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Streptococcus pyogenes secreted enzymes interacting with the human host

Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that

Structural determination of Streptococcus pyogenes M1 protein interactions with human immunoglobulin G using integrative structural biology

Streptococcus pyogenes (Group A streptococcus; GAS) is an important human pathogen responsible for mild to severe, life-threatening infections. GAS expresses a wide range of virulence factors, including the M family proteins. The M proteins allow the bacteria to evade parts of the human immune defenses by triggering the formation of a dense coat of plasma proteins surrounding the bacteria, includi

Balancing effluent quality, greenhouse gas emissions and operational cost - developing dynamical models for intergrated benchmarking of wastewater treatment plants

The scope for wastewater treatment plants (WWTPs) widens to consider not only water quality and cost, but also energy efficiency and greenhouse gas (GHG) emissions. The on-going research project, “Development and dynamic analysis of operational strategies for enhanced energy efficiency of wastewater treatment systems” aims to develop a tool for integrated evaluation of energy efficiency and greenh

Results of a phase I/II study of ocrelizumab, a fully humanized anti-CD20 mAb, in patients with relapsed/refractory follicular lymphoma

Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3

Cost Reduction of Drive Unit

The purpose of this project was to reduce the production cost of the drive unit from AB Ph. Nederman & Co product Flowline with 50 % to make it more competitive, and the result is this report as well as a fully operational prototype. During the process I have looked into all of the functions of the existing product and have tried to improve them. The function which I have put most time and eff

Trading and Trading Costs : A study of the OMX30 during 2001-2006

OMX spreads decline from 2001-2006. The average volume and average number of trades / trading frequency increases over this period, whereas the average trade size decreases consistent with greater retail investor activity. Macroeconomic factors such as interest rates, inflation rate and GDP rate do not seem to affect changes in the spreads.

Potentialities of manganese ore and iron-carbon particles for pharmaceuticals and personal care products removal in electroactive constructed wetland

This study explores the use of manganese ore, iron-carbon particles (Fe-C), and gravel as anode fillers in electroactive constructed wetlands (ECWs) to treat wastewater containing pharmaceuticals and personal care products (PPCPs) including ciprofloxacin (CIP), ofloxacin (OFL), and naproxen (NPX), while also assessing bioelectricity production. Although the presence of PPCPs reduced pollutant remo

From Genotypes of Immunoglobulin Constant Heavy G Chains (Fcγ) (GM) Genes (IGHG) to Phenotypes in Childhood Asthma.

Background: IgE-mediated allergy is associated with immunoglobulin heavy constant G chain (Fcγ) (GM) genes (IGHG) on chromosome 14q32.3. Investigation of the alternative GM allotypes of γ3, γ1 and γ2 chains has disclosed new structural and functional IgG subclasses and B-cell variants, with possible effects on childhood asthma. Objective: To investigate different IGHG (GM) gene complexes in a

Evaluating Off-the-shelf Hardware for Indoor Positioning

An indoor positioning system (IPS) is a system to locate objects in indoor environments using radio waves, magnetic fields, acoustic, optical and video signals or other sensory information with help of a number of known reference positions. Nowadays, indoor positioning based services are used in a wide variety of areas and indoor positioning is getting considerable attention from both research and

The Clean Development Mechanism in China- A Win-win Synergy?

Outstanding economic growth in China has its price to pay. By prioritizing economic growth as number-one issue, complementing cheap energy consumption has undeniably been side-by-side. Although the energy base on fossil-fuel energy consumption, together with inefficient technology has pushed forward China to lifting millions of the population out of poverty, it has also mounted emissions in China,

More-than-human borderlands of disease

Fencing ‘Risky’ Mobilities in the Eastern German Borderlands with Poland Tisdag 9 maj kl. 14.30-15.30 Larissa Fleischmann från Martin Luther University Halle-Wittenberg höll en presentation, som följdes av diskussion med Tracie Wilson från Ludwig-Maximilians-Universität, och frågor från deltagare. Seminariet hölls på Zoom.  Larissa Fleischmann is a researcher in human geography, whose work centers

https://www.cors.lu.se/formular/more-human-borderlands-disease - 2026-04-27

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R ED . JO H A N N A B ER G Q V IST R Y D ÉN O C H M A R IA LA R SSO N O m sam verkan, m ångfald och m ellanm änskliga m öten 9 78 91 88 47 39 74 Avdelningen för högskolepedagogisk utveckling Institutionen för utbildningsvetenskap Lunds Universitet. ISBN 978-91-88473-97-4 Om samverkan, mångfald och mellanmänskliga möten Proceedings från Lunds Universitets Pedagogiska Utvecklingskonferens 2017 RED.

https://www.ahu.lu.se/fileadmin/user_upload/ahu/PDF/Proceedings_fra__n_Lunds_Universitets_Pedagogiska_Utvecklingskonferens_2017.pdf - 2026-04-27