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Populärvetenskaplig sammanfattning: En verksamhet eller åtgärd kan ha stor inverkan på människor, djur, växter, mark, vatten, luft, klimat, landskap och kulturmiljö. För att fatta bästa möjliga beslut om en projekt-ut-formning som tar hänsyn till konsekvenserna för olika berörda miljövärden åter-finns kravet på miljökonsekvensbeskrivning, MKB, i svensk lagstiftning. Syftet med en MKB är att identiAn activity or a measure might have a great impact on people, animals, plants, soil, water, air, climate and landscape. In order to describe the direct and indirect effects an intended activity might have an Environmental Impact Assessment (EIA) must be carried out. This demand is regulated in Swedish legislation and makes it possible to achieve as small impact on the environment as practicable. A

Isolation and characterization of neural precursor cells from the Sox1–GFP reporter mouse Isolation and characterization of neural precursor cells from the Sox1–GFP reporter mouse Perrine Barraud,* Lachlan Thompson,* Deniz Kirik, Anders Björklund and Malin Parmar Wallenberg Neuroscience Center, BMC A11, Section of Neurobiology, and Lund Strategic Research Center for Stem Cell Biology and Cell The

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/barraud_et_al_eur_j_neurosci_2005.pdf - 2026-07-22

Inappropriate surface expression of voltage-gated Ca(2+)channels (CaV) in pancreatic ß-cells may contribute to the development of type 2 diabetes. First, failure to increase intracellular Ca(2+) concentrations at the sites of exocytosis impedes insulin release. Furthermore, excessive Ca(2+) influx may trigger cytotoxic effects. The regulation of surface expression of CaV channels in the pancreatic

In the first of two essays in this Journal, I seek to unify the historical geography of early modern 'European expansion' (Iberia and Latin America) with the environmental history of the 'transition to capitalism' (northwestern Europe). The expansion of Europe's overseas empires and the transitions to capitalism within Europe were differentiated moments within the geographical expansion of commodi

In the human gut, millions of bacteria contribute to the microbiota, whose composition is specific for every individual. Although we are just at the very beginning of understanding the microbiota concept, we already know that the composition of the microbiota has a profound impact on human health. A key factor in determining gut microbiota composition is diet. Preliminary evidence suggests that di

Written daily reflections during clinical practice on birthing units have been used during several years in midwifery education at Lund University, Sweden. However, the usefulness of these reflections for evaluation of progression in learning and professional development of students has to date not been evaluated. In order to analyse written reflections, two taxonomies developed by Bloom and Pette

Context Small single-center studies have shown that cerebrospinal fluid (CSF) biomarkers may be useful to identify incipient Alzheimer disease (AD) in patients with mild cognitive impairment (MCI), but large-scale multicenter studies have not been conducted. Objective To determine the diagnostic accuracy of CSF beta-amyloid(1-42) (A beta 42), total tau protein (T-tau), and tau phosphorylated at po

The work of mitochondria and chloroplasts is energy transduction in respiration and photosynthesis. The physico-chemical mechanisms of bioenergetics do not directly involve genes and heredity, and furthermore, redox chemistry is intrinsically mutagenic. Thus the small, functional genomes of mitochondria and chloroplasts are an oddity. Although extensively sequenced and catalogued, cytoplasmic geno

The present study was designed to analyse whether continuous overexpression of glial cell line-derived neurotrophic factor (GDNF) in the striatum by a recombinant lentiviral vector can provide improved cell survival and additional long-term functional benefits after transplantation of fetal ventral mesencephalic cells in Parkinsonian rats. A four-site intrastriatal 6-hydroxydopamine lesion resulte

Questions: (1) Does soil acidification in calcareous sandy grasslands lead to loss of plant diversity? (2) What is the relationship between the soil content of lime and the plant availability of mineral nitrogen (N) and phosphorus (P) in sandy grasslands? Location: Sandy glaciofluvial deposits in south-eastern Sweden covered by xeric sand calcareous grasslands (EU habitat directive 6120). Methods:

A method for simultaneous extraction and quantification Of four non-steroidal anti-inflammatory drugs (NSAIDs) based on continuous flow hollow fiber liquid-phase microextraction (CFHF-LPME) was developed. The effect of sample flow rate, acceptor flow rate, type of acceptor flow (continuous, semi-continuous or forward-backward), type of supported liquid membrane and sample volume was studied. The e

Background: Local pain at the site of intravenous (iv) injection of propofol remains a considerable problem in clinical anaesthesiology, and particularly so in infants. The aim of the present study was to compare the influence of two different emulsions of propofol on local pain following iv administration. Methods: Eighty adult patients (ASA I-II) scheduled for ear-nose-throat or plastic surgery

Rationale Vitamin D has been shown to be involved in the host immune response toward Mycobacterium tuberculosis. Objectives: To test whether vitamin D supplementation of patients with tuberculosis (TB) improved clinical outcome and reduced mortality. Methods: We conducted a randomized, double-blind, place-bocontrolled trial in TB clinics at a demographic surveillance site in Guinea-Bissau. We incl

Changes in technologies which have put computing power on the desktop over the past 25 years give an impression of increased empowerment for the end-user when compared to previous generations of hardware and software. However, in practice, latest developments in desktop computing and related technologies have led to more and more centralized control of ‘end-users’ workspaces. This phenomenon leads

It is shown that the isoscalar strength in the energy region just above the low energy threshold, which is created by exciting particles to the continuum in nuclei far from β-stability lines, can be reduced by the attractive coupling to isoscalar shape oscillations. This is in contrast to the well known fact that in β-stable nuclei low lying isoscalar particle hole strengths are always increased b

Popular Abstract in Swedish I den här avhandlingen studeras de elektriska egenskaperna hos nanotrådar av halvledarmaterial. En halvledare är ett mellanting av en ledare och en isolator, där den elektriska ledningsförmågan kan styras både genom att förorena materialet med andra ämnen och genom att påverka materialet med ett elektriskt fält. I princip all modern elektronik bygger på komponenter av hThis thesis focuses on electron transport in semiconductor InAs/InP and InSb nanowire quantum devices. However, first the temperature dependence of classical charge transport in InSb nanowire field-effect transistors, FETs, is characterized, using InAs nanowire FETs as a reference. We find that the InSb FETs, in the same way as InAs FETs, are n-type with good current saturation and low voltage ope

Summary form only given. In this paper, we examine the effect of block size on the performance of trellis based quantization. In particular, the Viterbi and tailbiting BCJR algorithms are compared. It is shown that for short blocks of data, the T-BCJR algorithm achieves a superior performance over the Viterbi algorithm (VA). One approach is to use the maximum a posteriori probability (MAP) heurist

TGFα is a member of the epidermal growth factor (EGF) family and is one of the ligands for the EGF- receptor. The precursor of TGFα, pro-TGFα, is a transmembrane protein. The aim of this project has been to establish a model for studies of pro-TGFα effects on EGF receptor signalling, in particular through Gab1, a docking protein involved in PI3K/Akt signalling pathway. The experiments in this thes