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Introduction: Misoprostol (Cytotec) was primarily made for treating gastric ulcers. However today it is mostly used for abortion, treating postpartum hemorrhage, and for induction of labor. The tablet contains 200 µg of misoprostol, yet the dosages used for induction of labor are much smaller (25–50 µg), leading to uncertainty of dosage in daily use. Aim: To evaluate and compare the relative bioav

Background: Papillary thyroid cancer is treated with total/near-total thyroidectomy (TT) with or without central lymph node dissection (CLND), depending on risk factors and tumour size. Balancing the risk of disease recurrence and surgical morbidity remains a challenge. A population-based nationwide study was undertaken to evaluate the risk of permanent hypoparathyroidism associated with CLND. Met

Objectives: An observed variation in the risk of celiac disease, according to the season of birth, suggests that vitamin D may affect the development of the disease. The aim of this study was to investigate if vitamin D concentration is associated with the risk of celiac disease autoimmunity (CDA) in genetically at-risk children. Study Design: Children prospectively followed in the multinational T

BACKGROUND: Hand eczema is more common in healthcare workers compared to the general population. The hands are subject to changing occupational exposures due to mandatory hygiene regulations for health care workers.OBJECTIVES: To describe the exposure due to hygiene procedures and investigate the associations between occupational hand washing, use of non-sterile gloves, and hand disinfectant and s

Infant mortality is a powerful indicator to measure the health and social status of a country. The purpose of this study is to identify the important factors that in uence the infant mortality of Bangladesh. Moreover, this study suggests the government and the policy makers to improve the health and social sectors for reducing the country's infant mortality signicantly. To investigate the impo

This Master thesis work was performed in Ericsson AB, Lund. It studies and validates two classes of algorithms to be used in mm-wave massive MIMO antenna arrays, for their use in the future 5G mobile communication systems. The first class of algorithms relates to the calibration of the transceiver (TRX) chains responses of the antenna array and makes use of the antenna array mutual coupling, which

This thesis explores a new source of sexual education, which some express concerns about and others are not worried about it at all. The source is social media. Whereas before, young individuals could use informal sources such as friends, family, the media or formal sources such as doctors, teachers, and other health workers. Now young individuals can log on to Facebook, Instagram, YouTube, TikTok

PURPOSE: A Swedish and Norwegian study was designed to examine health-related quality of life (HQL) in patients with head and neck cancer (head and neck) at diagnosis and during treatment and rehabilitation. The overall aim was to examine the impact on HQL at diagnosis depending on tumor location, stage, sex, and age (part I) and to describe HQL longitudinally and determine for which patients and

The high fat-fed mouse is an experimental model for studies of islet dysfunction as a mechanism for glucose intolerance and for evaluation of therapeutic targets. This model is, however, dynamic with a temporal and dietary fat content-dependent impact on islet function and glucose tolerance, the details of which are unknown. This study therefore examined the time course of changes in the insulin r

The reliable operation of nuclear reactors is contingent upon precise control mechanisms for critical components, such as the head circulation pumps. This master thesis investigates an innovative approach to address the ramp-down speed of these pumps during external electrical grid failures by exploring the application of a supercapacitor group. Presently, the existing solution relies on a fly-whe

Today, buildings account for approximately 30% of worldwide energy use, with HVAC (Heating, Ventilation, and Air Conditioning) systems representing nearly 40% of that total. Improving the energy efficiency of HVAC systems is therefore essential for reducing operational costs and mitigating environmental impact. Because HVAC systems operate continuously and under strict operational constraints, acc

I juli 2023 tillsatte regeringen en utredning i syfte att genomföra en övergri- pande översyn av straffskalorna samt lägga fram förslag till ett reformerat och mer rättvist påföljdssystem. Regeringen framhåller i direktivet att straffsyste- met bör uttrycka en tydligare klandervärdering av brottsliga gärningar för att undvika att brottsoffer upplever rättsprocessen som ytterligare en kränkning. DeIn July 2023, the Swedish government appointed an inquiry with the purpose of conducting a comprehensive review of the penalty scales and presenting proposals for a reformed and fairer penalty system. The government empha- sizes in the directive that the penal system should express a clearer condem- nation of the blameworthiness of criminal acts in order to avoid that victims experience the legal

Individuals with immigrant background generally perform less well in school than non-immigrants. Performing well in school may decrease the risk of substance use disorder (SUD). We investigated whether higher school performance is associated with a decreased risk of SUD in early adulthood among immigrants and non-immigrants and whether subsequent educational attainment and employment status partly

Differences in technological traditions we find between Neanderthals and anatomically modern humans has long been debated. It is important to discuss whether the differences in the handling of flint and other raw materials between the two populations . The use of raw materials are obviously directly related to the production of tools used to acquire food . Besides the quality of the material, also

OBJECTIVE: To examine the clinical phenotype, gray matter atrophy patterns, and small vessel disease in patients who developed prodromal or probable Alzheimer disease dementia, despite carrying the protective APOEε2 allele. METHODS: We included 36 β-amyloid-positive (by CSF or PET) APOEε2 carriers (all ε2/ε3) with mild cognitive impairment or dementia due to Alzheimer disease who were matched for

Purpose: Whey protein (WP) consumption prior to a meal curbs appetite and reduces postprandial glucose (PPG) through stimulating endogenous GLP-1 secretion and insulin. Methods: We assessed the metabolic effects of a concentrated WP, using a new micelle-technology (WPM), in people with type 2 diabetes (T2D) and overweight or obesity (NCT04639726). In a randomized-crossover design, participants per

This paper studies the possibility to exploit linear dependence in stock returns of the Swedish OMX 30 index. The main model studied in the paper is a Vector autoregressive (VAR) model. Ten years of data from the OMX 30 index is used, consisting of 27 stocks for the period 2006-2015 which is transformed into daily, weekly and monthly returns. First the significance of the models is tested and it i

During the last few years, crowding effects on the physics of proteins has become an increasingly popular topic of research. This is is because most biological processes involving proteins naturally take place in a crowded environment, e.g. in the cellular environment where macromolecules may occupy 30% of the volume. One such biological process would be the formation of amyloid aggregates, which

Den svenska successionsrätten innefattar en rätt för bröstarvingar att erhålla en laglott. Bestämmelserna har blivit anklagade för att vara föråldrade och har varit omdebatterad såväl i media som i riksdagen. Följande uppsats kommer att undersöka om laglotten har blivit föråldrad och utröna vilka argument som kan tänkas motivera ett bibehållande av lagstiftningen. Syftet är att se hur gällande rätThe Swedish law of succession includes a right for the direct heir to retain a part of the heritage if the deceased have drawn a will. This phenomenon is called statutory share of inheritance (in Swedish: laglott). The regulations have been accused of being out-of-date and have been up for debate in both media as well as in the parliament. Following essay will examine if the statutory share is out

How mice avoid diseases, a measure of divergence The response we have to diseases vary from person to person. In much the same way diseases affect and are battled in many different ways depending on the species. This happens due to differences in their immune system. So, what causes these differences? Well, they are mostly caused by differences in the DNA, the molecule which has the code for ever