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Right before northern hemisphere’s summer shifts to autumn small insect-eatingbirds start lengthy journeys to tropical regions. It is well established that temporarylack food and annual changes in weather are the ultimate reasons for this behavior.On a proximal level however, the process is poorly understood. Yet crosscontinental bird migration is a widespread phenomenon that has evolved severalti
4-1BB (CD137) is an activation-induced costimulatory receptor that regulates immune responses of activated CD8 T and natural killer cells, by enhancing proliferation, survival, cytolytic activity, and IFNγ production. The ability to induce potent antitumor activity by stimulating 4-1BB on tumor-specific cytotoxic T cells makes 4-1BB an attractive target for designing novel immuno-oncology therapeu
The accurate estimation of soil carbon (C) pool and fluxes is a prerequisite to better understand the terrestrial C feedback to climate change. However, recent studies showed considerable uncertainties in soil C estimates. To provide a reliable C estimate in the grasslands of the Qinghai-Tibet Plateau (QTP), we calibrated key parameters in a process-based ecosystem model (the CENTURY model) throug
This PhD thesis examines how application of 3D visualization and related digital analytical tools is having a transformative impact on archaeological practice via improvement of visual-spatial thinking and the strengthening of conceptual understanding. However, the deployment of these new digital methods is essentially still at an experimental stage. Therefore, the thesis undertakes a critical eva
PURPOSETo assess interval cancer rate in a large, prospective digital breast tomosynthesis (DBT) screening trial in comparison with a concurrent screening population and to assess tumor characteristics of interval cancers in DBT-screening.METHOD AND MATERIALSThe prospective ****Trial, comparing digital breast tomosynthesis (DBT) with digital mammography (DM) in 14,848 women has shown a significant
Background: Atherosclerotic plaque ruptures, triggered by blood flow–associated biomechanical forces, cause most myocardial infarctions and strokes. Objectives: This study aims to investigate the exact location and underlying mechanisms of atherosclerotic plaque ruptures, identifying therapeutic targets against cardiovascular events. Methods: Histology, electron microscopy, bulk and spatial RNA se
Neurotensin (NT) is a small protein implicated in the regulation of energy balance which acts as both a neurotransmitter in the central nervous system and as a gastrointestinal peptide. In the gut, NT is secreted after fat ingestion and promotes the absorption of fatty acids. The circulating levels of its precursor, pro-NT, predicts the presence and development of metabolic and cardiovascular dise
An energy transition from centralised and fossil-fuelled installations towards decentralised and renewable energy has been advocated by governments, businesses and academia. In the EU it has become a regional strategy, and a desire of citizens, to enable communities to take an active role in the energy market in the hopes of transitioning to an increasingly local, renewable and participatory futur
The term Middle-income Trap (MIT) is relatively new, originating thirteen years ago, but has since generated significant debate. It is used by politicians to channel national reforms and has given rise to a vast amount of research about growth slowdowns in middle-income countries (MICs). The term describes the higher prevalence of economic growth slowdowns in MICs, which impedes their transition i
Glacier advances in the Écrins massif (French Alps) during the Late Glacial and the Early Holocene are poorly constrained. Based on field observations, a high-resolution digital elevation model and an orthophoto, glacial landforms in the upper Drac Blanc catchment were mapped. Thanks to 42 new 10Be exposure ages, the timing of the stabilisation of selected moraines was constrained. The application
Att dika skogar till förmån för bland annat bättre tillväxt kan påverka och förändra faktorer som marktemperatur och markfuktighet vilka är de viktigaste faktorerna för markrespirationen och flödet av koldioxid till atmosfären. Markrespirationen svarar för huvuddelen av koldioxidflödet till atmosfären från ett markbundet ekosystem. Koldioxid är en viktig växthusgas och små förändringar av flödet kDitching forests in favor of for example better tree growth can affect and change factors such as soil temperature and soil moisture. Those are the most important factors for soil respiration and the flow of carbon dioxide (CO2) into the atmosphere. The soil respiration accounts for the major flux of CO2 to the atmosphere from the terrestrial ecosystem. CO2 is an important greenhouse gas and small
The Greenland Ice sheet (GIS) is the second largest ice sheet on Earth and thus stores a large amount of Earths freshwater. Because of climate change and the Arctic amplification, GIS is experiencing changes and increased melt rates. The total mass budget determines the amount of sea level rise caused by input from freshwater from the GIS. Surface mass balance (SMB) plus the dynamic mass losses fr
Denna studie undersöker den politiska och allmänna diskurs som konstruerar identiteten landsbygdsbo i Sverige, samt vilka konsekvenser denna diskurs har gällande förväntningar på, och förväntningar hos boende i rurala regioner i Sverige. Studien fokuserar på stängningen av Sollefteå BB i Sollefteå sjukhus, Västernorrlands landsting (numera region), i januari 2017 och den ockupation av sjukhuset soThis study examines the political and popular discourse that constructs the identity of the rural citizen in Sweden, and what consequences this discourse has on expectations on, and expectations of rural citizens in Sweden. The study focuses on the closing of the birthing clinic in Sollefteå hospital, Västernorrland county, in January 2017 and the occupation of the ward that followed thereafter. E
When an agitator is in commission for an extended period of time the impellers can become clogged. In order to clean the impeller, the agitator is runned backwards. This is one of the main functions for a product that CG Drives & Automation is developing for a customer in the agitator business. The purpose of this bachelor thesis is to develop and test this product for CG Drives & Automati
Seagrass systems are integral components of both local and global carbon cycles and contribute to substantial modifications of seawater biogeochemistry which has ecological ramifications. However, the influence of the roots and rhizomes of seagrasses on surrounding porewater biogeochemistry is not fully understood, and it remains to be determined what exact role this marine plant and the associate
I uppsatsen du har framför dig undersöker jag målsägandens ansvar i förhål-lande till en tilltalads uppsåt eller oaktsamhet avseende målsägandens ofrivil-liga deltagande i en sexuell handling. Vi befinner oss alltså i de två första pa-ragraferna av brottsbalkens sjätte kapitel, 6:1 och 6:1 a BrB. Min undersök-ning kretsar dock inte framförallt kring gällande rätt utan kring hovrätternas tillämpninThis essay investigates whether the law or its practice can be said to impose on the plaintiff a responsibility in relation to the defendant’s intent or negli-gence regarding the plaintiff’s involuntary partaking in a sexual act with the defendant. We are hence located in the first two paragraphs of the sixth chap-ter in the Swedish criminal code, 6:1 and 6:1 a Brottsbalk (1962:700). My essay does
Animals monitor environmental ques by translating them into electrical signals through a depolarization of the electric potential over the cell membrane of nerve cells. A way to initiate the depolarization is through activation of receptors that are ion channels. These channels can facilitate the diffusion ions across membranes driven by the differences in concentration and electrical charge on ea
