [streptozotocin (STZ)-induced diabetes mellitus and BioBreeding (BB; i.e. DR.lyp/lyp or BBDP)] rats. Transection injury increased the intensity of p-ERK 1/2 in nerve stumps at all time points.

Popular Abstract in Swedish See attachment in related materialThe combustion engine is today the dominant technology for transportation of goods and people world-wide. Concerns for global warming, toxic exhaust emissions, as well as cost and availability of fuel have in recent years created incentives for technological evolution of combustion engines. More sophisticated engine instrumentation with additional degrees of freedom has been added to the engine de

The Mendelian Society in Lund was founded in 1910. The initiative came from two young biologists supported by a wide circle of interested plant breeders and academics. Already from the start the society was dominated by the towering personality Herman Nilsson-Ehle. After two active years, the Society went into temporal hibernation until it resumed its activities in spring 1916, when Nilsson-Ehle w

This doctoral dissertation presents the development and digital hardware realization of cardiac event detectors. Implantable medical appliances, as the cardiac pacemaker, have progressed from a life sustaining device to a device that considerably improves life quality for all ages. The number of electronic devices and household appliances in everyday live has an ongoing exponential growth. The

Background Several new therapeutic options for psoriasis have been tested in clinical trials in recent years. Choice of comparator, study duration and outcome measures are critical for interpreting application of trial results to clinical practice. Objectives We examined whether these trial aspects have changed substantially in recent years in comparison with the past. Methods A systematic search

The chemical composition and dissociation behaviour of water adsorbed on clean and oxygen pre-covered Pd{111} was studied using high-resolution time-resolved and temperature-programmed X-ray photoelectron spectroscopy. We find that water remains intact at all temperatures up to desorption on the clean surface and at high oxygen coverage(0.69 ML) when a surface oxide is formed. The highest desorpti

The standard model (SM) of particle physics is spectacularly successful, yet the measured value of the muon anomalous magnetic moment (g - 2)mu deviates from SM calculations by 3.6 sigma. Several theoretical models attribute this to the existence of a "dark photon," an additional U(1) gauge boson, which is weakly coupled to ordinary photons. The PHENIX experiment at the Relativistic Heavy Ion Coll

Popular Abstract in Swedish Introduktion: Validitet handlar enkelt uttryckt om överensstämmelse med sanningen eller exempelvis om ett instrument mäter det som är avsett. Validitet kan också ses som ett mer komplext begrepp, innefattande aspekter som nytta, relevans, värderingar och sociala konsekvenser. Validitet förutsätter reliabilitet som är ett mått på tillförlitlighet, noggrannhet eller reproAbstract Introduction: Validity is important at different levels in psychiatry. Valid structured instruments are important aids in screening and diagnostics, in both research and clinical practice. An aim of the diagnostic procedure is to yield valid diagnoses. Ultimately, the validity of structured instruments (non-empirical) and clinical diagnoses depends on the validity of the diagnostic class

G.fast is a new standard from the International Telecommunication Union, which targets 1 Gb/s over short copper loops using frequencies up to 212 MHz. This new technology requires accurate parametric cable models for simulation, design, and performance evaluation tests. Some existing copper cable models were designed for the very high speed digital subscriber line spectra, i.e., frequencies up to

Access to court is essential for the protection of all rights of individuals. The same holds true for the rights individuals derive from Community law. The Court of Justice of the European Communities (ECJ) is the only court competent to review the legality of acts of the Community institutions. In addition, the ECJ has the last word on the interpretation of Community law. Yet, direct access for i

BACKGROUND: Tuberculosis remains a leading infectious cause of death in resource-limited settings. Effective treatment is the cornerstone of tuberculosis control, reducing mortality, recurrence and transmission. Supporting treatment adherence through facility-based observations of medication taking can be costly to providers and patients. Digital adherence technologies (DATs) may facilitate treatm

Background: The burden of Parkinson’s disease (PD) worsens with disease progression. However, the lack of objective and uniform disease classification challenges our understanding of the incremental burden in patients with advanced Parkinson’s disease (APD) and suboptimal medication control. The 5–2-1 criteria was proposed by clinical consensus to identify patients with advancing PD. Our objective

A phenomenological model for simulating photoplethys-mogram (PPG) during paroxysmal atrial fibrillation (AF) is proposed. A PPG pulse is modeled by combining a lognormal and two Gaussian waveforms. Continuous PPG signals are produced by placing and connecting individual pulses according to the RR interval pattern extracted from annotated ECG signals. This paper presents a practical application of

The main goal with this thesis is to develop a method to maximize the fuel efficiency [ton/l] in construction machines, while fulfilling the desired productivity [ton/h]. This is achieved by focusing on two of the main influencers; the machine concept evaluation and the development of operator assist systems. To be able to perform a concept evaluation that is unbiased from control engineering expe

Rotary vacuum filters (RVFs) with adiatomaceous earth (kieselguhr) coatings as filter aid are the most established technology for the removal of the so-called mud fraction after liquefaction and saccharification in the production of starch-based sweeteners. The RVFs is an open process which is further associated with the use of filters resulting in an increasing disposal challenge. Based on this t

The extraction of spectral information in the inversion process of time-domain (TD) induced polarization (IP) data is changing the use of the TDIP method. Data interpretation is evolving from a qualitative description of the subsurface, able only to discriminate the presence of contrasts in chargeability parameters, towards a quantitative analysis of the investigated media, which allows for detail

Abstract: Bladder cancer is a heterogenous disease, ranging from minimally invasive, low-grade tumours with lowrecurrence rates and mortality on one end of the spectrum, and muscle invasive, high-grade disease prone torecurrence, progression and death at the other end.The aim of this thesis was to investigate the expression, clinicopathological correlates and prognostic significanceof the candidat