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Parkinson: On course against Cure. Our research group focuses on Parkinson's disease (PD), the second most common neurodegenerative disease, with approximately 20 000 patients in Sweden and 2.3 million in Europe.

Vid kronisk myeloisk leukemi har målstyrd, kontinuerlig behandling med tyrosinkinashämmare lett till dramatiskt förbättrad överlevnad. Efter ett flertal år uppnås djupt molekylärt svar hos ca 50 procent av patienterna; ca 50 procent av dem kan då avbryta behandlingen utan tecken på återfall. Kontinuerlig behandling med tyrosinkinashämmare kan ge långsiktiga biverkningar. Efter patentutgång för imaChronic myeloid leukemia - a model disease for targeted therapy Chronic myeloid leukemia (CML) pioneered as the first human malignancy linked to a specific cytogenetic aberration (the Philadelphia chromosome), which led the way to specific targeted therapies with imatinib (Glivec) and later tyrosine kinase inhibitors (TKI). Continuous TKI administration, blocking the oncogenic fusion protein Bcr-A

Diabetes results from loss or dysfunction of insulin producing beta cells in the pancreas. Despite insulin injection treatment, diabetic patients suffer from long-term complications, such as blindness and kidney failure. Therefore, a central goal of diabetes research is to regenerate beta cells or produce large numbers of functional beta cells for transplantation. The successful generation of beta

Abstract in Undetermined Este trabajo presenta el desarrollo de un banco de pruebas experimental para el análisis de la respuesta mecánica de los asientos de vehículos durante la entrada y salida de pasajeros. Para realizar este desarrollo, se consideran dos fases: la primera fase es la captura de datos, realizada mediante una manta sensorizada con una red de galgas de presión y un sistema de foto

Virus är bland de enklaste biologiska objekt i vår omgivning. Vanligen består de av en behållare av protein molekyler, en så kallad viruskapsel, som att bygga på denna viktiga insikt leder vi en bred studie av Herpesvirus där vi utforskar fysikaliska mekanismer som styr virus infektionen och ge en möjlighet till att kontrollera och även stoppa den. Dessutom öppnar studierna porten till strategierMy research area is Virus Biophysics. Research focuses on key physical mechanisms controlling replication of double-stranded DNA and RNA viruses. Experimental model systems used in my group are dsDNA bacteriophages, human Herpes viruses and Rotaviruses. I am specifically interested in physical mechanisms of genome packaging and ejection from viral capsids, viral packaging motors, DNA structural tr

Preeclampsia is a severe pregnancy-related condition that annually affects 10M women worldwide. The etiology is largely unknown and diagnosis is currently based on maternal clinical symptoms: high blood pressure and organ damage manifesting after 20 weeks of gestation. Delivery is currently the only cure. Increased long-term risk for cardiovascular diseases and stroke after preeclampsia point to i

Omegapoint AB acquired a TurtleBot 2 to explore one of the more popular open source robots on the market. Omegapoint wanted a web application, written specifically for them, to control the TurtleBot 2 for use in the Omegapoint office environment. One of the main things taken into consideration when designing the application was that it had to be runnable and usable not only on stationary computers

There are currently increasing concerns about escalating crude oil prices, depleted petroleum resources, and environmental damages caused by plastics. In light of this, bio-based and biodegradable materials, such as polyhydroxyalkanoates (PHAs), have gained global attention from industry and academia as sustainable alternatives to petroleum-based materials. Poly-hydroxybutyrate (PHB) is the simple