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The prevalence of allergic disease is continuing to increase worldwide, and it has even become a major concern in public health. Allergic reactions are developed to otherwise harmless substances and may be both life-threatening as well as discomforting for patients in their daily life. Therefore, a more detailed knowledge about how antibodies interact with allergens and effector cells in allergic
While the eddy covariance (EC) technique is a well-established method for measuring water fluxes (i.e., evaporation or 'evapotranspiration’, ET), the measurement is susceptible to many uncertainties. One such issue is the potential underestimation of ET when relative humidity (RH) is high (>70%), due to low-pass filtering with some EC systems. Yet, this underestimation for different types of EC sy
CURRENT DYNAMICS IN SOUTHEAST ASIA NEW PERSPECTIVES IN POLITICAL ECONOMY AND COMPARATIVE POLITICS SEMINAIRE EUROPÉEN / BIMESTRIEL Vendredi / 14h-18h Lieux : Inalco, Maison de la recherche, 2 rue de Lille, Paris 7e ; ou CERI, Paris 7e. COORDINATION Elsa Lafaye de Micheaux, CASE, Inalco; Astrid Norén-Nilsson, ACE, Lund; David Camroux, CERI, Sciences Po; Delphine Allès, CASE, Inalco. COMITÉ SCIENTIFI
https://www.ace.lu.se/sites/ace.lu.se/files/2024-08/Current%20Dynamics%20Programme%202024-2025%20V3.pdf - 2026-07-16
CURRENT DYNAMICS IN SOUTHEAST ASIA NEW PERSPECTIVES IN POLITICAL ECONOMY AND COMPARATIVE POLITICS SEMINAIRE EUROPÉEN / BIMESTRIEL Vendredi / 14h-18h Lieux Inalco, Maison de la recherche, 2 rue de Lille, Paris 7e ; ACE, Sölvegatan 18, Lund ou CERI, 28 rue des Saints Pères, Paris 7e. COORDINATION Elsa Lafaye de Micheaux, CASE, Inalco ; Astrid Norén-Nilsson, ACE, Lund; David Camroux, CERI, Sciences P
https://www.ace.lu.se/sites/ace.lu.se/files/2024-10/Current%20Dynamics%20in%20Southeast%20Asia_2024-2025.pdf - 2026-07-16
Abstract in French Cette etude reprend les resultats d'une recherche co-financee par la Communaute Europeenne sur les effets thermiques des vetements de protection et sur l'astreinte physiologique qui en resulte dans les conditions de travail. L'etude concerne l'infiuence de l'asymetrie de rayonnement thermique. L'echange thermique a ete mesure al'aide d'un mannequin calorimetrique sous l'influencThis report considers results of an ED funded research on thermal properties ofprotective clothing and their use in the assessment of the thermal strain at work. In order to study the effects of the asymmetry oflong wave thermal radiation on the heat transfer through protective clothing, the heat loss under all-side and unilaterally applied radiation with the same incident radiant power of 279 W/m
Objective. Antileukoproteinase (ALP) is a physiologic inhibitor of granulocytic serine proteases. The present study was undertaken to investigate its therapeutic benefit in an antibody-transfer model of erosive polyarthritis and to elucidate its potential to interfere with immune complex-dependent inflammatory pathways. Methods. Arthritis development was induced in male (BALB/c x B10.Q)F-1 mice by
Transplantation of allogeneic embryonic neural tissue is a potential treatment for patients with Parkinson's and Huntington's diseases. The supply of human donor tissue is limited, and alternatives such as the use of animal (e.g., porcine) donor tissue are currently being evaluated. Before porcine grafts can be used clinically, strategies to prevent neural xenograft rejection must be developed. Kn
Complement C2 deficiency (C2D) is associated with immunological diseases and increased susceptibility to invasive infections caused by encapsulated bacteria such as Neisseria menigitidis. In this study we evaluate the immunogenicity of vaccination against N. menigitidis in C2D. C2D patients (n=22) and controls (n=52) were given a tetravalent meningococcal polysaccharide vaccine. Serum bactericidal
Introduction: Recent haemophilia treatment advances include new recombinant FVIII (rFVIII) products with improved pharmacokinetic (PK) properties that aim to reduce the burden of prophylaxis. These treatments are commonly referred to as extended half-life rFVIII products (EHL rFVIII). There is no uniform definition of what constitutes an EHL rFVIII. Such a definition would help physicians, patient
Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Recently we reported that EDC34, a C-terminal peptide derived from TFPI-2, exerts a broad antimicrobial activity. In the present study, we describe a previously unknown antimicrobial mode of ac
Small synthetic ligands for protein purification have become increasingly interesting with the growing need for cheap chromatographic materials for protein purification and especially for the purification of monoclonal antibodies (mAbs). Today, Protein A-based chromatographic resins are the most commonly used capture step in mAb down stream processing; however, the use of Protein A chromatography
Hu11B6 is a monoclonal antibody that internalizes in cells expressing androgen receptor (AR)-regulated prostate-specific enzyme human kallikrein-related peptidase 2 (hK2; KLK2). In multiple rodent models, Actinium-225-labeled hu11B6-IgG1 ([225Ac]hu11B6-IgG1) has shown promising treatment efficacy. In the present study, we investigated options to enhance and optimize [225Ac]hu11B6 treatment. First,
Antimicrobial peptides (AMPs) are evolutionarily ancient molecules. They are essential innate immune response molecules that protect organisms from invading pathogens. Tissue factor pathway inhibitors (TFPI-1 and TFPI-2) C-terminal derived peptides exert host defense mechanisms against microbes. Studies showed that in human plasma, C-terminal TFPI-1 and -2 derived peptides mediate bacterial killin
