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OBJECTIVE: To investigate the possible role of FCGR2A 519A>G and FCGR3A 559A>C functional polymorphisms in the genetic predisposition to susceptibility to systemic sclerosis (SSc) or clinical phenotype. METHODS: A total of 1566 patients with SSc and 2271 geographically matched controls were included in our study. We analyzed the genotype and allele frequencies of the FCGR2A 519A>G and FCGR3A 559A>
Purpose: The purpose of this study is to investigate whether ESG ratings have any impact on cost of debt in European industrial companies. Furthermore, the study intends to contribute with empirical material to provide a clearer insight into the relationship between ESG and cost of debt for companies in carbon dioxide-intensive industries. Method: The study adopts a deductive approach with a quan
This thesis investigates how students navigate interpersonal and professional relationships in the context of neoliberal rationality and Web 2.0 digital infrastructures. Focusing on self-marketization practices and the conflict between online personas and real identities, the study draws on qualitative data from interviews and focus groups with university students aged 20–35. Using a dual theoreti
This paper explores a new method for evaluating the cost of verifying a contract. We relate these costs to the number of computations an algorithm needs to check that a contract satisfies certain criteria. Two different criteria that facilitate enforcement of the contract are studied. Our findings indicate bounds on the computational costs as the size of the contract grows. If each computation cos
Question: Considering ecological factors and life history, how easy is it for sexual reproduction (as a strategy) to invade and persist in a population where all individuals are reproducing asexually? Mathematical method: We use a population growth equation that despite its simplicity captures several relevant ecological parameters: age-specific survival, differential birth rates, as well as both
The epidemic of type 2 diabetes mellitus (T2DM) on a global scale is a matter of concern, not only from a public health perspective, but also with consideration of societal costs. The increased call on health care resources to treat and monitor T2DM and its complications could put a heavy burden on national health care systems and financing. An important contributing factor for development of T2DM
We consider general prepare-and-measure scenarios in which Alice can transmit qubit states to Bob, who can perform general measurements in the form of positive operator-valued measures (POVMs). We show that the statistics obtained in any such quantum protocol can be simulated by the purely classical means of shared randomness and two bits of communication. Furthermore, we prove that two bits of co
This case explores the rise and challenges of Vässla, a Swedish electric micromobility startup that positioned itself as a premium, sustainable alternative to gas-powered scooters. Despite strong brand differentiation, consumer demand, and initial success, Vässla faced operational difficulties and financial instability. Set in 2019, this case challenges students to assess whether Vässla’s brand st
Although the communication aspects of sport and football organizations are receiving in-creased scholarly attention, research from the perspective of fans of such organizations has mostly been neglected. This study problematizes the gap that exists be-tween the current social media communication of football organizations, that tend to be guided by commercial interests, and the expectation of fans
During the last two decades, corporate ESG practices have garnered significant attention from the global community. The development of responsible business practices in association with sustainability and the integration of stakeholders has become an important topic for firms reputation, their debt financing cost and long-term success. Drawing upon the stakeholder theory, where a firm's succes
Platelets express Toll-like receptor 4 (TLR4), and this has been shown to be responsible for the thrombocytopenia induced by lipopolysaccharide (LPS) administration in vivo. We studied the role of LPS in mediating platelet phagocytosis by THP-1 cells in vitro by flow cytometry. Opsonization of platelets with an IgG monoclonal (W6/32) antibody or with IgG autoantibody-positive sera from patients wi
OBJECTIVE: To determine costs of illness for adult diabetes mellitus (DM), including complications caused by DM. DESIGN: A population-based multicentre cross- sectional study including an interview and a physical examination of patients identified as having DM. The patients' medical records were analysed regarding diagnoses and complications attributable to DM. SETTING: Eight health care centres o
