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Insulin stimulates fusion, but not tethering, of GLUT4 vesicles in skeletal muscle of HA-GLUT4-GFP transgenic mice. Am J Physiol Endocrinol Metab 302: E950-E960, 2012. First published January 31, 2012; doi:10.1152/ajpendo.00466.2011.-Insulin regulates glucose uptake into fat and muscle by modulating the subcellular distribution of GLUT4 between the cell surface and intracellular compartments. Howe
Popular Abstract in English Every year globally, an estimated 1.7 million women are diagnosed with breast cancer, while over half a million are killed by this disease. The principal cause of death is metastasis, which is the spreading of the cancer cells from the breast to other vital organs like the brain, liver or lungs, resulting in organ failure and subsequently death. Even though the past decMetastasis is a complex process that remains a major challenge in the clinical management of cancer, because most cancer-related deaths are attributed to disseminated disease rather than the primary tumor. Despite the significant advances in the prediction of prognosis, and therapeutic management of primary breast cancers, coupled with the substantial improvement in our understanding of the molecu
In this study, field experiments and numerical simulations for different drip irrigation treatments in a sandy loam soil were conducted to investigate soil water and salinity distribution as well as dye infiltration patterns. Three treatments, surface drip irrigation without and with plastic mulch (T1 and T2, respectively); and subsurface drip irrigation (T3), were used. In addition, daily and bi-
Background: Covered biliary metal stents have been developed to prevent tumor ingrowth. Previous comparative studies are limited and often include few patients. Objective: To compare differences in stent patency, patient survival, and complication rates between covered and uncovered nitinol stents in patients with malignant biliary obstruction. Design: Randomized, multicenter trial conducted betwe
Streptococcus pyogenes is an important human pathogen and surface structures allow it to adhere to, colonize and invade the human host. Proteins containing leucine rich repeats (LRR) have been indentified in mammals, viruses, archaea and several bacterial species. The LRRs are often involved in protein-protein interaction, are typically 20-30 amino acids long and the defining feature of the LRR mo
The kinin system is activated when high-molecular-weight kininogen (HK) is cleaved by plasma kallikrein thus generating bradykinin. Bradykinin is a potent proinflammatory peptide that induces plasma leakage, blood pressure drop, liberation of inflammatory cytokines and pain. Vasculitis is an autoimmune systemic inflammatory disease, characterized by leukocyte inflammation in and around vessel wall
In the study reported here we examined the short-term effects (1-3 years) of slash retention (SR) and the long-term effects (13-15 years) of wood-ash application (A) on fine roots and mycorrhizae in a 40-year-old Norway spruce forest in southwest Sweden. Soil cores were used to obtain estimates of the biomass (g m(-2)) of roots in three diameter classes (< 0.5, 0.5-1 and 1-2 mm), root length densi
Epigenetics may play a role in the pathophysiology of type 2 diabetes (T2D), and increased DNA methylation of the metabolic master regulator peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PPARGC1A) has been reported in muscle and pancreatic islets from T2D patients and in muscle from individuals at risk of T2D. This study aimed to investigate DNA promoter methylation and gen
Lunds universitet 1 Action plan for gender equality and equal opportunities for the Department of Physical Geography and Ecosystem Science, October 2015 – December 2016, approved at the board meeting 8 October 2015 Discrimination Act (2008:567) The purpose of the Act Chapter 1, Section 1 The purpose of this Act is to combat discrimination and in other ways promote equal rights and opportunities re
https://www.nateko.lu.se/sites/nateko.lu.se/files/jamstalldhetsplan_ines_engelsk_version.pdf - 2026-07-18
boardmeeting130514final 1 SASNET Swedish South Asian Studies Network Board Meeting, May 14, 2013, 13.30-17.00 Venue: Conference room, 1st floor, Centre for East and South-East Asian Studies, House Alfa 1, Scheelevägen 15D, Ideon Research Park, Lund Board Members present: Anna Lindberg, Fredrik Tufvesson, Helle Rydström, Anders Fänge, Olle Qvarnström, Hawwa Lubna, and Stefan Jonsson. Staff represen
https://www.sasnet.lu.se/sites/sasnet.lu.se/files/board1301.pdf - 2026-07-18
Uppdrag till Expertgruppen ang BIM/Geodata Lars Harrie Department of Physical Geography and Ecosystem Science, Lund University Some activities in Geographic Information Science at INES Geographic Information Science at INES Data integration/generalisation Spatial data infrastructure Demography/Epidemiology Tourism City modelling Hydrological modelling Remote sensing- GIS ICOS CP - Geomatics Dispos
https://www.nateko.lu.se/sv/sites/nateko.lu.se.sv/files/ines_2019-09.pdf - 2026-07-18
The occurrence of an early Preboreal climatic cooling/oscillation (PBO) in lacustrine and glacial records from northwest Europe, Iceland and Greenland is reviewed and documented. The often subtle response of the proxy records to this oscillation, in combination with its short duration, make it difficult to detect. Owing to its chronostratigraphic position between the 10000-9900 and 9600-9500 14C p
With the increasing Internet usage and the increase of W-commerce in Sweden, online marketing has become an essential and crucial activity for most industries and companies. Online marketing has developed rapidly and there are today a big number of digital channels and tools to add into the marketing strategy in order to meet the changing consumer behaviour. Today we are starting to see a number o
En sedimenttransekt bestående av tio punkter borrades med hjälp av en ryssborr i alkärret vid Kalvöviken på Biskopsmålahalvön i centrala Blekinge. I huvudpunkten togs tre parallella 1 m långa borrkärnor. Sedimentprov togs ur borrkärnorna och undersöktes med hjälp av glödförlust, mineralmagnetiska-, makrofossil-, pollen- och strukturanalyser. Kronologin fastställdes genom två kol-14-dateringar kompA sediment transect based on ten corings were performed with a Russian peat corer in the aldercarr at Kalvöviken on the Biskopsmåla Peninsula in central Blekinge. Three parallel sediment cores were collected at the master coring point. These cores were subsampled and studied by means of loss of ignition (LOI), mineral magnetic measurements, macrofossil analysis, pollen analysis and structural anal
Tre borrkärnor bestående av sjösediment, vardera 1.5 meter långa, från Byestadsjön i Småland, Sverige studerades med hjälp av mineralmagnetiska- kol- pollen- och röntgenflourosens (XRF)- analyser. Målet med studien var att rekonstruera tidig Holocen miljö, med fokus på tiden mellan 9000-7000 år sedan och därmed avgöra om det kalla klimatåterslaget cirka 8200 före nutid påverkade regionen eller ej.Three sediment cores, each 1.5 meters in length, obtained from Lake Byestadsjön in the province of Småland, southern Sweden were studied with high resolution mineral magnetic measurements, carbon content, pollen analysis and XRF analysis. The aim was to reconstruct the early Holocene environment, with focus on the period between 9000-7000 cal yr BP, and thereby conclude if the 8200 cal yr BP cooli
A personal transporter is under development at LTH, Industrial Electrical Engineering and Automation, IEA. A wireless link is desired to develop control remotely for the transporter. The development of the control becomes easier without wires and if the transporter can move freely within the range of the link. A link is built, using Bluetooth devices and a microprocessor from Microchip. This link
The major histocompatibility complex (MHC) is a membrane protein group of central importance in the immune system. It is divided into two main classes, class I and class II. The MHCs are highly polymorphic which is believed to be indication of trans-species polymorphism (TSP). There is TSP when an allele is maintained in two species through a speciation event. The songbirds that I study here belon
This report deals with lime modification of clay till. Lime modification means that the compaction properties of the soil are improved by the addition of lime. The report consists of three main parts: 1) Description of the geotechnical properties of clay till and how lime modification affects the properties; 2) Description of the implementation of lime modification and the tests conducted at a con
Although most microplastics (<5 mm in length or diameter, depending on shape) are not visible they can be found everywhere in the environment. The effects can be devastating and much greater than what has been proven so far, as there is a lack of knowledge about the impact, spread and extent of microplastics. The Swedish EPA published a report in June 2017 which reveals a number of major microplas
