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Dose-effect relationship of apoptosis induced by fission-neutron in murine thymocytes

Objective To investigate the effectiveness of high LET fission-neutron to induce apoptosis in murine thymocytes and to compare it with that of low LET 60Co γ-ray. Methods Apoptosis induction was studied qualitatively by light and transmission electron microscopy and DNA gel electrophoresis,also quantitatively by flow cytometry(FCM) and diphenylamine (DPA)methods. Results DNA ladders of murine thym

Development and Validation of a Risk Score Predicting Substantial Weight Gain over 5 Years in Middle-Aged European Men and Women

Background: Identifying individuals at high risk of excess weight gain may help targeting prevention efforts at those at risk of various metabolic diseases associated with weight gain. Our aim was to develop a risk score to identify these individuals and validate it in an external population. Methods: We used lifestyle and nutritional data from 53 degrees 758 individuals followed for a median of 5

The variability of processes involved in transgene dispersal-case studies from Brassica and related genera

Background, aim, and scope We strive to predict consequences of genetically modified plants (GMPs) being cultivated openly in the environment, as human and animal health, biodiversity, agricultural practise and farmers' economy could be affected. Therefore, it is unfortunate that the risk assessment of GMPs is burdened by uncertainty. One of the reasons for the uncertainty is that the GMPs are int

Seedling Stage Strategies as a Means of Habitat Specialization in Herbaceous Plants

The regeneration niche has been little investigated in studies of community assembly and plant distribution. We examined adaptive associations between seedling traits and habitat specialization. Two habitat contrasts were investigated across several evolutionary lineages of angiosperms: species specialized to forest vs. open habitats and to dry vs. wet habitats. We also tested whether effects of s

Silicone Membrane Equilibrator: Measuring Chemical Activity of Nonpolar Chemicals with Poly(dimethylsiloxane) Microtubes Immersed Directly in Tissue and Lipids.

The chemical activity of organic chemicals directs their diffusion and partitioning and is consequently crucial for their transport, distribution, and toxic effects. A silicone membrane equilibrator is introduced for measuring the chemical activity of nonpolar organic chemicals in lipid-rich samples: (I) A 6 m poly(dimethylsiloxane) (PDMS) microtube (300 mum i.d., 640 mum o.d.) was placed in a sam

Shifts in plant respiration and carbon use efficiency at a large-scale drought experiment in the eastern Amazon

P>The effects of drought on the Amazon rainforest are potentially large but remain poorly understood. Here, carbon (C) cycling after 5 yr of a large-scale through-fall exclusion (TFE) experiment excluding about 50% of incident rainfall from an eastern Amazon rainforest was compared with a nearby control plot. Principal C stocks and fluxes were intensively measured in 2005. Additional minor compone

Binding of complement regulators to invasive nontypeable Haemophilus influenzae is not increased compared to nasopharyngeal isolates, but serum resistance is linked to disease severity.

The aim of the present study was to analyse the importance for non-typeable Haemophilus influenzae (NTHi) isolated from patients with sepsis (invasive isolates) compared to nasopharyngeal isolates from patients with upper respiratory tract infection to resist the complement-mediated attack in human serum and to correlate this to disease severity. We in detail studied and characterized cases of inv

Design of a horizontal neutron reflectometer for the European Spallation Source

A design study of a horizontal neutron reflectometer adapted to the general baseline of the long pulse European Spallation Source (ESS) is presented. The instrument layout comprises advanced solutions for the neutron guide, high-resolution pulse shaping and beam bending onto a sample surface being thoroughly adjusted to the properties of the ESS. The length of this instrument is roughly 55 m, enab

The palaeolimnological record of regime shifts in lakes in response to climate change

Popular Abstract in Swedish Traditionellt sett har man tänkt sig att gradvisa förändringar i yttre miljöfaktorer leder till lika gradvisa ekosystemförändringar, men vi vet nu att ekosystem som utsätts för mänsklig påverkan eller klimatförändringar kan reagera kraftigt och abrupt genom att ett ekologiskt tröskelvärde överskrids varvid en förändring sker från en stabil ekologisk situation till en anRegime shifts in lake ecosystems can occur in response to both abrupt and continuous climate change, and the imprints they leave in palaeolimnological records allow us to investigate and better understand patterns and processes governing ecological changes on geological time scales. This thesis aims at investigating palaeolimnological records of regime shifts in lakes during the Holocene to explor

Barriers and distances as determinants for the evolution of bird migration links: the arctic shorebird system

We analysed migratory connectivity between different winter quarters and breeding sectors in the circumpolar tundra region for arctic shorebirds, in relation to migratory distances and ecological barriers. Total distances and barriers were calculated and measured for all potential migratory orthodrome links between 10 selected winter regions and 12 breeding sectors. The migratory segment between t

Intrapleural fluid movements described by a porous flow model

We injected technetium-labeled albumin (at a concentration similar to that of the pleural fluid) in the costal region of anesthetized dogs (n = 13) either breathing spontaneously or apneic. The decay rate of labeled activity at the injection site was studied with a gamma camera placed either in the anteroposterior (AP) or laterolateral (LL) projection. In breathing animals (respiratory frequency a

Phosphatidylethanol as a sensitive and specific biomarker-comparison with gamma-glutamyl transpeptidase, mean corpuscular volume and carbohydrate-deficient transferrin

Phosphatidylethanol (PEth), a direct ethanol metabolite, is detectable in blood for more than 2 weeks after sustained ethanol intake. Our aim was to assess the usefulness of PEth [comparing sensitivity, specificity and the area under the curve (AUC)] as compared with carbohydrate-deficient transferrin (CDT), gamma-glutamyl transpeptidase (GGT) and mean corpuscular volume (MCV), calculating the res

Asbestos and cancer: An overview of current trends in Europe

This review assesses the contribution of occupational asbestos exposure to the occurrence of mesothelioma and lung cancer in Europe. Available information on national asbestos consumption, proportions of the population exposed, and exposure levels is summarized. Population-based studies from various European regions on occupational asbestos exposure, mesothelioma, and lung cancer are reviewed. Asb

Recruitment from resting stages among bloom-forming cyanobacteria

Popular Abstract in Swedish BLÅGRÖNALGERS VILOSTADIER—EN VIKTIG LÄNK TILL ALGBLOMNINGAR ALGBLOMNINGAR Algblomningar i Östersjön och i många av våra sydsvenska insjöar har blivit ett vanligt inslag sommartid. Vi vet att övergödning av våra vatten orsakar detta genom att överskottsnäring tillför's från olika mänskliga aktiviteter från land. Dock vet vi inte exakt vad det är som styr när och hur desCyanobacteria are known to form heavy blooms in eutrophicated freshwaters and also form resting stages, associated with the sediments, during harsh growth conditions. These resting stages can serve as inoculum for pelagic populations and function as a potential source for bloom formations. However, the factors involved in initiating recruitment from resting stage to the pelagic phase are not fully

Membrane Filtration for Fractionation of Biomass Compounds - Process Design for the Separation of Hemicelluloses and Lignin from Alkaline Solutions

Popular Abstract in Swedish Ny innovativ processdesign har resulterat i två processer som kan göra tillverkningen av förnyelsebara plaster och bränslen konkurrenskraftiga mot dagens fossila alternativ. Den nya designen har gjort vissa processteg upp mot 40 gånger så effektiva som med dagens teknik. Vikten av att ställa om dagens samhälle, som till stor del är beroende av fossila resurser, till eIt is important to replace fossil resources such as oil, coal and natural gas with renewable raw materials for the production of materials and fuels in order to reduce environmental impact. Furthermore, these raw materials should preferably be residues, e.g. agricultural or forest residues, in order not to compete with the production of human food and animal feed. High molecular weight arabinoxyla