Filetype
Stability is a fundamental property affecting function, activity, and regulation of biomolecules. Stability changes are often found for mutated proteins involved in diseases. Stability predictors computationally predict protein-stability changes caused by mutations. We performed a systematic analysis of 11 online stability predictors' performances. These predictors are CUPSAT, Dmutant, FoldX, I-Mu
Antigenic diversity in pathogenic microbes can be a result of at least three different processes: diversifying selection by acquired immunity, host–pathogen coevolution and/or host specialization. Here, we investigate whether host specialization drives diversity at ospC (which encodes an immunodominant surface protein) in the tick-transmitted bacterium Borrelia afzelii. We determined prevalence an
While the so-called “end of public space” literature, focusing on encroachment of private interests and state surveillance, has contributed to critical thinking of access (or the lack thereof) to public space, and the loss of publicity of public space, the conceptual tools such literature offers to understand contestations in and over public space have remained underdeveloped or, at best, underexp
The interaction of blood coagulation factor X and its Gla-containing fragments with negatively charged phospholipid membranes composed of 25 mol% phosphatidylserine (PtdSer) and 75 mol% phosphatidylcholine (PtdCho) was studied by surface plasmon resonance. The binding to 100 mol% PtdCho membranes was negligible. The calcium dependence in the membrane binding was evaluated for intact bovine factor
The effects of data uncertainty in applications of the critical loads concept were investigated on different spatial resolutions in Sweden and northern Czech Republic. Critical loads of acidity (CL) were calculated for Sweden using the biogeochemical model PROFILE. Three methods with different structural complexity were used to estimate the adverse effects of SO2 concentrations in northern Czech R
Feedbacks mechanisms are essential components of our climate system, as they either increase or decrease changes in climate-related quantities in the presence of external forcings. In this work, we provide the first quantitative estimate regarding the terrestrial climate feedback loop connecting the increasing atmospheric carbon dioxide concentration, changes in gross primary production (GPP) asso
Accident prediction models are often used to predict the number of accidents on segments and at intersections in the road network. Most often the models are developed for a total number of crashes for the facility, or crashes by severity. However, the frequency and severity of crashes of different types can be expected to vary with regards to the underlying phenomena that cause them to occur. To b
Popular Abstract in Swedish Vad är det för något i human mjölk som dödar cancer celler? Kan “fel” veckade proteiner vara nyttiga? Kan fett vara inblandat i protein veckning? Det är några av frågorna som tas upp i denna avhandling. Allt levande består av proteiner som i sin tur är uppbyggda av amino syror. Det finns 20 st. olika amino syror som på olika sätt kan länkas samman till proteinkedjor. DBy varying its secondary or tertiary structure a single protein can attain new biological functions. The amyloid forming proteins are the best known examples where a change in conformation leads to the formation of amyloid fibrils that accumulate in tissues and cause disease. a-lactalbumin in contrast, is an example of a protein that acquires a beneficial function when the conformation is altered
Accident prediction models are often used to predict the number of accidents on segments and at intersections in the road network. Most often the models are developed for a total number of crashes for the facility, or crashes by severity. However, the frequency and severity of crashes of different types can be expected to vary with regards to the underlying phenomena that cause them to occur. To b
This thesis demonstrates the usefulness of sedimentary pigments as biomarkers of environmental change in estuarine systems and as biomarkers in lakes in relation to climate change. These are two fields where sediment pigment records as measured by high-performance liquid chromatography (HPLC) are emerging areas of study. A detailed study was undertaken to examine the effects of different storage o
1 Utbildningsplan 1. IDENTIFIKATION • Programmets namn och inriktning: musikerutbildning, arrangering klassisk inriktning. • Omfattning i högskolepoäng: 180. • Nivå: G. • Programkod: KGMUS. Inriktning: ARKL. • Utbildningsplanen är beslutad i Konstnärliga fakultetsstyrelsen den 11 augusti 2008. Utbild ningsplanen träder i kraft den 11 augusti 2008. 2. PROGRAMBESKRIVNING Musikerutbildning, arranger
https://www.mhm.lu.se/sites/mhm.lu.se/files/kgmus_arkl_sve.pdf - 2026-05-11
– 436 – Utbildningsplan 1 Identifikation • Programmets namn och inriktning: musikerutbildning, interpretation diplom. • Omfattning i högskolepoäng: 120. • Nivå: A. • Programkod: KAMID. • Utbildningsplanen är beslutad i Konstnärliga fakultetsstyrelsen den 14 februari 2007. Utbild ningsplanen träder i kraft den 1 juli 2007. 2 Programbeskrivning Musikerutbildning, solistisk interpretation, syftar ti
https://www.mhm.lu.se/sites/mhm.lu.se/files/musikerutbildning_interpretation_diplom.pdf - 2026-05-11
– 180 – Utbildningsplan 1 Identifikation • Programmets namn och inriktning: musikerutbildning, arrangering/komposition klassisk inriktning. • Omfattning i högskolepoäng: 180. • Nivå: G. • Programkod: KGMUS. Inriktning: ARKL. • Utbildningsplanen är beslutad i Konstnärliga fakultetsstyrelsen den 23 oktober 2013. Utbild ningsplanen träder i kraft den 2 september 2014. 2 Programbeskrivning Musikerutb
https://www.mhm.lu.se/sites/mhm.lu.se/files/utbildnings_utbplan_kandidat_arrklass.pdf - 2026-05-11
– 158 – Utbildningsplan 1 Identifikation • Programmets namn och inriktning: musikerutbildning, komposition. • Omfattning i högskolepoäng: 180. • Nivå: G. • Programkod: KGMUS. Inriktning: KOMP. • Utbildningsplanen är beslutad i Konstnärliga fakultetsstyrelsen den 11 augusti 2008. Utbild ningsplanen träder i kraft den 11 augusti 2008. 2 Programbeskrivning Musikerutbildning, komposition, syftar till
https://www.mhm.lu.se/sites/mhm.lu.se/files/utbildnings_utbplan_kandidat_komp.pdf - 2026-05-11
Råd och anvisningar till doktoranden och institutionen i samband med disputation inom den naturvetenskapliga fakulteten Sida 1 av 13 Kansli N RÅD OCH ANVISNINGAR Datum 2025-11-13 Råd och anvisningar till doktoranden och institutionen i samband med disputation inom den naturvetenskapliga fakulteten 1 Avhandlingen Doktorsavhandlingen utformas antingen som ett enhetligt sammanhängande vetenskapligt v
https://www.naturvetenskap.lu.se/sites/naturvetenskap.lu.se/files/2025-11/Rad-och-anvisningar-disputation-251113.pdf - 2026-05-11
3D-modeller är grunden i det som kallas BIM och är något som används mer flitigt inom byggbranschen men desto mindre inom anläggningsprojekt. BIM har utvecklats mer och mer för att underlätta samordningen av flera aktörer och lösa konflikter i olika faser och skeden. Med ytterligare dimensioner integreras även tid och kostnadsaspekten på projektet som resulterar i ett mer produktivt byggande. Gru3D-models are the base of what is called BIM. It is used more and more within in the construction industry over all, but not as much in the field of infrastructure projects. BIM is developed to coordinate several actors and resolve conflicts in different phases of the construction. With dimensions integrated in the model, such as time and cost aspect, it result in a more productive project. The m
Current hemophilia B treatment guidelines recommend routine prophylaxis with factor IX (FIX) replacement products, tailored to maintain plasma activity at levels that will prevent bleeds. However, plasma FIX activity may not be the primary determinant or best indicator of hemostatic efficacy due to its extravascular distribution. FIX replacement therapy has evolved to include extended half-life (E
BACKGROUND: Hair cosmetics such as hair dyes, bleaching, waving, and cleansing products are composed of numerous chemical ingredients. Allergic reactions to these contact allergens, other than p-phenylenediamine, are rarely reported.OBJECTIVES: To study the incidence of patch test reactions to hair cosmetic allergens and identify the factors associated with hair cosmetic allergy in Thailand.METHOD
Antibiotic resistance is currently an extensive medical challenge worldwide, with global numbers increasing steadily. Recent data have highlighted wastewater treatment plants as a reservoir of resistance genes. The impact of these findings for human health can best be summarized using a One Health concept. However, the molecular mechanisms impacting resistance spread have not been carefully evalua
Reliable information on solar activity over the Holocene period is important to predict the Sun in the future and to understand the mechanism behind the Sun-climate linkage. Presently, there are discrepancies in the proxy data of solar activity due to reasons that are not yet understood. This leads to major uncertainties in Holocene solar reconstructions. This PhD project aims to improve the Holoc
