Filetype
A causal inference framework was developed to investigate crop responses to agricultural drought by integrating meteorological data, Sentinel-2-derived data, and soil property maps. To account for crop rotation, soil, and topographical variables, propensity score matching was employed to estimate drought-induced yield losses at the field level for selected periods. The Plant Phenology Index (PPI)
Background/Objectives: Intraoperative frozen biopsies are essential during surgery for Hirschsprung’s disease (HD). However, this method has several limitations with the need for a faster and real-time diagnostic alternative. For this, consistent histoanatomical and morphometric differences between aganglionic and ganglionic bowel must be established. The primary objective was to compare dimension
Objectives: Many Japanese adults experience poor sleep quality. Prolonged sedentary behavior negatively affects health, including sleep-associated problems. We investigated the association between sedentary behavior and sleep quality among urban white-collar workers in Japan with metabolic syndrome or at risk of metabolic syndrome, a population thought to have particularly prolonged sedentary time
Objective: Although rare, malignant ovarian germ cell tumors (MOGCTs) account for 70 % of ovarian malignancies in women younger than 30 years. Given the rarity of MOGCTs and the limited population-based data, this study aims to examine national treatment patterns and survival in women with MOGCTs, with a focus on fertility-sparing surgery. Methods: This nationwide population-based study included a
Background: Neoadjuvant cisplatin-based combination chemotherapy (NAC) is standard perioperative treatment of patients with muscle-invasive urothelial bladder cancer (MIBC); however, about half of the patients experience recurrence of the disease. Biomarkers for response and survival represent an unmet medical need. We used tumor specimens from transurethral resections of the bladder to explore ge
Despite significant progress in oncology research, pancreatic cancer remains inherently difficult to treat, and the mechanisms underlying therapeutic resistance remain unresolved. Decorin (DCN), a member of the family of small leucine-rich proteoglycans, has emerged as a versatile actor in various malignant diseases. The aim of this study was to further explore the potential clinical significance
One of the major recent breakthroughs has been the discovery of the last major merger to happen in the history of the Milky Way. Around 10 Gyr ago, the galaxy Gaia Enceladus with an estimated ∼10% of the Milky Way mass, fell into the potential of our Galaxy, bringing a large amount of stars that can be identified through their unique chemical and kinematic signatures. Simulations have long predict
Eddy covariance measurement of species that are co-emitted with carbon dioxide (CO2), such as carbon monoxide (CO) and nitrogen oxides NO and NO2 (NOx), provides an opportunity to attribute a net flux to individual source or sink categories. We present eight months of continuous simultaneous measurements of fluxes (F) of CO2, CO, NOx, methane (CH4), and nitrous oxide (N2O) from a tall tower (112 m
Background: Previously untreated patients with severe hemophilia A exposed to factor (F)VIII are at risk of developing high-titer inhibitors. Traditionally, such children were tried on immune tolerance induction (ITI). With availability of nonfactor therapies, recommendations regarding whether to continue trying ITI and how are lacking. Objectives: To provide data to address these questions, we re
Phosphorus-driven eutrophication of surface waters persists across Europe and Water Framework Directive (WFD) implementation is slow. Calls for better management approaches advocate for involving multiple stakeholders, considering social, ecological and technological drivers, and applying ‘multi-level’ or ‘multi-scalar’ approaches. However, multi-level approaches rarely apply ‘scales’ and ‘levels’
Mild traumatic brain injury (mTBI) is a frequent but underreported consequence of professional cycling crashes, yet current helmet testing standards primarily simulate head-first impacts, and their representation of real-world head impact scenarios is unclear. This study explores crash typology of professional cycling crashes involving head-ground contact through systematic video analysis of 128 h
CONTEXT: Mild autonomous cortisol secretion (MACS) is associated with increased mortality in patients with adrenal incidentalomas (AI), but little is known regarding the potential risk associated with non-functional adrenal adenomas (NFAA), which constitute the majority of AI.OBJECTIVE: Compare mortality risk in patients with NFAA, and different levels of MACS, to matched controls.METHOD: This was
BackgroundDuring recent years FLASH radiotherapy (FLASH-RT) has shown promising results in radiation oncology, with the potential to spare normal tissue while maintaining the antitumor effects. The high speed of the FLASH-RT delivery increases the need for fast and precise motion monitoring to avoid underdosing the target. Surface guided radiotherapy (SGRT) uses surface imaging (SI) to render a 3D
Purpose: Artifacts impacting the imaged tumor volume can be seen in conventional three-dimensional CT (3DCT) scans for planning of lung cancer radiotherapy but can be reduced with the use of respiration-correlated imaging, i.e., 4DCT or breathhold CT (BHCT) scans. The aim of this study was to compare delineated gross tumor volume (GTV) sizes in 3DCT, 4DCT, and BHCT scans of patients with lung tumo
Biological aerosol particles affect human health, are essential for microbial and gene dispersal, and have been proposed as important agents for atmospheric processes. However, the abundance and size distributions of atmospheric biological particles are largely unknown. In this study we used a laser-induced fluorescence instrument to measure fluorescent biological aerosol particle (FBAP) concentra
Background: Physical education (PE) teachers in practically all countries are expected to help their students develop movement capability. To achieve this objective, teachers need certain knowledge and competencies. The question of how PE teachers should develop their capacities to achieve this task has received only limited research attention. Aim: The broad objective of this paper is to contribu
Mantle cell lymphoma (MCL) is a B-cell malignancy currently considered incurable. Although some patients obtain prolonged remission after first-line chemoimmunotherapy, many will need several treatment lines. Here, we present a nationwide assessment of treatment strategies, time to progression and survival in MCL. All patients diagnosed with MCL 2006-2018 were identified in the Swedish Lymphoma Re
The growing demand to lower greenhouse gas emissions and transition from fossil fuels, has put methanol in the spotlight. Methanol can be produced from renewable sources and has the property of burning almost soot-free in compression ignition (CI) engines. Consequently, there has been a notable increase in research and development activities directed towards exploring methanol as a viable substitu
Gambling disorder can be treated with cognitive behavioral therapy (CBT), but treatment is under-dimensioned in many settings. For example, in Sweden, a setting with mixed responsibility for addiction treatment between health care and social services, treatment for gambling disorder has only recently been introduced in the responsibilities of public institutions. After the introduction of gambling
Popular Abstract in Swedish I många tekniska applikationer vill man på något sätt överföra elektrisk energi till mekanisk energi eller tvärtom. Det kan till exempel handla om att med hjälp av en elektrisk signal generera eller mäta rörelse. Så kallade elektroaktiva material har den speciella egenskapen att överföringen mellan elektrisk och mekanisk energi sker direkt. I ett piezoelektriskt materiaThe electroactive polymer materials considered in this work react to electric stimuli by producing deformations. In some cases, the electrically induced deformations are moderate, while in other cases they can be very large and the specimen is stretched to more than twice its original length. The latter response is seen in so called dielectric elastomer actuators (DEA). The possibility of very lar
