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Dealing with the heterogeneity of breast tumors and treating breast cancer patients pose a great challenge. The heterogeneity within and between tumors indicates that each case of breast cancer may have a good prognosis and could benefit from tailored therapies. Breast cancer is a condition that undergoes changes as the tumor progresses and metastasizes, which presents further challenges for imple
Postal address Box 7080 Visiting address Tycho Brahes väg 1 Telephone +46 46 222 00 00 E-mail fredrik.andersson@ehl.lu.se Website www.lusem.lu.se Department o f Economics General Syllabus for Third-Cycle Studies in Economics for the Degree of Doctor at Lund University School of Economics and Management The syllabus for third-cycle studies in Economics was adopted by the Board of the School of Econ
https://www.lusem.lu.se/sites/lusem.lu.se/files/2024-01/FU-asp-nek-en.pdf - 2026-07-17
We report the vortex dynamics of tellurium substituted FeSe1-xTex superconducting thin films. The electric field versus current density (E-J) curve for films with low Te substitution is still governed by the thermally activated flux flow model at temperatures as low as 0.5T(C)(offset). In contrast, we clearly observed a vortex liquid-glass transition in films with high Te substitution. The E-J cur
We review the basic principles of ultrafast charge delocalization phenomena in aqueous electrolytes following core-level photoionization and resonant core-level excitations, and describe how these processes can be probed using Auger electron spectroscopy. The use of the core-hole clock method to extract dynamical information from Auger spectra is described. By a number of examples we demonstrate h
Ferrochelatase catalyzes the metallation of protoporphyrin IX in the terminal step of heme biosynthesis. Mutations in the ferrochelatase gene can lead to the disease erythropoietic porphyria. The catalyzing mechanism of ferrochelatase is still not fully understood. In this paper, we have studied the insertion of Fe2+ into the protoporphyrin IX ring by Bacillus subtilis ferrochelatase using combine
Biochemical reactions powered by ATP hydrolysis are fundamental for the movement of molecules and cellular structures. One such reaction is the encapsidation of the double-stranded DNA (dsDNA) genome of an icosahedrally symmetric virus into a preformed procapsid with the help of a genome-translocating NTPase. Such NTPases have been characterized in detail from both RNA and tailed DNA viruses. We p
The catalytic properties of cellobiose dehydrogenase (CDH) from the ascomycete fungus Myriococcum thermophilum adsorbed on a graphite electrode were investigated for a large variety of carbohydrate substrates. The effects of applied potential, pH and buffer composition were tested and optimized, and the most suitable conditions were used to evaluate the detection limit, linear range, and sensitivi
OBJECTIVE: The aim of this study was to determine whether bone quality, as assessed by osteometry and histologic parameters, can be used to predict implant integration in conjunction with maxillary sinus reconstruction. STUDY DESIGN: Twelve patients with severely atrophied maxillary alveolar processes were treated through use of a two-stage surgical reconstructive strategy with implant placement 4
Matrilin-2 is a component of extracellular filamentous networks. To study the interactions by which it can be integrated into such assemblies, full-length and truncated forms of matrilin-2 were recombinantly expressed in HEK-293 cells and purified from conditioned medium. The recombinant proteins, when used in interaction assays, showed affinity to matrilin-2 itself, but also to other collagenous
The title compound, lithium potassium dialuminium diger-manium octaoxide dihydrate, (K,Li)-(Al,Ge)-GIS (GIS is gismondine), is the result of a 50% Li+ exchange into the K-(Al,Ge)- GIS structure. The (K,Li)-(Al,Ge)-GIS structure was determined from a 4 x 4 x 2 m m octahedral single crystal at the ESRF synchrotron X-ray source. The ion exchange results in a symmetry transformation from I2/a for K-(A
We present the resonant inelastic X-ray scattering (RIXS) spectra of BeO at the Be 1s photoabsorption edge. The RIXS spectra excited in the vicinity of the core exciton resonance show two principal features: the scattering on a valence exciton (which at higher excitation energies verges into the characteristic K alpha emission), and a remarkably strong energy loss side-band to the elastic scatteri
The conventional inversion of surface waves depends on modal identification of measured dispersion curves, which can be ambiguous. It is possible to avoid mode-number identification and extraction by inverting the complete phase-velocity spectrum obtained from a multichannel record. We use the fast simulated annealing (FSA) global search algorithm to minimize the difference between the measured ph
Ungdomsreduktionen i 29 kap. 7 § brottsbalken som innebär straffnedsättning för unga lagöverträdare vid straffmätning har under de senaste åren varit under omfattande förändring i straffskärpande riktning. Utvecklingen bryter mot en tradition av mildare straff för unga. Unga har länge särbehandlats straffrättsligt men detta har i större omfattning börjat ifrågasättas, då särbehandlingen kan anses The reduced sentence for juveniles in Chapter 29, Section 7 of the Swedish Penal Code, which entails a reduced sentence for young offenders at the meting out of punishment has in recent years undergone significant changes in a more severe direction. The development marks a departure with a tradition of more lenient punishment for young offenders. Juveniles have long been treated differently in cri
Abstract in UndeterminedThe rarefaction technique is applied to two Holocene pollen sequences (covering the last 12,000 calendar years) from two lakes in southern Sweden. One represents an open agricultural landscape, the other a partly wooded and less cultivated landscape. The inferred palynological richness is interpreted as an approximate measure of floristic diversity at the landscape scale. T
The Swedish Family-Cancer Database was expanded to include all Swedes born in 1932 and later (offspring) with their parents, totaling 10.2 million individuals. Cancer cases were retrieved from the Swedish Cancer Registry from the years 1958 to 1998, including over 1 million primary cancers and in situ tumors. Some 10%, of offspring diagnosed with cancer lack any parental information. Incidence rat
There have been recently multiple calls to investigate the rhythmic behaviors (RBs) of nonhuman animals, as a way to gain insight into the evolution of human rhythm cognition and musicality. Currently, the empirical data from non-human species is scarce. Most strikingly, we lack data from chimpanzees (Pan troglodytes), our closest genetic relatives. Here, we present an observational study conducte
Tetracycline resistance protein Tet(O), which protects the bacterial ribosome from binding the antibiotic tetracycline, is a translational GTPase with significant similarity in both sequence and structure to the elongation factor EF-G. Here, we present an atomic model of the Tet(O)-bound 70S ribosome based on our cryo-electron microscopic reconstruction at 9.6-Å resolution. This atomic model allow
We report on the cytogenetic studies, performed in a routine cytogenetic laboratory between 1981 and 1986, on 428 subjects: 291 probands with non‐specific mental retardation, 101 first‐degree relatives of fra(X) positive patients and 36 non‐retarded patients, referred for other reasons. As a rule 50 cells, cultured in folate‐deficient medium were analysed. The results are compared with data collec
