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Directed relation graph with error propagation (DRGEP) method combined with extensive validation for 0D, 1D and 2D CFD modeling supported by sensitivity and Rate-Of-Production (ROP) analyses are implemented for comparative study of detailed and reduced kinetic mechanisms for CH 4 + H 2 combustion. To this end, two detailed kinetic mechanisms, namely AramcoMech 2.0 and recently updated Konnov me
Air pollution is responsible for one in eight premature deaths worldwide, and thereby a major threat to human health. Health impact assessments of hypothetic changes in air pollution concentrations can be used as a mean of assessing the health impacts of policy, plans and projects, and support decision-makers in choices to prevent disease. The aim of this study was to estimate health impacts attri
The workshop will focus on what first-year students to higher education needs to be successful and how a peer learning programme might address those needs. (~5 min for introduction)The workshop will start with a brainstorm session where participants in small groups will share thoughts and ideas on the question (~20 min for activity): “What would you like to affect with your new students? Provide s
We discovered structurally novel human calcium-sensing receptor (CaSR) allosteric agonists and compared their pharmacology to phenylalkylamine calcimimetics. 1-Benzothiazol-2-yl-1-(2,4-dimethyl-phenyl)-ethanol (AC-265347) activated CaSR signaling in cellular proliferation and phosphatidylinositol (PI) hydrolysis assays with potencies of 30 and 10 nM, respectively. (S)-1-Benzothiazol-2-yl-1-(2,4-di
Coastal systems can act as filters for anthropogenic nutrient input into marine environments. Here, we assess the processes controlling the removal of phosphorus (P) and nitrogen (N) for four sites in the eutrophic Stockholm archipelago. Bottom water concentrations of oxygen (O2) and P are inversely correlated. This is attributed to the seasonal release of P from iron-oxide-bound (Fe-oxidebound) P
Background: Abdominal aortic aneurysm is associated with an increased mortality, mostly cardiovascular events. Moreover, aortoiliac calcification is associated with increased mortality in patients with peripheral occlusive disease. The aim of this study is to assess the potential association between iliofemoral calcification, assessed by calcium score, in patients undergoing infrarenal (endovascul
Background: The main objectives of this study were to evaluate the concordance between self-reported and registry-reported information regarding family history of breast cancer (BC), ovarian cancer (OvC) and other types of cancer in first-degree relatives of patients with early onset BC, and to determine the frequency of mutation carriers and non-mutation carriers. The secondary objective was to d
Popular Abstract in Swedish De mest briljanta ljuskällor som finns idag är de så kallade synkrotronljuskällorna som kan generera ljus över ett mycket brett våglängdsspectrum, från synligt ljus ända till mycket korta våglängder - röntgenstrålar. Det existerar många sådana faciliteter runt om i världen och de används dagligen i olika experiment för att öka våra kunskaper om material på en mikrospopiThere is a strong desire for short wavelength (~1 Å), short pulsewidth (<100 fs), high-brightness, transverse and longitudinally coherent light pulses for use by the synchrotron radiation community. These requirements exceed the limits achievable by existing, so-called, "third-generation" light sources, such as the Advanced Photon Source (APS) at Argonne National Laboratory (ANL), USA, the Europea
Inom kärnkraftsindustrin är säkerhet den aspekt som prioriteras högst. Alla kärnkraftverk är designade för att i högsta möjliga mån förhindra läckage av radioaktivetet till omgivningen, både under drift och i händelse av en allvarlig olycka. Med anledning av detta är reaktorinneslutningens vägg en av de viktigaste säkerhetsrelaterade konstruktionerna vid en anläggning, detta då denna konstruktionsSafety is the top priority at a nuclear facility. The nuclear power plants are designed to prevent radioactive leakage to the surroundings, both during normal operation as well as in case of a severe accident. One of the most important structures in a nuclear power plant, with regard to safety, is thus the reactor containment wall. The containment wall is the last main barrier to prevent radioacti
BACKGROUND: Both chronic obstructive pulmonary disease (COPD) and tuberculosis (TB) primarily affect the lungs and are major causes of morbidity and mortality worldwide. COPD and TB have common risk factors such as smoking, low socioeconomic status and dysregulation of host defence functions. COPD is a prevalent co-morbid condition, especially in elderly with TB but in contrast to other diseases k
Clinical trials of pharmaceuticals have been running in Russia for more than ten years and while it is an attractive location for research, it remains a largely untapped resource as researchers look to expand patient recruitment outside the Western world. While academic sites like Moscow, St Petersburg and Novosibirsk have all gained experience in clinical trials, smaller hospitals in peripheral
The uncertainties and sources of variation in projected impacts of climate change on agriculture and terrestrial ecosystems depend not only on the emission scenarios and climate models used for projecting future climates, but also on the impact models used, and the local soil and climatic conditions of the managed or unmanaged ecosystems under study. We addressed these uncertainties by applying di
Uppsatsen har genom en rättssociologisk undersökning granskat hur en lagändring gällande barnets behov av en god och nära kontakt med båda föräldrarna förhåller sig till barnets välmående i alla vårdnads-, boende -och umgängesmål. Lagändringen framförs i proposition 2024/25:10 tryggare hem för barn, som uppsatsen har redovisat för samt i betänkandet till propositionen. Lagändringen motiveras av enThe thesis has examined how a legislative change regarding the child's need of a good and close relationship with both parents relates to the child's well-being in all custody, residence, and contact matters. The legislative change is presented in the bill 2024/25:10 A Safer Home for Children, which the thesis has discussed, as well as the report accompanying the bill. The change is motiva
Nya byggnormer – smartare tunnlar? Cut-and-Cover-tunnlar är vanliga vid grund anläggningsnivå i svensk infrastruktur. Dessa betongkonstruktioner utsätts för konstant vattentryck, vilket ställer krav på sprickkontroll. Sprickor uppstår ofta på grund av tvångslaster, exempelvis från temperaturvariationer och krympning, när dessa deformationer hindras av omgivningen. För att begränsa sprickbildning dTunnel structures play an important role in Sweden’s infrastructure. At shallow depths, a common construction method is the so-called “Cut-and-Cover” tunnel, where the tunnel placement is excavated, cast in concrete on-site, and then backfilled. Such tunnels are typically subjected to constant water pressure, which yields high demands on crack control. Cracking in elongated concrete structures oft
Background. Climate change is the greatest threat to human health in the 21st century and healthcare contributes to approximately 5% of global greenhouse gas emissions. Intensive and perioperative care are particularly resource intensive. This thesis aimed to assess the climate and environmental impacts of perioperative and intensive care (Papers I–III) and to explore how environmental outcomes an
Xylanases without contaminating cellulases are produced by a wide variety of aerobic bacteria and fungi but anaerobic organisms producing such enzymes are rare. Clostridial species viz., Clostridium beijerinckii LU-1, C. acetobutylicum LU-1, C. butyricum and C. bifermentans LU-1 isolated from rumen produced xylanase (E.C. 3.2.1.8) of 1.5-4.2 U/ml on oat spelt xylan as sole carbon source. Cellulose
The last decades have seen a strongly increasing use of computers for modeling larger and more complex systems. This has been made possible by a combination of increasing computer power and easy-to-use graphical modeling environments and libraries of components. An important class of systems are described by initial value problems for dynamical systems, and the increasing size and complexity imply
BACKGROUND: There has been a growing body of evidence associating consumption of ultra-processed foods (UPF) with adverse health outcomes including depression, cardiovascular disease, all-cause mortality. However, whether UPF are associated with dementia is unknown. The authors investigated the associations between UPF and dementia incidence in UK biobank.METHODS: We included 72,083 participants (
Background: Umbilical cord clamping strategies at preterm birth have the potential to affect important health outcomes. The aim of this study was to compare the effectiveness of deferred cord clamping, umbilical cord milking, and immediate cord clamping in reducing neonatal mortality and morbidity at preterm birth. Methods: We conducted a systematic review and individual participant data meta-anal
