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OBJECTIVE: To investigate the effect on pregnancy outcome of integrating a comprehensive management plan for patients with type 1 diabetes (T1D) into the World Health Organization universal maternal care infrastructure. RESEARCH DESIGN AND METHODS: A comprehensive preconception-to-pregnancy management plan for women with T1D was implemented in 11 centers from 8 Chinese cities from 2015 to 2017. Se

Most patients with symptoms suggestive of chronic coronary syndrome (CCS) have no obstructive coronary artery disease (CAD) and better selection of patients to be referred for diagnostic tests is needed. The CAD-score is a non-invasive acoustic measure that, when added to pretest probability of CAD, has shown good rule-out capabilities. We aimed to test whether implementation of CAD-score in clini

Objectives: The aim of this study was to evaluate the short-term safety and efficacy of transcatheter aortic valve replacement (TAVR) with the LOTUS Edge system. Background: The LOTUS Edge system was commercially re-released in April 2019. The authors report the first European experience with this device. Methods: A multicenter, single-arm, retrospective registry was initiated to evaluate short-te

Introduction: The B-Natural study is a multicentre, multinational, observational study of haemophilia B (HB) designed to increase understanding of clinical manifestations, treatment and quality of life (QoL). Aim: To characterise and compare QoL in HB across disease severity groups and individuals with inhibitors to identify gaps in treatment. Methods: A total of 224 individuals from 107 families

Trötta ögon, huvudvärk, för kallt eller för varmt och allmänt lägre prestationsförmåga. Så kan det se ut på ett kontor med dålig ventilation och detta minskar förtjänsten för företaget samtidigt som det för de anställda upplevs påfrestande. Med ett väl dimensionerat, och rätt valt tilluftssystem blir inomhusklimatet avsevärt bättre och de anställda har de bästa förutsättningarna att med glädje preThis study compares the two traditional ventilation methods ; mixed ventilation and displacement ventilation, with a new type of dif fuser which attempts to solve the problem with blockage of the diffuser for the displacement ventilation. This new diffuser called Airshower is a product developed by Airson engineering AB whom is also the company where all simulations and tests for this study were

Denna studie undersöker utrymning genom inåtgående dörrar, något som bör undvikas enligt svenska byggregler när antalet personer i en lokal överstiger 30. Trots detta är de specifika utmaningarna och påverkande faktorerna, särskilt vad gäller personer med nedsatt rörelseförmåga, till stor del outforskade. För att belysa detta genomfördes en litteraturstudie samt utrymningsförsök med 36 deltagare (This study investigates evacuation through inward-opening doors, a practice discouraged by Swedish building regulations when occupant numbers exceed 30. Despite this, the specific challenges and influencing factors, particularly regarding individuals with movement impairments, remain largely unexplored. To address this gap, a literature review and eight evacuation scenarios involving 36 participan

Kvalitetskontrollsmodell för textilåtervinning 2025 infördes en EU-lag som gjorde det obligatoriskt att sortera textilavfall separat. Här presenteras grunden för en modell som relaterar reaktorparametrar till kvalité på återvunnen textilmassa. Textilindustrin omfattade 2024 knappt 2 biljoner USD. Det är en global industri där textilierna ofta designas i USA, produceras i asiatiska länder och slutTextile recycling is highly needed as great amounts of waste are produced every year and most of it is put into landfill or incinerated. This thesis lays the foundations for a quality control system which may be applied for controlling the recycling of cellulosic textiles in an upcoming pilot plant based on ShareTex’s technology. The quality control system was constructed as a mathematical model r

As a relatively new form of financial asset with unique properties, Bitcoin is increasingly included in portfolios to improve performance. However, research remains limited on how Bitcoin actually affects portfolio performance. This study aimed to broaden the field of research by exploring whether Bitcoin can improve portfolio performance during a global crisis. It sought to answer the question by

Människor strävar ofta efter att uppvisa en positiv fasad, både på sociala medier och i verkliga livet. Att undertrycka sina känslor och tvinga sig själv att vara positiv är något som i populärkulturen benämns som “toxic positivity”. Syftet med studien var att undersöka sambandet mellan ett undertryckande av känslor (suppression), enligt Gross (2002) emotionsregleringsmodell, och välmående. Vi strPeople often strive to exhibit a positive facade, both on social media as well as in real life. To suppress one's feelings and force oneself to be positive is something which in popular culture is referred to as “toxic positivity”. The aim of this study was to examine the relationship between suppression of feelings, or simply “suppression” according to the emotional regulation model formulate

According to efficient market theory, all publicly available information is reflected in asset prices. In its semi-strong form, fundamental analysis cannot be used as a method to generate an abnormal return. Implying that abnormal return can only be achieved by incurring a higher level of risk. Joel Greenblatt (2006) shows that by applying simple fundamental analysis and ranking companies based on

BACKGROUND: The implementation of COVID-19 vaccination among older persons at nursing homes has lowered the infection-associated mortality considerably, but emerging virus variants and decline in vaccine-induced immunity over time necessitate examination of future booster dosing strategies. The overall aim of this study was to assess vaccine protection against COVID-19 mortality in relation to tim

Importance: Emerging evidence suggests that cholesterol plays a role in breast cancer (BC) metabolism, raising the possibility that cholesterol-lowering medications, such as statins, may improve BC prognosis. Objective: To evaluate the association between postdiagnosis statin initiation and BC mortality using an emulated target trial approach. Design, Setting, and Participants: This observational

Background: This study aimed to assess chlamydia diagnostics in different clinic types, including internet-based self-sampling (IBSS). Furthermore, we investigated the incidence of chlamydia-associated complications. Methods: Data on Chlamydia trachomatis (CT) testing were retrieved from six healthcare regions in the years 2016–2023 across different categories of testing facilities. National data

PurposeTürkiye ranks among the highest in antibiotic consumption within OECD countries and faces growing challenges from multidrug-resistant uropathogens. Nationwide, resistance-guided treatment data remain scarce. The main objective of this work is to provide a comprehensive nationwide data on antibiotic resistance patterns among uropathogens to guide treatment options in urinary tract infections

Cell-mediated immune suppression may play an important role in lung carcinogenesis. We investigated the associations for circulating levels of tryptophan, kynurenine, kynurenine:tryptophan ratio (KTR), quinolinic acid (QA) and neopterin as markers of immune regulation and inflammation with lung cancer risk in 5,364 smoking-matched case–control pairs from 20 prospective cohorts included in the inte

Background: The mandibular symphysis is a true joint with a fibrocartilage disc stabilizing both ramus of mandible. The mandibular fracture occurs in 15% of all cases of fracture in cats, and of these, 73% correspond to fracture of the mandibular symphysis. There is a technique for stabilization of symphysis fracture using a nylon cable tie band, however it is necessary to perform two lateral inci

The purpose of the present study was to examine the potential effectiveness of a group cognitive-behavioral therapy (CBT) for adults with attention-deficit hyperactivity disorder (ADHD) with residual significant clinical symptoms after being stabilized on medication. All adult patients with ADHD in an outpatient psychiatric clinic who had been stabilized on medication but still showed clinical sig

Åklagarens objektivitetsplikt har under de senaste åren blivit särskilt uppmärksammad med anledning av Thomas Quick-fallet. Under 90-talet erkände Quick ett 30-tal mord, varav han blev dömd för åtta av dem. Emellertid förändrades allt år 2008 när Quick tog tillbaka sina erkännanden. Detta ledde till ett antal omprövningar, där han så småningom blev friad från samtliga åtal. I såväl domstolar som m

Reliable methods for estimating financial return volatility are crucial in many areas of trading and investing. Two such frameworks, the GARCH and SV, have been of particular interest to academics and practitioners alike. The GARCH model describes the variance of the current innovation as a function of the actual sizes of the previous innovations. In contrast, the stochastic volatility model descr

This dissertation investigates the function of the sea in contemporary British and Irish literature, focusing on the following three novels: Dermot Bolger’s Temptation (2000), John Banville’s The Sea (2005), and Ian McEwan’s On Chesil Beach (2007). The analysis is divided into two main parts, where the sea is considered in its roles as a setting and as a symbol. The former section starts with a su