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Investigation of Cerebral Mitochondrial Injury in a Porcine Survivor Model of Carbon Monoxide Poisoning

Introduction: Carbon monoxide (CO) is a colorless and odorless gas that is a leading cause of environmental poisoning in the USA with substantial mortality and morbidity. The mechanism of CO poisoning is complex and includes hypoxia, inflammation, and leukocyte sequestration in brain microvessel segments leading to increased reactive oxygen species. Another important pathway is the effects of CO o

The epidemiology and outcomes of acute kidney injury following orthopaedic procedures : A retrospective cohort study

Background: Acute kidney injury (AKI) is a serious complication following major surgery. This study examined the incidence and risk factors of AKI following orthopaedic surgeries in an Icelandic cohort, as well as the association between AKI and patient- and surgery-related factors. Methods: This retrospective cohort study comprised all patients 18 years and older who underwent orthopaedic surgeri

Paediatric Acute-onset Neuropsychiatric Syndrome (PANS) and intravenous immunoglobulin (IVIG) : comprehensive open-label trial in ten children

BACKGROUND: Treatment with intravenous immunoglobulin (IVIG) in children with Paediatric Acute-onset Neuropsychiatric Syndrome (PANS) has for many years been used on clinical indications, but the research evidence for its efficacy is insufficient.METHODS: Open-label prospective in-depth trial including ten children (median age 10.3 years) with PANS, who received IVIG treatment 2 g/kg monthly for t

Understanding information sharing in supply chains - Identifying contingency factors that impact benefits of information sharing

För att öka vår förståelse av informationsdelning i försörjningskedjor så är studiens syfte trefaldigt: att granska och analysera existerande akademisk litteratur för att beskriva och strukturera forskningsområdet; att empiriskt utforska informationsdelning i en försörjningskedja som representerar mer än tre led; och att utforska kontextuella faktorer genom litteraturgenomgång och empirisk datainsTo increase our understanding of information sharing in supply chains the purposeof this licentiate was threefold: to review and analyze existing academic literature to describe and structure the research field; to empirically explore information sharing in a supply chain representing more than three tiers; and to explore contingency factors through literature reviews and empirical data collection

Neutralizing antibodies and efficacy of interferon beta-1a - A 4-year controlled study

Objective: To determine the incidence and clinical significance of neutralizing antibody (NAb) formation in patients with relapsing multiple sclerosis ( MS) who participated in the European Interferon Beta-1a IM Dose-Comparison Study. Methods. Patients were randomized to treatment with interferon beta-1a (IFN beta-1a) 30 mu g or 60 mu g IM once weekly for up to 4 years. Serum samples obtained at b

Interface characterization of metal-HfO2-InAs gate stacks using hard x-ray photoemission spectroscopy

MOS devices based on III-V semiconductors and thin high-k dielectric layers offer possibilities for improved transport properties. Here, we have studied the interface structure and chemical composition of realistic MOS gate stacks, consisting of a W or Pd metal film and a 6- or 12-nm-thick HfO2 layer deposited on InAs, with Hard X-ray Photoemission Spectroscopy. In and As signals from InAs buried

Correlations between polarisation states of W particles in the reaction e(-)e(+)-> W-W+ at LEP2 energies 189-209 GeV

In a study of the reaction e(-)e(+)-> W-W+ with the DELPHI detector, the probabilities of the two W particles occurring in the joint polarisation states transverse-transverse (T T), longitudinal-transverse plus transverse-longitudinal (LT) and longitudinal-longitudinal (LL) have been determined using the final states WW -> lvq (q) over bar (l = e, mu). The two-particle joint polarisation probabili

Reference data representative of normal findings at three-dimensional power Doppler ultrasound examination of the cervix from 17 to 41 gestational weeks.

Objectives To develop normal reference ranges for cervical volume and vascular indices using three-dimensional (3D) power Doppler ultrasonograpby from 17 to 41 gestational weeks. Methods This was a cross-sectional study of 352 nulliparous and 291 parous women who delivered at term and underwent transvaginal 3D power Doppler ultrasound examination of the cervix once at 17 to 41 weeks' gestation. We

Det du inte vet mår du dåligt av: En experimentell studie av uppmärksamhets bias hos ångestindivider

Syftet med den här studien var att undersöka ångests påverkan på uppmärksamhet. Deltagare med högt skattad ångest förväntades skilja sig åt från deltagare med lågt skattad ångest gällande deras uppmärksamhet. Deltagare förväntades skapa ett implicit minne för kombinationen av ansikten som presenterades för dem i experimentet. Ett modifierat dote probe test användes för att undersöka vad försöksperThe purpose of this study was to examine attentional biases in anxiety. Participants with high self-rated anxiety were predicted to differ in their attention compared to participants with low self-rated anxiety. Participants were predicted to have an implicit memory for the combination of faces that were used in the study. A modified dot probe task was used to examine high and low social and/or tr

Tills döden skiljer dem åt - en studie om arvsrätten mellan makar

Syftet med denna uppsats är att studera hur efterlevande makes arvsrätt och andra ekonomiska skyddsregler vid händelse av den ena makens död är uppbyggda. Syftet är även att ur ett genusperspektiv analysera denna lagstiftning för att på så sätt få en djupare förståelse för varför reglerna är konstruerade på detta specifika sätt. För att kunna diskutera genusaspektens påverkan på den svenska lagstiThe purpose of this paper is to study how the surviving spouse’s inheritance rights and other financial guarantees in case of death of the other spouse are constructed and from a gender perspective’s analyse this legislation in order to gain a deeper understanding of why the rules are designed in this specific way. In order to discuss the gender perspectives impact on the Swedish law it’s importan

Evaluation of Long-term Impact of Coal Mining in Zambezi River Basin in Mozambique

Zambezi River Basin is an international river basin which sustains life of about 30 million people in its riparian countries: Angola, Botswana, Malawi, Mozambique, Namibia, Tanzania, Zambia and Zimbabwe. The main stream of the river enters to Mozambique with average flow of about 2330 m3/s and reaches the outfall in the Indian Ocean with about 4134 m3/s. This makes both the activities in the upstr

Digital psycho-prophylactics: a pilot study on how pregnant women navigate through a virtual delivery ward

INTRODUCTION AND AIM Virtual Visit Tool is a computer tool containing a total documentation of the delivery ward of Ystad Hospital in Sweden. Virtual Visit Tool places the user within a photo-realistic simulation of the delivery ward. This pilot study has two aims: 1) to analyse how pregnant women walk through the virtual delivery ward and to see what catches their attention during the virtual wal

Utvärdering av "30 aspekter" En kvalitetskontroll av ett personlighetstest grundat på femfaktormodellen

The purpose of this investigation was to evaluate the personality questionnaire 30 aspects, which is based on the five-factor model. Our aim was to investigate the properties of the questionnaire through explorative factor analysis and reliability ratings. We also set out to explore the factor structure of the test to decide whether the instrument agreed with the five-factor model or not. The ques

Soft tissue response to the presence of polypropylene-g-poly(ethylene glycol) comb-type graft copolymers containing gold nanoparticles

The aim of this study is to evaluate the soft tissue response of the pure and Au-embedded PPg-PEG. PP-g-PEG2000, PP-g-PEG4000, Au-PP-g-PEG2000, and AuPP-g-PEG4000 were obtained via chlorination of polypropylene and polyethylene glycol in the presence of a base with a "grafting onto" technique. Solvent cast films of these four copolymers with PP as a control group were embedded into five different

Clinical impact of breakpoint position within M-bcr in chronic myeloid leukemia

We have analyzed the M-bcr breakpoint position in 133 Philadelphia-positive chronic myeloid leukemia patients and correlated the findings with clinical, hematologic, and cytogenetic data. We also investigated the splicing pattern of the BCR-ABL mRNA in 30 patients, using reverse transcriptase PCR. No statistically significant differences were found between breakpoint position within M-bcr and clin

Is bone mineral density advantage maintained long-term in previous weight lifters?

This cross-sectional study was done in order to ascertain whether there is a lifelong beneficial effect on bone mineral density (BMD) of early, long-lasting, and intense physical exercise. Forty-eight male ex-weight lifters, mean age 64 years (range 50-79) participated. They had followed a training program of an average of 10 hours/week (range 4-20) for an average of 13 years (range 1-34). They ha

Asian Models of Agricultural Development and their Relevance to Afrika

This working paper discusses the different Asian experiences of the Green Revolution from the late 1960s to the 1980s in the perspective of earlier developments of agricultural intensification. The intention of the paper is to identify common features and conditions contributing to the considerable success of Asian agriculture over the past 30 years. The authors argue that the Green Revolution mus

Occurrence of the hermit beetle (Osmoderma eremita), in Sweden.

We have compiled data on the occurrence of a threatened beetle, Osmoderma eremita, in Sweden. The species inhabits tree hollows with wood mould. The data were compiled from field surveys conducted in 1993-2003, using pitfall traps at 401 localities and using wood mould sampling at 104 localities. We have also gone through published data and all larger Swedish museums and registered old records. O.

Perceived anxiety, depression, and sleeping problems in relation to psychotropic drug use among elderly in assisted-living facilities.

Objective: The aim of the present study was to investigate the perceived anxiety, depression, sleeping habits, and participation in social activities in relation to psychotropic drug use among elderly in assisted-living facilities and to identify factors of importance for the use of these drugs. Method: The study had a cross-sectional design and included 93 residents living in old-age homes or in