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A Monosaccharide Residue Is Sufficient to Maintain Mouse and Human IgG Subclass Activity and Directs IgG Effector Functions to Cellular Fc Receptors.

Immunoglobulin G (IgG) glycosylation modulates antibody activity and represents a major source of heterogeneity within antibody preparations. Depending on their glycosylation pattern, individual IgG glycovariants present in recombinant antibody preparations may trigger effects ranging from enhanced pro-inflammatory activity to increased anti-inflammatory activity. In contrast, reduction of IgG gly

Early TCR alpha beta expression promotes maturation of T cells expressing Fc epsilon RI gamma containing TCR/CD3 complexes

In a previous study we presented data indicating that the expanded population of CD4(-)CD8(-) (DN) alphabeta T cells in TCRalpha-chain-transgenic mice was partially if not entirely derived from gammadelta T cell lineage cells. The development of both gammadelta T cells and DN alphabeta T cells is poorly understood; therefore, we thought it would be important to identify the immediate precursors of

Recombinant factor IX Fc for the treatment of hemophilia B

Current hemophilia B treatment guidelines recommend routine prophylaxis with factor IX (FIX) replacement products, tailored to maintain plasma activity at levels that will prevent bleeds. However, plasma FIX activity may not be the primary determinant or best indicator of hemostatic efficacy due to its extravascular distribution. FIX replacement therapy has evolved to include extended half-life (E

Status Spotting- A Consumer Cultural Exploration into Ordinary Status Consumption of "Home" and Home Aesthetics

Popular Abstract in Swedish När man förenar idéerna “status” och “konsumtion” tänker många automatiskt på dyra varumärken, konspikuös lyx, bling-bling och spektakulär extravaganza. Inte minst i fallet “hem” går associationerna till Hollywood-stjärnor, enorma villor, kända arkitekter, swimming pools och dyr möbeldesign-hysteri. Men, givet att de flesta människor inte har medlen, och kanske mer viktWhen lumping the notions of “status” and “consumption” together, people often think of expensive brands, conspicuous luxury, bling-bling and spectacular extravaganza. Not least in the case of the “home,” such associations go to Hollywood stars, spacious mansions, famous architects, swimming pools, and high-priced furniture design frenzy. But given that most people don’t have the means, and perhaps

Humanitära Interventionens internationella definition - En analys av det kontroversiella undantaget från FN-stadgans allmänna våldsförbud

De mänskliga rättigheterna har blivit allt mer centrala i den internationella rätten. Skyldigheten att upprätthålla dessa rättigheter står ibland mot icke-interventionsprincipen och analysen försvåras av en oenhetlig definition av begreppet. Folkrättsjurister och statspraxis har avgränsat och definierat interventionen olika och denna studie analyserar för dessa. Den här studien fokuserar på folkrHuman rights have become more central to international law. The obligation to maintain these rights are sometimes against the principal of non-intervention. The analysis of the intervention is hampered by different definition of the term. Experts in public international law and state practice has delimited and defined the humanitarian intervention differently and this study analyses these differe

Supportive housing residents’ experiences of the intervention active in my home

Background: The occupational therapy intervention, Active in My Home (AiMH), puts occupational engagement, participation in society and personal recovery in focus and includes increased staff support. Aims/Objectives: To investigate how the residents experienced the AiMH support, with a focus on their possibilities for engaging in occupations and participating in society after the intervention. Ma

Mästarlära - Om relationen lärare-elev i enskild musikundervisning

Title: The social relation between student & teacher in individual music education. The aim of this study is to examine the relevance of the social relation between teacher and student in instrumental tuition in non-compulsory music education. The method I have used is qualitative interview inspired by phenomenology. I have made interviews with four persons who have experienced individual sing

The Artisan Designer

This is a project about local small scale production, a story about how an artisan designer could take on the IKEAs of the world armed with modern day technology and some old fashioned hard work. This project is at its core a reflection about the future of design general and my role in particular. This contemplative journey does a few stops along the way to discuss the following sentence and wh

A2030 monthly Update 250513

Agenda 2030 Graduate School monthly newsletter #5 2025-05-13 Ylva van Meeningen Hi! First of all, a big shout out to Billy and Linn for successfully defending your thesis! Congratulations and we could not be more proud of you within the graduate school! This past week, Lund University has together with the municipality of Lund organized the Sustainability week. It is an annual event which organize

https://www.agenda2030graduateschool.lu.se/sites/agenda2030graduateschool.lu.se/files/2025-06/A2030_monthly%20update_250513.pdf - 2026-05-05

Role of Caveolae and miRNAs in Regulation of Urinary Bladder Function

The urinary bladder is responsible for storage and expulsion of urine. Proper urination depends on an ability of the bladder to adjust to increasing volume and to contract during micturition. A disturbance of bladder contractility may affect continence. In the present thesis I have used genetic, biochemical and physiological approaches to examine the role of caveolae and mircoRNAs in bladder funct

2024

1,2,3 Playtime. A lecture and workshop series in the field of games. 23 November 2023 to 3 October 2024 Pilot – Av jord är du kommen: Marika Hedemyr 12 December 2023 to 29 February 2024 IASPIS residency: Shitou & Ming 8 January to 31 March 2024 50% PhD seminar and documentation by Tanja Hylling Diers 18 & 19 January 2024 «Soleil-Journal» by Mariella Otto 24 to 28 January 2024 "Responding Arches" b

https://www.iac.lu.se/previous-projects/2024 - 2026-05-03