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Ring-Contraction of sugar-derived epoxy alcohols, functionalised in position 1 and 6, by treatment with lithium bromide and N, N, N', N'-tetramethylurea in refluxing toluene gave enantiomerically pure a,b-unsaturated aldehydes of furanosides. O-Glycosidic epoxy alcohols gave only one, easily purified, aldehyde in approximately 30-60% yield depending on the substitution pattern. C-Glycosidic epoxy
Maria Nyman The Borders of travelling. Russia in Swedish travel accounts during the 18th century. The primary objective of this study concerns how culturally created images of the Same and the Other, is expressed in descriptions of a journey, a sojourn someplace else. More specifically, the dissertation investigates how a number of Swedes, travelling during the eighteenth- and early nineteenth cen
Background: Sweden is a high endemic region for multiple sclerosis (MS), a neurologic disorder characterized by repeated inflammatory episodes affecting the CNS. The disease has its peak age of onset at approximately 30 years and affects women twice as often as men. The young age of onset makes MS one of the major causes of reduced capacity to work due to neurologic disease in Western society. Nat
Brown C, Hasson H, Thyselius V, Almborg A-H. Post-stroke depression and functional independence: a conundrum. Acta Neurol Scand: DOI: 10.1111/j.1600-0404.2011.01595.x. © 2011 John Wiley & Sons A/S. Objectives - People who suffer a stroke are at risk of developing post-stroke depression (PSD). Not only does this lower their quality of life but it also increases their risk of another stroke or d
Objective: This study aimed to evaluate the outcome and predisposing factors related to perioperative bleeding in patients treated with endovascular aneurysm repair (VAR) for ruptured and non-ruptured abdominal aortic aneurysm (AAA). Design: This was a retrospective cohort study. Methods: A total of 525 consecutive patients (73% elective) with AAA underwent EVAR at two vascular centres from 2008 t
Salutogenesis focuses on how come people recover or stay well. The answer was described to be a Sense of Coherence (SOC). SOC is a global orientation which contributes to how flexible coping strategies are chosen. The SOC concept was operationalized in The Sense of Coherence Scale (SOC-29). The questionnaire address to what extent life is perceived as comprehensible, manageable, and meaningful. T
INTRODUCTION Stroke is a serious neurological disease which may lead to death and severe disability [1, 2]. There are two major types of stroke: ischemic and hemorrhagic stroke. Both are associated with disruption of blood flow to a part of the brain with rapid depletion of cellular energy and oxygen, resulting in ionic disturbances and eventually neuronal cell death [3]. The pathologic process t
The thesis is based on applied research, rather closed to industrial development. The developed simulation model, for pre-design of evaporative gas turbine cycles, has been validated in a 600 kW pilot plant and in rebuilt turbo-charged diesel engines. Besides of the work with the thesis including theoretical modelling and hardware development concerning wet cycles, the work has also resulted in th
Popular Abstract in Swedish Rehabilitering har sedan länge varit en viktig och naturlig del av behandlingen för personer med reumatiska sjukdomar. I denna doktorsavhandling om teambaserad rehabilitering för personer med kroniska reumatiska ledsjukdomar ges en uppdatering av kunskapsläget liksom en historisk bakgrund. De vetenskapliga resultat som redovisas i avhandlingen visar i korthet på följandThe aim of this thesis was to study outcome and evaluation of rheumatological multidisciplinary team rehabilitation programmes in patients with chronic inflammatory arthritis (CIA); rheumatoid arthritis (RA), ankylosing spondylitis, psoriatic arthritis and other spondyloarthritides, and to analyse health care utilization over the last decade in patients with RA. In Study I the outcome of an 18 da
AIMS: Heparin is the preferred choice of anticoagulant in percutaneous coronary intervention (PCI) for acute myocardial infarction (MI). An established dosage of heparin has not yet been determined, but treatment may be optimized through monitoring of activated clotting time (ACT). The aim of this study was to determine the relationship between heparin dose or ACT with a composite outcome of death
BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is the most common severe chronic disease in primary care. It is typically diagnosed at a late stage, and it is also difficult to predict its trajectory and hence to tailor treatment and rehabilitation. The overall aim is to study determinants of exacerbations of COPD treated in primary care and to study, if the prognosis is related to patie
Background: The quality of the total mesorectal excision specimen in rectal cancer surgery is assessed with a three-tier grade (mesorectal, intramesorectal and muscularis propria). This study aimed to analyse the prognostic impact of the total mesorectal excision grade on survival, and to identify risk factors for intramesorectal and muscularis propria resection in a population-based setting. Meth
BACKGROUND: Sexual violence against older adults in humanitarian settings is poorly documented, leading to gaps in prevention and delivery of support services. This study aimed to document differences in assault characteristics between younger and older adults, by sex and displacement and disability status and region. METHODS: This retrospective, descriptive observational, multi-country study incl
Background and purpose: Hormone-receptor-positive/HER2-negative (HR+/HER2-) early-stage breast cancers (EBCs) display heterogenous responses to neoadjuvant chemotherapy (NACT) warranting biomarkers to tailor optimal treatment for individual patients. Patients/material and methods: Women with HR+/HER2-EBC (N = 178) included in the Swedish Sweden Cancerome Analysis Network-Breast (SCAN-B) population
Background and purpose: Stereotactic radiosurgery (SRS) requires high positional accuracy to safely deliver large doses. This study evaluated an integrated surface- and image-guided radiotherapy (SGRT-IGRT) system by analysing (1) the agreement between thermo-optical and stereoscopic X-ray positioning, and (2) the impact of intra-fractional workflows on treatment accuracy and time. Materials and m
Bol. Soc. Mat. Mexicana (3) Vol. 19, 2013 TWO APPLICATIONS OF PERMUTATION TESTS IN BIOSTASTICS LUIS LEÓN-NOVELO, KAISA M. KEMPPAINEN, ALEXANDRIA ARDISONNE, AUSTIN DAVIS-RICHARDSON, JENNIE FAGEN, KELSEY GANO, ERIC W. TRIPLETT, AND TEDDY STUDY GROUP ABSTRACT. We show two examples of how we answer biological questions by converting them into statistical hypothesis testing problems. We consider gene a
Platform for strategic work 2023-2024 Platform for strategic work 2023–2024 RESEARCH, EDUCATION AND INNOVATION – TODAY AND FOR THE FUTURE Platform for strategic work 2023–2024 RESEARCH, EDUCATION AND INNOVATION – TODAY AND FOR THE FUTURE The world around us is significantly more unpredictable and volatile than before and the conditions are more complex. Therefore, the University needs to act in ne
The acoustic emission that is detectable in the forming of complex thin part plates contains information about the quality of the pressed plates. The information can be used as process control and to filter out advanced thin plates with defects such as cracks. The article describes the results obtained in a try-out pressing process in special developed punch-die pairs with different pressing
Studying gene-lifestyle interaction may help to identify lifestyle factors that modify genetic susceptibility and uncover genetic loci exerting important subgroup effects. Adequately powered studies with prospective, unbiased, standardised assessment of key behavioural factors for gene-lifestyle studies are lacking. This case-cohort study aims to investigate how genetic and potentially modifiable
Leachate treatment is one of the major environmental issues faced by landfill owners. One promising method for reduction of pollutant discharge is reverse osmosis (RO). RO technology was tested at a pilot plant at Hedeskoga Landfill in southern Sweden. This landfill receives municipal solid waste (MSW) and industrial, commercial and institutional (IC&I) waste, and produces about 3000 m3/ha of
