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Many companies today are transforming their development process by leaving an old-fashioned one, like the waterfall model, behind and instead aiming for a modern process like Scrum that can keep up with today’s rapid market changes and reduce time to market lag. These companies are often aiming to become more agile and with this comes a need for short release cycles in order to get fast feedback a
Food consumption is one of the main areas of concern if we should become successful in creating a sustainable future. However, there are diverse views on what sustainability is, and consumers have varied knowledge and commitment to consuming sustainable food. The aim of this thesis is to investigate the impact of consumer understanding of food labels on sustainable purchase behaviour and to explor
Det svenska kontradiktoriska tvistemålsförfarandet bygger på tanken att parterna har det primära ansvaret för att lägga fram bevisning till stöd för sin talan. Ett undantag till den här principen finns i regeln om processuell edition i 38 kap. RB, vilket gör det möjligt för en part att framtvinga skriftliga handlingar som innehas av motparten och kan ha betydelse som bevis i en pågående tvist. FörCivil proceedings under Swedish law are based on the adversarial principle which means that the litigants have the primary responsibility for presenting evidence that supports their case. In Chapter 38 of the Swedish Code of Judicial Procedure there is an exception to this principle. It enables parties in an ongoing civil litigation to gain access to written evidence that is in the possession of t
Background: Autism spectrum disorders (ASD) are severe neurodevelopmental disorders with the male:female ratio of 4:1, implying the contribution of X chromosome genetic factors to the susceptibility of ASD. The ribosomal protein L10 (RPL10) gene, located on chromosome Xq28, codes for a key protein in assembling large ribosomal subunit and protein synthesis. Two non-synonymous mutations of RPL10,
Objective: To assess the prevalence and risk factors of emergency peripartum hysterectomy. Design:Nordic collaborative study. Population605362 deliveries across the five Nordic countries. Methods: We collected data prospectively from patients undergoing emergency peripartum hysterectomy within 7days of delivery from medical birth registers and hospital discharge registers. Control populations cons
Parkinson's disease (PD) is a multifactorial movement disorder characterized by progressive neurodegeneration. Genome-wide association studies (GWAS) have nominated over fifteen distinct loci associated with risk of PD, however the biological mechanisms by which these loci influence disease risk are mostly unknown. GWAS are only the first step in the identification of disease genes: the specific c
Background: Proteolytic Clostridium botulinum is the causative agent of botulism, a severe neuroparalytic illness. Given the severity of botulism, surprisingly little is known of the population structure, biology, phylogeny or evolution of C. botulinum. The recent determination of the genome sequence of C. botulinum has allowed comparative genomic indexing using a DNA microarray. Results: Whole ge
We have estimated the hydration free energy for 20 neutral drug-like molecules, as well as for three series of 6-11 inhibitors to avidin, factor Xa, and galectin-3 with four different continuum solvent approaches (the polarised continuum method the Langevin dipole method, the finite-difference solution of the Poisson equation, and the generalised Born method), and several variants of each, giving
Context: Prostate cancer (PCa) is one of the most common human malignancies and arises through genetic and epigenetic alterations. Epigenetic modifications include DNA methylation, histone modifications, and microRNAs (miRNA) and produce heritable changes in gene expression without altering the DNA coding sequence. Objective: To review progress in the understanding of PCa epigenetics and to focus
Background and purpose: There is an urgent need to improve patient-selection to surgical treatment in advanced ovarian cancer as our results showed that cytoreductive surgery was without effect or even detrimental in a yet unknown subgroup of women. With an ageing population, 30% of women with advanced ovarian cancer in Sweden are >75 years. Nevertheless, there are no recommendations on patient-se
BACKGROUND: Although death in old age is unavoidable, premature death-defined here as death before age 70 years-is not. To assess whether halving premature mortality by 2050 is feasible, we examined the large variation in premature death rates before age 70 years and trends over the past 50 years (1970-2019), covering ten world regions and the 30 most-populous nations. This analysis was undertaken
Ladyfest Sweden is a cultural festival which aims to create a cultural space of expression for women, thus the artists and the organizers are women. It is organized by three different groups in three different cities: Malmö, Stockholm and Göteborg. This thesis is focused on Ladyfest Malmö, all the field work being realized with this group. We tried to include this phenomenon in a global and a part
We investigated the vertical distribution, storage, landscape partitioning, and spatial variability of soil amorphous silica (ASi) at four different sites underlain by continuous permafrost and representative of mountainous and lowland tundra, in the circum-Arctic region. Based on a larger set of data, we present the first estimate of the ASi soil reservoir (0-1 m depth) in circum-Arctic tundra te
Aims: Resuscitated out-of-hospital cardiac arrest (OHCA) patients who remain comatose after hospital arrival are at high risk of mortality due to anoxic brain injury. MicroRNA are small-non-coding RNA molecules ultimately involved in gene-silencing. They show promise as biomarkers, as they are stable in body fluids. The microRNA 9-3p (miR-9-3p) is associated with neurological injury in trauma and
Deficiency in C1 inhibitor (C1INH, SERPING1) is canonically associated with hereditary angioedema (HAE-C1INH) but not thrombosis. To determine the thrombosis risk conferred by loss of C1INH in the general population, we studied genetically-defined C1INH deficiency across 635,823 participants. Functionally deleterious germline coding variation in SERPING1 was rare (~1:10,000), indicating strong gen
Background: The existence of a “minority tax,” defined as the burden of extra responsibilities placed on minorities relative to non-minorities of the same position, has been documented across various fields, including and beyond medicine. This study sought to quantify the types and extent of the minority tax faced by minority orthopaedic surgeons, as well as evaluate the degree to which this work
MOTIVATION: Missing data present a pervasive challenge in data analysis, potentially biasing outcomes and undermining conclusions if not addressed properly. Missing data are commonly classified into Missing Completely at Random (MCAR), Missing at Random (MAR), and Missing Not at Random (MNAR). While MCAR poses a minimal risk of data distortion, both MAR and MNAR can seriously affect the results of
Objectives: Real-world evidence is needed to inform treatment strategies for patients with PsA and axial SpA (axSpA) who have non-musculoskeletal manifestations (NMMs), various risk factors and comorbidities. International collaboration is required to ensure statistical power and to enhance generalizability. The first step forward is identifying which data are currently being collected. Across 17
Matris/lathund för val av anställningstyp i förhållande till anställningsform och avtal Anställningsform (grund) Typ av anställning (ansttyp) Avtal Kommentar/förklaring Övrigt Tillsvidare 4 § LAS Lön, individuell (tillsvidare) Villkorsavtal eller villkorsavtal -T. Det senare används för arbetstagare tillhörande SACO/S (tillsvidareavtal) Tillsvidareanställning | HR-webben (lu.se) Tidbegränsad, Särs
Kursguide - Course Syllabus • • • • • • Details of approval The syllabus was approved by The Master's Programmes Board on 2016-12-15 to be valid from 2017-01-01, autumn semester 2017. General Information The course is a compulsory component of the Bachelor of Medical Science programme in Biomedicine and is included in semester 5. Language of instruction: English Learning outcomes Knowledge and und
https://www.medicine.lu.se/sites/medicine.lu.se/files/bima82.pdf - 2026-06-04
