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Investigating the Mechanism of Action of DNA Damage Response Inhibitors

Investigating the Mechanism of Action of DNA Damage Response Inhibitors Cancer is a complex, heterogenous, systemic disease. It is considered to be a leading cause of death worldwide. Currently, there is limited treatment for this disease and the field of oncology presents the highest percentage of failed trials (32%) for drugs in phase II and phase III, mainly due to lack of efficacy or safety.

Correlation between Surface and Tumour Motion in Lung Cancer - including Deep Learning Perspectives

Av de 70 000 personerna som blev diagnoserade med cancer i Sverige 2021, fick runt 4000 lungcancer. Lungcancer är vanligen elakartade celler som utgår från lungans slemhinna. Behandling innefattar oftast operation eller strålterapi, ibland i kombination med cellgifter eller immunterapi. Inför strålbehandling gör patienten en röntgenundersökning som ger bilder i tre dimensioner, en så kallad datorPurpose: The purpose of this master thesis was to retrospectively investigate correlation between surface and tumour motion in lung cancer patients, alongside deep learning applications of the results. Additional correlations such as age, tumour volume and anatomical placement of the tumour were also investigated. Materials and Methods: 48 lung cancer patients treated with Stereotactic Body Radia

När vården krisar och juridiken paniker

Med hänvisning till den rådande resursbristen och till den ökade efterfrågan av vård i allmänhet och intensivvård i synnerhet är prioriteringsbeslut något som många vårdgivare måste befatta sig med dagligen. Under år 2020 när coronapandemin svepte över oss och belastade sjukvården ytterligare så blev frågeställningarna rörande prioriteringsbeslut ännu mer aktuella än innan. Socialstyrelsen släpptIn regard to the current shortage of resources and the increasing demand for care in general and intensive care in particular, priority decisions are something that many healthcare providers have to deal with on a daily basis. In 2020, as the Corona pandemic swept across us and further burdened the healthcare system, the issues surrounding priority decisions became even more relevant than before.

A Quadrature Frequency Generation Chain for Direct-conversion Phased-array 5G Transceivers

The 5th generation (5G) has recently specified a new spectrum range, FR2- 5G New Radio (5G-NR), to provide higher spectral efficiency and channel capacity for ubiquitous cellular connectivity where the user ends can be in various types such as picocell stations, sensor nodes, cloud servers, hand-held devices, and so on. Due to the advantage of phased array antennas in performing beam-forming, and

Digitalization of Danish Daycare Institutions

Fatima, f, 34, parent: “It is a small home for our children. They spend many hours here. To us, it is not just daycare. We don’t just come here and drop off our children and say goodbye, then come back in a few hours. They have to feel that this is a home to them”. This ethnographic study of Danish daycares analyses how information is being shared between parents and daycare staff, how conflict is

Valorisation of baobab seed by-products: Bioprocessing and prebiotic potential of baobab seed press cake

Prebiotics are complex carbohydrates that are selectively fermented by beneficial gut bacteria, resulting in the production of health-promoting metabolites, such as organic acids like lactic acid, acetic acid, intermediates for butyrate and propionate. Baobab (Adansonia digitata) fruit contains many small seeds, often used for oil production. It’s by-product, baobab seed press cake, is rich in lig

"Adoption - om rätten till sitt ursprung"

Sammanfattning Uppsatsen behandlar det adopterade barnets rätt till kännedom om sitt ursprung. Frågan har diskuterats vid flertalet tillfällen och är nu aktuell på nytt, då den uppmärksammas i utredningen SOU 2009:61 – Modernare adoptionsregler. I utredningen föreslås en lagstadgad informationsskyldighet för adoptivföräldrar att informera barnet om dess ursprung. Denna bestämmelse skall sakna sankSummary This Graduate Thesis examines the adopted child´s right to knowledge of his or her origin. The biological parentage has been a subject of discussion throughout the history of adoption. In accordance with SOU 2009:61, the Committee has proposed a provision to be introduced requiring a person who has an adopted child, to inform the child of his or her biological origin. The provision is not

Reduction of Patient Dose in CT Adjustment of Tube Current to Patient Size

Motivationen med studien var den alldeles för höga stråldosen som används vid CTundersökningar. I de allra flesta fallen anpassas man inte rörströmmen efter patientens storlek och därmed får smalare patienter en onödigt hög stråldos. Målet var att reducera stråldosen till patienter som undersöks med datortomografi utan att minska på bildkvalité, genom att anpassa rörströmmen efter patientens stoIn this study we have investigated the possibilities of dose reduction in CT at a constant level of image quality by adjustment of the tube current to the phantom size. The motivation with the study is the high radiation doses to the patients and the increasing frequency of CT examinations and the variety of examinations in CT, and that the same tube current is used for different patient sizes. Ac

Acute heart failure: causes and outcomes by stages of chronic kidney disease and heartfailure phenotypes

Purpose: To investigate the relationship between heart failure (HF) and chronic kidney disease (CKD) by analysing the prevalence of different stages of CKD and other morbidities in patients admitted with acute heart failure (AHF), as well as readmissions and mortality.Introduction: Chronic kidney disease (CKD) is more prevalent among all phenotypes of HF patients than in the general population. It

Synnerligen grov misshandel - En utredning av gällande rätt och kritisk granskning av 3 kap. 6 § andra stycket brottsbalken

2010 års straffrätts reform initierades som en reaktion på att straffen för de grövsta formerna av misshandel endast dömdes ut i den nedre fjärdedelen av straffskalan. Reformen medförde bl.a. att straffskalan för grov misshandel i 3 kap. 6 § delades upp i två stycken, där andra stycket med en strängare straffskala på fyra till tio år skulle vara tillämplig för synnerligen grova fall. De grövsta faThe criminal reform of 2010 was initiated as a reaction to sentencing levels being concentrated to the lower quarter of the range of punishment for serious cases of assaults. The reform led to the division of the range of punishment for aggravated assault in chapter 3 article 6, to two separate subsections. The second subsection would apply a range of punishment between four to ten years applicabl

Unprecedented interest in Lund University’s recruitment – LTH welcomes AI researcher

Unprecedented interest in Lund University’s recruitment – LTH welcomes AI researcher Skip to main content We use cookies and other tracking technologies to improve the user experience on our website, to show you personalised content and targeted ads, and to analyse our website traffic. Cookie Policy . Essential cookies These cookies are necessary for the website to function and cannot be turned of

https://www.lth.se/english/article/unprecedented-interest-in-lund-universitys-recruitment-lth-welcomes-ai-researcher/ - 2026-04-20

program_EuroSoTL2017_0530

program_EuroSoTL2017_0530 Programme, EuroSoTL 2017, June 8-9, Lund University Thursday, June 8 2017 08.00- 09.00 Registration [Kårhuset: Foyer] 09.00- 09.15 Conference Opening: conference chair Katarina Mårtensson, Lund University [Kårhuset: Aulan, 2nd floor] 09.15- 10.15 Keynote speaker: Transforming higher education through student-staff co-creation of learning and teaching, Catherine Bovill, Un

https://konferens.ht.lu.se/fileadmin/_migrated/content_uploads/02_program_EuroSoTL2017_0530.pdf - 2026-05-16

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165 Abstract The chapter reviews evidence for the bodily mimesis hypothesis, which states that the evolution of language was preceded by an adaptation for improved volitional control of the body, giving our ancestors advantages in the domains of imi- tation, empathy, and gestural communication. Much of this evidence is also shared by other gesture-first theories of language origins, but they face

https://projekt.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_ccs/zlatev2014-final.pdf - 2026-05-18

Internship Guidelines 2023

Internship Guidelines 2023 1 (2) GUIDELINES 2023-09-28 Department of History Division for Human Rights Stu dies I lona Karppinen Internship coordinator Internship within the B.A. Programme in Human Rights This document outlines the purpose of the internship semester on the B.A. Programme in Human Rights Studies at Lund University. From this purpose follows a number of guidelines, which, as a gener

https://www.mrs.lu.se/fileadmin/user_upload/historiska/mrs/templates/Internship_Guidelines_2023.pdf - 2026-05-18

Existentiell ensamhet – att vara ensam omgiven av många? – Vetenskap och Hälsa

Existentiell ensamhet – att vara ensam omgiven av många? – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Existentiell ensamhet – att vara ensam omgiven av många? 2019-12-05 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. iStock/Cecilie_Arcurs Att inte längre

https://www.vetenskaphalsa.se/existentiell-ensamhet-att-vara-ensam-omgiven-av-manga/ - 2026-05-18

Microsoft Word - WP3 Carita Paradis EDITERAD15 aug 2003.doc

Microsoft Word - WP3 Carita Paradis EDITERAD15 aug 2003.doc Where does metonymy stop? Senses, facets and active zones CARITA PARADIS 1 Introduction Within the framework of Cognitive Linguistics both metonymy and metaphor are seen as pervasive phenomena in thought and language. They are, however, different conceptualizations of experience. Metaphorization, such as ‘Love is a journey’, involves the

https://www.sol.lu.se/fileadmin/media/forskning/workingpapers/engelska/vol03/Paradis-Wheredoesmetonymystop.pdf - 2026-05-18

Forskarutbildningsenkäten handledare 2020

Forskarutbildningsenkäten handledare 2020 Forskarutbildningsenkäten handledare 2020 SAMMANFATTNING John Jönsson, Avdelningen för kvalitetsstöd, LTH jo5480jo Textruta Dnr U 2021/121 1 Innehåll 2 1. Inledning Föreliggande rapport redovisar resultatet av Forskarutbildningsenkäten handledare som genomfördes vid LTH under hösten 2020. Syftet med enkäten är att följa upp handledarnas förutsättningar ino

https://www.lth.se/fileadmin/lth/anstallda/kvalitet/Resultat_i_kvalitetssystemet/Uppfoeljning_FU/Resultat_forskarutbildningen/Rapport_handledarenkaeten_LTH_2020.pdf - 2026-05-18