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Single-strand RNA-binding proteins (RBPs) are involved in many aspects of RNA metabolism and in the regulation of gene transcription. The RBP RBM3 was recently suggested to be a proto-oncogene in colorectal cancer; however, such a role has not been corroborated by previous studies in the colon or other tumor types, and the prognostic implications of tumor-specific RBM3 expression remain unclear. M
In atrial fibrillation (AF), the ECG P-wave, which represents atrial depolarization, is replaced with chaotic and irregular fibrillation waves (f waves). The f-wave frequency, F f, shows significant variations over time. Cardiorespiratory interactions regulated by the autonomic nervous system have been suggested to play a role in such variations. We conducted a simulation study to test whether
My research centres on a topic that will be familiar to many of you – namely the proliferation of paperwork and documentation demands that characterises work in many contemporary organisations. More specifically, I take as my point of departure a crux from the Swedish education sector, namely that there is a broad will – from actors at all levels of the schooling system – politicians, the Swedish
Epigenetic mechanisms may contribute to idiopathic scoliosis (IS). We identified 8 monozygotic twin pairs with IS, 6 discordant (Cobb angle difference >10°) and 2 concordant (Cobb angle difference ≤2°). Genome‐wide methylation in blood was measured with the Infinium HumanMethylation EPIC Beadchip. We tested for differences in methylation and methylation variability between discordant twins and tes
Individuals with a family history of colorectal cancer (CRC) are at a high risk of developing CRC. Preclinical and population-based evidence suggests that selective serotonin reuptake inhibitors (SSRIs) might play a role in preventing CRC. We performed a nationwide cohort study to explore whether the use of SSRIs could reduce CRC risk among individuals with family history. We identified individual
The serum concentration of YKL-40, a matrix protein of specific granules in neutrophils, was determined by RIA in 90 patients hospitalized with pneumonia of suspected bacterial origin. Of these, 64 were followed prospectively during antibiotic treatment with blood samples taken on day 0 (on admission and the start of treatment) and on days 1, 3, 5, 7, 10, and 21. Serum YKL-40 at admission was incr
We suggest that a renewed focus on integration (broadly conceived) would enablethe field to contemplate the ways in which crisis dynamics interconnect with and amplify three founding and (and unresolved) dilemmas of the European project. These can be summarized as (a) the constant tension between the goal of delivering an EU-wide market order versus the desire to ensure social solidarity, (b) the
Popular Abstract in Swedish Movimiento al Socialismo (MAS) bildade regering i Bolivia 2006 med Evo Morales på presidentposten, framburna av folkliga protester mot tidigare, nyliberala regimer. Morales beskrivs ofta som landets första president med bakgrund i ursprungsbefolkningen. Hans regering utlovade en radikal omställning av den nationella politiken och tillkännagav att Bolivia nu är en "pluriEvo Morales and the Movimiento al Socialismo (MAS) took office in Bolivia in 2006, riding on the wave of fierce popular protests against previous, neoliberal regimes. Morales was depicted as the country’s first indigenous president. His government promised a radical transformation of national politics and rebranded Bolivia as a “plurinational state”. Under MAS, indigenous subjectivity has moved fr
Dysregulation of Wnt/beta-catenin signaling is a hallmark of colon cancer. Glycogen synthase kinase-3 beta (GSK-3 beta) can be a positive regulator of survival and proliferation of cultured colon cancer cell but its role in clinical colon cancer is unknown. Our objectives were to evaluate the role of GSK-3 beta in colon cancer. A tumor tissue microarray of primary colon cancers and metastases was
Previously, a single nucleotide polymorphism (SNP), rs9939609, in the FTO gene showed a much stronger association with all-cause mortality than expected from its association with body mass index (BMI), body fat mass index (FMI) and waist circumference (WC). This finding implies that the SNP has strong pleiotropic effects on adiposity and adiposity-independent pathological pathways that leads to in
The biosynthesis of chlorophyll has been demonstrated to require an extensive set of enzymes, the initial stages of which are shared with the synthesis of heme. Of these enzymes, the most enigmatic is the Mg-protoporphyrin IX monomethyl ester cyclase (EC 1.14.13.81). This enzyme requires components found associated with the plastid membrane and the plastid soluble fraction. One of the components,
This article argues for the importance of explicit discussions of what is valuable as a foundation for any disaster risk reduction initiative to be effective. It does so by stating that it is impossible to talk about risk at all if not having some notion of uncertain potential impacts on something that humans value. What is assumed as valuable and important to protect is then determining what haza
Risk för blodpropp vid autoimmuna sjukdomar – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Risk för blodpropp vid autoimmuna sjukdomar 2011-11-28 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Foto: Colourbox I en nationsövergripande
https://www.vetenskaphalsa.se/risk-for-blodpropp-vid-autoimmuna-sjukdomar/ - 2026-10-09
Olf-1/early B-cell factor (O/E-1) is a transcription factor important for B-lymphocyte and neuronal gene regulation. Here we report that all three known O/E genes (O/E-1, -2, and -3) are expressed in mouse adipose tissue and are upregulated during adipocyte differentiation. Forced expression of O/E-1 in either the preadipocyte cell line 3T3-L1 or mouse embryonic fibroblasts augmented adipogenesis,
A SNP upstream of the INSIG2 gene, rs7566605, was recently found to be associated with obesity as measured by body mass index (BMI) by Herbert and colleagues. The association between increased BMI and homozygosity for the minor allele was first observed in data from a genome-wide association scan of 86,604 SNPs in 923 related individuals from the Framingham Heart Study offspring cohort. The associ
Biträdande universitetslektor | Socionom, fil dr. i socialt arbete Kontaktinformation E-post: lisa [dot] andersson [at] soch [dot] lu [dot] seOrganisation Socialhögskolan Hämtställe: 31 WebbplatsLisa Anderssons profil i Lunds universitets forskningsportalAndra roller Universitetslektor Missbruk och beroendeJag är socionom och har lång och bred erfarenhet av professionellt socialt arbete från socia
https://www.soch.lu.se/lisa-andersson - 2026-10-08
Title: What is all the fuzz about? A FMCG brand portfolio case study of formalisation in the Front End of Innovation. Date of the seminar: 23 May 2017 Course: ENTN39 Master ́s Corporate Entrepreneurship and Innovation Internship and degree project (Master ́s thesis 15 ECTS) Authors: Mink Kempen and My Magnusson Supervisor: Joakim Winborg Examiner: Ass. Professor Sotaro Shibayama Keywords: De
Background: Whey protein increases postprandial serum insulin levels. This has been associated with increased serum levels of leucine, isoleucine, valine, lysine, threonine and the incretin hormone glucose-dependent insulinotropic polypeptide (GIP). We have examined the effects of these putative mediators of whey's action on insulin secretion from isolated mouse Langerhans islets. Methods: Mouse p
