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Reproductive function in male childhood cancer survivors

Popular Abstract in Swedish Populärvetenskaplig sammanfattning Målet med denna avhandling var att undersöka hur cancersjukdomar i barndomen och behandlingen av dessa påverkar olika aspekter av fortplantningsförmågan i vuxen ålder. Glädjande nog har andelen patienter som överlever cancer i barndomen de senaste decennierna ökat stadigt till nivåer som idag ligger på nästan 80%. Ökad överlevnad medfChildhood cancer (CC) survival rate has increased over the last couple of decades, today approaching 80%. Therefore more attention has been paid to late effects. One important issue for CC survivors (CCS) is impaired reproductive function. CC per se and/or its treatment can impair the reproductive ability by affecting sperm production, as well as by damaging sperm DNA. This is a matter of concern,

The Pancreatic Tumour Microenvironment. Influence by macrophages and glucose levels on tumourigenesis.

Pancreatic cancer is the fourth cause of cancer-related death with a 5-year survival rate less than 5%. Two of the risk factors are chronic pancreatitis and type 2 diabetes (T2D), which are believed to promote the tumour progression. Pancreatic cancer and its tumour microenvironment is characterised by a dense stroma, immune cell infiltration and poor vascularisation. This creates a favourable env

A LEAP Forward in Wildlife Conservation : A Standardized Framework to Determine Mortality Causes in Large GPS-Tagged Birds

Anthropogenic activities threaten many wildlife populations by increasing mortality rates, making it crucial to identify the locations and causes of mortality to inform conservation actions. Technological advancements, such as GPS satellite tracking, enable precise recording of wildlife movements. High-resolution data from such devices can facilitate rapid carcass recovery and provide insights int

Inhibitors of Human and Malaria Parasite Dihydroorotate Dehydrogenase

Popular Abstract in Swedish Pyrimidiner är DNA-byggstenar som är essentiella för cellens överlevnad och delning. I mänskliga celler finns pyrimidiner att tillgå antingen genom återupptag eller genom biosyntes (nysyntes). Biosyntesen av pyrimidiner sker i flera steg och i ett av dem spelar enzymet Dihydroorotat dehydrogenas (DHODH) en avgörande roll genom att katalysera en oxidationsreaktion. När cIn the first part of the PhD work, small chemical entities (fragments) found to inhibit human dihydroorotate dehydrogenase (DHODH), were chemically optimized. As part of an ample program at Active Biotech to find new drugs against autoimmune diseases, expanded fragments were repeatedly designed, synthesized and evaluated in a human DHODH assay. Potent inhibitors were identified within three classe

Immunohistochemical study of rats receiving peripheral immunization with IFNg transfected glioma cells

Popular Abstract in Swedish Vi har studerat hur man kan använda immunsystemet för att behandla råttor med hjärntumör (maligna gliom). Eftersom råttor väldigt sällan utvecklar hjärntumörer, så måste vi injicera tumörceller i hjärnan själva. Om djuren inte får någon behandling dör de vanligen inom ca. 24 dagar. Får de däremot en injektion i buken eller under huden på benet med genmanipulerade tumörcMalignant glioma is, with rare exceptions in younger adults, an uncurable brain tumor, as very few survive more than 1-2 years after diagnosis. Despite advances in recent years, current treatments such as surgery, radiotherapy and chemotherapy only prolongs the life of the patients. Because of the poor prognosis, several additional therapies have been investigated and are under development, such a

”Är det detta du menar? – Nej, det är det verkligen inte!” En analys av konsumenters missnöje vid möten med chatbots i kundtjänst

Chatbots are increasingly being adapted as substitutes to humans in customer service. As the level of adoption increases, it becomes more important to understand the phenomenon of robots replacing humans – a new chapter in the rising digital world. Earlier research has explored and aroused criticism against the trend of automation and digitalization, urging companies to move towards a more customeAbstract Title: ”Is this what you mean? – No, it really isn't!” – An analysis of consumers' dissatisfaction in encounters with chatbots in customer service Seminar date: January 10th, 2024 Course: FEKH29, Business Administration: Bachelor Degree Project in Marketing Undergraduate Level, 15 ECTS-credits Authors: Emma Axelsson, Annie Bolmgren and Julia Krusell Advisor: Sofia Ulver Keywords:

Assessing ozone exposure for epidemiological studies in Malmo and Umea, Sweden

Ground level ozone [ozone] is considered a harmful air pollutant but there is a knowledge gap regarding its long term health effects. The main aim of this study is to develop local Land Use Regression [LUR] models that can be used to study long term health effects of ozone. The specific aim is to develop spatial LUR models for two Swedish cities, Umea and Malmo, as well as a temporal model for Mal

THE ROLE OF DENDRITIC CELLS AND TYPE I INTERFERON IN THE GENERATION AND FUNCTION OF T FOLLICULAR HELPER CELLS

Popular Abstract in Swedish Immunförsvaret har till uppgift att skydda kroppen mot främmande mikroorganismer såsom bakterier och virus. En rad olika celler, vävnader samt organ samarbetar för att utforma ett väl fungerande immunförsvar. Det är ytterst viktigt att immunförsvaret känner igen kroppsfrämmande ämnen (antigen), som till exempel bakterieceller, men också att det skiljer dessa från kroppsGeneration of long-lived plasma cells and memory B cells of high affinity takes place in germinal centers and depends on help from a specialized CD4+ T cell subset termed T follicular helper (Tfh) cells. These processes are crucial for long-term protection upon natural infection or in settings of vaccination, however they are also responsible for development of antibody-mediated autoimmune disease

Morphological alterations in frontotemporal dementia:

Popular Abstract in Swedish Frontotemporal demens är ett sjukdomstillstånd där nervceller i hjärnans pann- (“fronto”) och tinninglober (“temporal”) förtvinar, vilket leder till en tilltagande cellförlust och uttunning av hjärnbarken i dessa områden. Till skillnad från Alzheimers sjukdom, den vanligaste demenssjukdomen, leder frontotemporal demens i första hand inte till försämrat minne och orienteThe present thesis explores alterations in brain morphology in the neurodegenerative disorder of frontotemporal dementia (FTD). With the aim to improve the clinical diagnostics of FTD, we explored the diagnostic potential of measuring morphological alterations in the white matter by diffusion tensor imaging (DTI)- MRI, compared with the more commonly used assessment of grey matter thickness and vo

Analysis of factors of importance for drug use

Background: There are differences in drug use depending on non-medical factors such as age, gender and socioeconomic status. The combined effect of these factors, with adjustment for multimorbidity, is highly relevant to study to ensure equality in drug use. Objectives: 1. To examine drug use related to age, gender, income and education after adjustment for multimorbidity, in an entire adult popul

Följebrev Uppdaterade Villkor För Statens Tjänstereseförsäkring Samt Reseförsäkring 2023

Sid 1 (5) 2023-09-01 Dnr 28.3.3-7914 & 7915- 2023 Följebrev villkorsrevidering POSTADRESS 651 80 Karlstad TELEFON 054-22 12 00 växel E-POST forsakring@kammarkollegiet.se BANKGIRO 5052-5740 BESÖKSADRESS Våxnäsgatan 10, Karolinen TELEFAX 054-15 56 10 INTERNET www.kammarkollegiet.se Uppdaterade villkor för Statens tjänstereseförsäkring samt Reseförsäkring Kammarkollegiet har reviderat villkoren för S

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2023-11/F%C3%B6ljebrev%20uppdaterade%20villkor%20f%C3%B6r%20Statens%20tj%C3%A4nsteresef%C3%B6rs%C3%A4kring%20samt%20Resef%C3%B6rs%C3%A4kring%202023.pdf - 2026-05-07

Bjurkell ulrika

,. LUND UNIVERsrtY LUND UNIVERSITY MASTER'S PROGRAMME IN ENVIRONMENTAL SCIENCE WHEN'S DINNER READY? -An Evaluation of Community Gardening and its Contribution to A Sustainable Food System MASTER'S THE SIS Prepared by: Ulrika Bjurkell 3-505 Cranbrook rd., London, On P.O Box 28075 Canada E-mail: ulrikabjurkell@hotmail.com Supervised by: Carina Borgstrom-Hansson Departmentof HumanEcology Universityof

https://www.lumes.lu.se/sites/lumes.lu.se/files/bjurkell_ulrika.pdf - 2026-05-07

FYSC12 CourseEvaluation VT2021

FYSC12 course evaluation spring 2021 Postal address Box 118, 22100 Lund, Visiting address Professorsgatan 1, 22363 Lund. Telephone +46 46 222 7633, +46 46 222 00 00 E-mail Dirk.Rudolph@nuclear.lu.se Website http://www.nuclear.lu.se Depar tment o f Phys ics Div is ion of Nuc lear Phys ics Prof . D i rk Rud o lph Course Evaluation FYSC12, VT21 During the introduction of the VT21 lecture series, two

https://www.fysik.lu.se/en/sites/fysik.lu.se.en/files/2021-04/FYSC12%20CourseEvaluation%20VT2021.pdf - 2026-05-07

Sara hallin

“Meet the nitrous oxide reducing microbes in soils and sediments” Mitigating N2O emissions - an ES delivered by soil microbes Sara Hallin Dept. Forest Mycology & Plant Pathology Swedish University of Agricultural Sciences, Uppsala ClimBEco Annual Meeting Aug 24-25, 2017 Höllviken « the microbial zoo » Biomass in soil: 10 ton/ha • Bacteria 1-2 ton Bacteria occupy <0.3% of pore space Fungi: 10 – 100

https://www.cec.lu.se/sites/cec.lu.se/files/sara_hallin.pdf - 2026-05-07

Instructions And Procedures For Programme Evaluations By External Experts At The Faculty Of Social S

Instructions and procedures for programme evaluations by external experts at the Faculty of Social Sciences Page 1 of 16 Faculty Board DECISION Reg. No. STYR 2021/117 2021-02-04 Instructions and procedures for programme evaluations by external experts at the Faculty of Social Sciences This decision enters into force on 4 February 2021 and replace and invalidate the previous decision on Instruction

https://www.sam.lu.se/en/internal/sites/sam.lu.se.en.internal/files/2021-03/Instructions%20and%20procedures%20for%20programme%20evaluations%20by%20external%20experts%20at%20the%20Faculty%20of%20Social%20Sciences_2021.pdf - 2026-05-07

Assessment and simulation of global terrestrial latent heat flux by synthesis of CMIP5 climate models and surface eddy covariance observations

The latent heat flux (LE) between the terrestrial biosphere and atmosphere is a major driver of the global hydrological cycle. In this study, we evaluated LE simulations by 45 general circulation models (GCMs) in the Coupled Model Intercomparison Project Phase 5 (CMIP5) by a comparison with eddy covariance (EC) observations from 240 globally distributed sites from 2000 to 2009. In addition, we imp

Biomarkers In Prediction of Acute Mesenteric Ischaemia : a prospective multicentre study (BIPAMI study): a study protocol

Background: Acute mesenteric ischaemia (AMI) is a life-threatening disease where early diagnosis is critical to avoid morbidity and mortality from extensive irreversible bowel necrosis. Appropriate prediction of presence of bowel necrosis is currently not available but would help to choose the optimal method of treatment. The study aims to identify combinations of biomarkers that can reliably iden

A9

Microsoft Word - Zambia macro final.doc MACRO STUDY By Institute of Economic and Social Research University of Zambia _______________________________ Collaborative Study between Lund University & The Institute of Economic and Social Research, University of Zambia On the Project African Food Crisis – The relevance of Asian models July 2003 ©Oliver Saasa (2003), Agricultural I

https://www.keg.lu.se/en/sites/keg.lu.se.en/files/a9.pdf - 2026-05-07

General Meeting Co-location 250327 0

General meeting co-location General meeting co-location MGeo 27 MARS 2025 RECORDING • The meeting will be recorded and made available on Teams • Time for questions will therefore be at the end of the presentation • Questions will not be recorded Today's agenda • Introduction of Akademiska hus’ organisation • Introduction of Paras Bygg, contractor • General information from Paras Bygg • What has ha

https://www.naturvetenskap.lu.se/internt/sites/naturvetenskap.lu.se.internt/files/2025-03/General%20meeting%20co-location%20250327_0.pdf - 2026-05-07

Literature lists

EMP IMEP15 - ESA Environmental Systems and the Anthropocene Mandatory readingMandatory readingTextbookEnvironment, 10th EditionAuthors: David M. Hassenzahl; Mary Catherine Hager; Nancy Y. Gift; Linda R. Berg; Peter H. RavenChapter 1: Introducing Environmental Science and SustainabilityChapter 3: Ecosystems and EnergyChapter 4: Ecosystems and the Physical EnvironmentChapter 5: Ecosystems and Living

https://www.iiiee.lu.se/masters-programme-environmental-management-and-policy-emp/literature-lists - 2026-05-05