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Popular Abstract in Swedish Det kvinnliga könshormonet östrogen utövar sin effekt via två bindningsprotein (receptorer) benämnda ERa och ERb. Då östrogen binder till receptorn aktiverar alternativt inaktiverar detta komplex sekvenser av DNA molekylen. Således reglerar den aktiverade receptorn för östrogen genaktivitet och därmed syntes av proteiner viktiga för den normala cell- och vävnadsfunktionEstrogen receptors (ER) are expressed not only in classical target organs for estrogen like breast and uterus, but also in male reproductive system as well as in non-reproductive organs such as brain, liver and bone. The functions of ER are quite well known in reproductive organs but less information is available regarding their function in vascular tissue. The objective of this thesis was to inve

BACKGROUND:: Early-term birth (gestational age, 37-38 weeks) has been associated with increased infant mortality relative to later-term birth, but mortality beyond infancy has not been studied. We examined the association between early-term birth and mortality through young adulthood. METHODS:: We conducted a national cohort study of 679,981 singleton births in Sweden in 1973-1979, followed up for

BACKGROUND: Most cardioplegic solutions have been developed using the classic Langendorf heart perfusion model, which only allows a short experimental follow-up. Our aim was to investigate hearts after prolonged storage by using a physiologic model including prolonged perfusion with normal, fresh blood. METHODS: Sixteen hearts from 60-kg pigs were preserved with dextran-enriched (dextran-40, 35 g/

BACKGROUND: Cerebral ischemia from middle cerebral artery wall (MCA) occlusion results in increased expression of cerebrovascular endothelin and angiotensin receptors and activation of the mitogen-activated protein kinase (MAPK) pathway, as well as reduced local cerebral blood flow and increased levels of pro-inflammatory mediators in the infarct region. In this study, we hypothesised that inhibit

Object. The authors investigated whether cyclosporin A (CsA), a cyclophilin ligand with mitochondrial permeability transition pore-blocking and calcineurin-inhibiting properties, affects motor function, neuronal death, and life span in the G93A transgenic mouse model of familial amyotrophic lateral sclerosis (FALS). Methods. The G93A mice received weekly intracerebroventricular injections of CsA (

Popular Abstract in Swedish I tider av samhällsförändringar uppträder nya organisationer. De är beroende av att mobilisera resurser från en omgivning som präglas av en gammal ordning. De måste då anpassa sig för att överleva. I denna process är härmandet en central mekanism. Nya organisationer lär sig att överleva genom att härma sin omgivning. Detta leder i sin tur till att de tenderar att bli alNew organizations emerge in times of social change. Their survival depends on their ability to mobilize resources in an environment defined by an old order, and thus they must adapt to it. Since new organizations learn how to adapt by mimicking already succesful organizations, their structure tend to become increasingly similar to the structure of those organizations. The thesis tells the story of

UPPLEVELSER AV SVENSK FILM offers a broad understanding of Swedish cinema during the years between 1985 and 2000. The dissertation focuses on those Swedish films that have been given a wide distribution, i.e. films that in many cases can be considered popular films. (Films that have only obtained a marginal position in the cinemas have not been included.) The films studied attract an average of 2,

I takt med att världen globaliseras allt mer uppstår också nya typer av utma-ningar. Skatteplanering och skatteflykt orsakar idag stor skada på länders skattebas. För att motverka detta har OECD sedan 2013 arbetat med ett pro-jekt som kallas för BEPS (Base Erosion and Profit Shifting). BEPS består av 15 åtgärder för att motverka erodering av skattebasen och vinstallokering. Projektet har beskrivitAs the world becomes increasingly globalized, new types of challenges arise. Tax planning and tax evasion continue to cause significant harm to the tax bases of countries. To combat this, the OECD has been working on a project called BEPS (Base Erosion and Profit Shifting) since 2013. BEPS consists of 15 actions aimed at countering the erosion of the tax base and profit shifting. The project has b

Smartphones are an increasingly important part of our lives. As services that treat sensitive information are found on most modern phones, there is a growing need for security. The common approaches of entering a PIN-code or some pattern when accessing an application on the phone is not necessarily sufficient, as they are vulnerable to different types of attacks. The embedded sensors of modern sma

The development of electrical circuit boards is increasing and the time spent in the development stage can be quite long. The thesis has tried to shorten the time spent developing new electrical circuit boards, by first finding a common denominator for efficiency losses in the development process and then implementing an example solution. The problem identified was the lack of attention towards pr

Denna uppsats syftar till att undersöka och redogöra för uppkomsten av fängelsestraffet som självständig straffsanktion i Sverige samt analysera den straffrättsteoretiska diskurs som därmed följde. Genom tillämpande av en rättsdogmatisk metod har uppsatsens frågeställningar besvarats – när uppkom fängelsestraffet som självständig straffsanktion och varför uppkom det när det uppkom, samt vad handlaThe purpose of this thesis is to examine and describe the origins of the sentence imprisonment as an independent punishment in Sweden, and to analyze the discourse concerning theory of punishment that followed. Through applying a legal dogmatic method the questions of the thesis are answered – when did imprisonment arise as an independent punishment and why then, what was the discourse concerning

Ecosystem modelling is an always evolving science trying to catch the complexity of the nature and its principles to model environmental responses in a realistic way. Over and over, models try to introduce more variables and interactions to achieve better representations of phenomena of interest like the responses of the ecosystem to a fast changing world (climate change, land use change). LPJ-GUE

At Haväng in eastern Scania, South Sweden, an underwater landscape occurs on the seabed. The landscape consists of deep-rooted pines standing in organic deposits. Due to sea level changes, the area was exposed during two phases (11,700 to 10,700 and 10,000 to 8,500 years ago) so that pines could live there, to subsequently drown and end up submerged. This study aims to show how the Baltic Sea form

Over the last few years there has been a steady increase in interest in the exploration of perovskite materials within photovoltaic research. This can to a large extent be attributed to the incredible pace at which solar cells based on perovskites have improved in efficiency during the same time period. Perovskite solar cells (SCs) are not only an alternative to today’s market leading silicon base

I Alternativa övningsmetoder för musiker – del 1 presenteras olika sätt på vilka musikaliska färdigheter kan övas genom mentalisering och andra alternativa övningsmetoder som inte inkluderar användande av musikernas huvudinstrument. Den visar också hur dessa metoder kan kombineras. Här beskrivs även hur och varför dessa arbetssätt fungerar för musikalisk instudering individuellt och i en duo samt Alternative Methods of Practising Music – A study of practising without one’s main instrument for single musicians and small ensembles – Part 1 presents different ways in which musical skills can be practised through imagery and other alternative methods of practising that do not involve the use of the musicians’ main instruments. It also shows how these methods may be combined. Furthermore, it de

Att jordbruksmark bebyggs har under senare tid blivit en alltmer aktuell fråga och har skapat debatt kring skyddet av jordbruksmark. Lagstiftningen om detta skydd återfinns i 3 kap. 4 § miljöbalken (1998:808) där det anges att jordbruk är av nationell betydelse. Vidare gäller enligt paragrafen att brukningsvärd jordbruksmark får bebyggas för väsentliga samhällsintressen endast om inte annan mark, The fact that agricultural land is being exploited has become a more present question and has created a debate regarding the protection of agricultural land. The legislation of this protection is found in Chapter 3 Section 4 of the Swedish Environmental Code (1998:808) which states that agriculture is a national interest. Furthermore, it states that land suitable for cultivation may be exploited f

Language and gesture are two semiotic systems that work together in close integration during communication. One issue in particular, that of image schemas, has been studied in relation to gestures, though most often in adult gesture and communication (Williams, forthcoming; Cienki, 2013; Mittelberg, 2006, 2018). This contrasts with mimetic schemas, which are thought to be more specific structures

Fermentation is a process that utilizes live microorganisms to produce different biological products such as enzymes. The oxygen mass transfer rate is often the limiting factor in aerobic fermentations and thereby an important process parameter. The initial aim of this MSc thesis was therefore to develop a soft sensor for the volumetric oxygen mass transfer coefficient, kLa, in order to monitor it

Research question: How do social relationships and social interactions shape the behavior of young consumers on Social Media and Communication Apps? Purpose: The purpose of this study is to enhance the understanding of how the Social Customer Journey influences the purchasing behavior of young consumers on Social Media and Communication Apps. Furthermore, the study aims to explore the dynamics o