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Background: In 2014 the Swedish government assigned to The Public Health Agency of Sweden to conduct studies to evaluate optimal use of existing antibiotic agents. The aim is to optimize drug use and dosing regimens to improve the clinical efficacy. The present study was selected following a structured prioritizing process by independent experts. Methods: This phase IV study is a randomized, open-

Anemia is already present in patients with moderate renal failure and is a major cause of the decline in exercise capacity seen in these patients. We examined the effects of erythropoietin (EPO) treatment in 12 predialytic uremic patients (EPO group: mean age 46 ± 12 years; 6 men, 6 women) with a mean glomerular filtration rate (GFR) of 10 ± 4 ml/min x 1.73 m2. These patients were compared to a co

The aim of this study is to assess personal exposure to Particle Number Concentrations (PNC) in four size ranges between 0.3 and 10 μm, and particulate matter (PM1; PM2.5; PM4; PM10) in order to evaluate possible genotoxic effects through a comet assay in buccal cells. A convenience cohort of 30 individuals from a Brazilian medium-sized city was selected. These individuals aged between 20 and 61 a

Background: The implementation of screening programmes in Sweden during the mid-1990s increased the number of small node-negative breast cancers. In this era before staging by sentinel node biopsy, routine axillary dissection for staging of early breast cancer was questioned owing to the increased morbidity and lack of perceived benefit. The long-term risk of axillary recurrence when axillary stag

Experimental studies suggest that hepatocyte growth factor (HGF) and its transmembrane tyrosine kinase receptor, Met, in part also relying on Akt kinase activity, mediate radioresistance. We investigated the importance of these biomarkers for the risk of ipsilateral breast tumour recurrence (IBTR) after adjuvant radiotherapy (RT) in primary breast cancer. HGF, phosphorylated Met (pMet) and phospho

English oak (Quercus robur) and European beech (Fagus sylvatica) are amongst the most common tree species growing in Europe, influencing the annual biogenic volatile organic compound (BVOC) budget in this region. Studies have shown great variability in the emissions from these tree species, originating from both genetic variability and differences in climatic conditions between study sites. In thi

Introduction: Hip fractures are commonly diagnosed by plain radiography. When a patient presents with negative radiographs and high clinical suspicion of fracture, guidelines recommend proceeding with magnetic resonance imaging (MRI) to diagnose the patient. The aim of this study was to assess the use of MRI in diagnosing hip fractures following trauma to the hip and describe clinical outcome afte

Background: Falls and fear of falling (FOF) are common in persons with late effects of polio, but there is limited knowledge of associated factors. Objective: To determine how knee muscle strength, dynamic balance, and gait performance (adjusted for gender, age, and body mass index) are associated with falls and FOF in persons with late effects of polio. Design: A cross-sectional study. Setting: A

OBJECTIVE: Cardiovascular disease (CVD) risk prediction represents an increasing clinical challenge in the treatment of diabetes. We used a panel of vascular imaging, functional assessments, and biomarkers reflecting different disease mechanisms to identify clinically useful markers of risk for cardiovascular (CV) events in subjects with type 2 diabetes (T2D) with or without manifest CVD.RESEARCH

Titel: Diskonteringsräntan vid nedskrivning av goodwill - En jämförelsestudie av marknadsmässiga bedömningar Seminariedatum: 2014-05-23 Ämne/kurs: FEKN90, Företagsekonomi: Examensarbete i Corporate Finance på magisternivå. 30hp. Författare: Victor Håkansson och Anton Persson Handledare: Erling Green Nyckelord: Goodwill, nedskrivningsprövning, diskonteringsränta, marknadsmässiga bedömningar ocTitle: The discount rate used in the impairment testing of goodwill – A comparison of market-based assessments Seminar date: 2014-05-23 Course: FEKN90, Business Administration: Master Thesis in Corporate Finance, 30 HP Authors: Victor Håkansson and Anton Persson Advisor: Erling Green Key words: Goodwill, impairment testing, discount rate, market-based assessments and IAS 36. Purpose: The pur

For historical reasons, Swedish railways use 15 kV/16? Hz overhead contact lines for train traction, while the most common standard worldwide is 25 kV/50-60 Hz. This leads to higher investment costs for railway conversions and expansions, and to greater energy losses in the distribution of electricity to the trains. Yet to get away from these drawbacks by investing in a 25 kV/50 Hz overhead contac

Skattelagstiftning styrs av principer, som ibland kan säga emot varandra och då behöva vägas mot varandra. I förarbeten redogör lagstiftaren för hur denna bedömning ser ut, och det är möjligt att genom förarbeten analysera vilka principer lagstiftaren behandlar, hur de behandlas och hur de vägs mot varandra. Det finns olika sätt att dela in skatterättsliga principer; ett sätt är att dela in dem i Tax law is governed by principles, that sometimes may contradict each other and then need to be weighed against each other. In preparatory works the lawmaker gives their account for how the assessment of principles looks like, and it’s possible through preparatory works to analyse which principles the lawmaker considers, how they’re considered, and how they’re weighed against each other. There are

Introduction: Side-stream residue, oat okara, from the oat-milk production contains valuable nutrients but possesses a high risk of microbial spoilage. Valorisation of oat okara is therefore important to make sure that the oat beverage production stays sustainable. In this project, High-pressure processing (HPP), heat treatment and Lactobacillus fermentation have been evaluated for their microbial

Med det ökande behovet att minska användandet av fossila bränslen så är metaller ett utmärkt alternativ för att elektrifiera samhället. Koppar är en av de viktigaste metallerna på grund av de stora mängder som förekommer naturligt på vår planet. Det är även på grund av dess utmärkta egenskaper. Sedan koppar upptäckes för flera århundraden sedan har användandet fortsatt att öka. Koppar och dess egeCopper and copper alloys are important material systems for the electrification of society. The high workability of the materials makes them appropriate in numerous different applications which require highly conductive properties. One main advantage of Cu and Cu-bearing alloys is the eminent ability to be repeatedly recycled without losing the advantageous properties. This raises the question whe

Guðrún Guðjónsdóttir Climate change is having a great impact on the fragile High Latitude environment where warming is occurring at a rate at least double the global average. It is urgent to understand the relationship between climate and vegetation cover, which is playing an important role, as a carbon sink, for biodiversity, and for protecting against natural hazards. Less studied but equally i

Understanding and being able to quantify sitting postures is a central asset in car safety evaluations. This is due to the fact that passengers can choose a range of different sitting positions. Studying and understanding how passengers choose to sit to obtain some comfort is important for increased safety in futures cars and is particularly challenging facing a heterogeneous population. Data is a

Genom att minska mängden planktivor och bottenlevande fisk (reduktionsfiske eller biomanipulation) kan vattenkvalitén och den ekologiska statusen i övergödda sjöar förbättras. Om metoden utförs effektivt ger den positiva effekter på siktdjup, algmängd samt biodiversitet vilket ökar möjligheterna för rekreation och dricksvatten. En viktig upptäckt vid reduktionsfisken är att bottenlevande fisk har Biomanipulation, i.e. to reduced planktivorous- and benthivorous fish in order to receive changes in the trophic structure has been a successful method to improve water quality and the ecological status in eutrophic lakes. The initial idea was to increase the abundance of large zooplankton and thus to cause a trophic cascade with reduced algal biomass. Many studies failed to observe an increase of

Studien syftar till att ta fram rekommendationer och råd kring hur klimatpåverkan från anläggningsentreprenader kan beräknas och redovisas. Detta genom att undersöka hur andra aktörer inom branschen agerar i frågan och kartlägga modeller och verktyg för klimatberäkningar. Studien har utförts som en kombination av kvalitativa och kvantitativa forskningsmetoder, vilket kan liknas vid begreppet triaThe purpose of the study is to come up with recommendations and advice on how to calculate and present the climate impact from construction works. This will be implemented by examining how other actors within the construction industry is acting on the issue and examine models and tools for climate calculations. The study was conducted as a combination of qualitative and quantitative research meth

Popular science summary Has climate change influenced flowering time of coltsfoot? Phenological events such as the onset of flowering during the spring are among the most sensitive indicators of climate change. Hence, phenological data have recently emerged as effective tools for studying the impact of climate change on species and ecosystems. In this study, I used records from herbaria and pub

Background: Road-traffic noise may influence the development of cardiovascular events such as stroke and myocardial infarction, but etiological mechanisms remain unclear. This study aimed to assess the relationship between long-term road-traffic noise exposure and coronary atherosclerosis in Sweden. Methods: In the Swedish CArdioPulmonary bioImage Study (SCAPIS) cohort, including 30,154 subjects a