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Brevmall 4 (9) Contract Research Agreement made between Lund University ("LU"), registration no. 202100-3211, with address P. O. Box 117, SE-221 00 Lund, Sweden; and [organisation name] (“[abbreviation of organisation name]”) ("[XX]"), organisation registration no. [organisation registration no.], duly organised under the laws of [country], with address [address] ; each also referred to as a "Part
Purpose: Hematoma volume is the strongest predictor of patient outcome after intracerebral hemorrhage (ICH). The aim of this study was to validate novel fully automated software for quantification of ICH volume on non-contrast computed tomography (CT). Methods: The population was defined from the Swedish Stroke Register (RS) and included all patients with an ICH diagnosis during 2016–2019 in Regio
OBJECTIVE: To investigate potential associations between individual and country-level factors and medicalization of birth in 15 European countries during the COVID-19 pandemic.METHODS: Online anonymous survey of women who gave birth in 2020-2021. Multivariable multilevel logistic regression models estimating associations between indicators of medicalization (cesarean, instrumental vaginal birth [I
Rationale: Galectin-3 (Gal-3) drives fibrosis during chronic lung injury, however, its role in acute lung injury (ALI) remains unknown. Effective pharmacological therapies available for ALI are limited; identifying novel concepts in treatment is essential. GB0139 is a Gal-3 inhibitor currently under clinical investigation for the treatment of idiopathic pulmonary fibrosis. We investigate the role
Introduction To investigate the current experience of the ARM-Net Consortium in the management of epididymo-orchitis (EO) in patients with anorectal malformations (ARMs), and to identify specific risk factors and the need for urological care involvement. Materials and Methods We retrospectively collected data of EO in patients with ARM between 2015 and 2019. Data on urological aspects, ARM type,
BackgroundWomen are at a greater risk of a major adverse cardiovascular event (MACE) after percutaneous coronary intervention than men. A history of preterm delivery is a female-specific risk factor for coronary artery disease, but its relevance in the treatment of coronary artery disease is unknown.ObjectivesThe purpose of this study was to analyze the association between a history of preterm del
OBJECTIVE: To verify if (123)I-FP-CIT, DaTSCAN(®) can differentiate early stages of Parkinson's disease (PD) as well as patients with Atypical Parkinsonian syndromes (APS) from manifest Parkinson's disease.METHODS: 128 consecutive patients were investigated with (123)I-FP-CIT SPECT during a 4-year period. All patients were diagnosed according to the established consensus criteria for diagnosis of
For many years, universities represented the ultimate outpost for professional autonomy in Western democracies. Despite little insight into the professional practices of scholars or administrators, governments provided the academic profession with extensive discretion, including the freedom to regulate qualifications for positions, terms for promotion, quality standards, goals, performance indicat
BackgroundThe novel Motor Imagery to Facilitate Sensorimotor Re-Learning (MOTIFS) training model, which began development in 2018, integrates psychological training into physical rehabilitation in knee-injured people.ObjectiveThis qualitative interview study aims to understand, interpret, and describe how physical therapists perceive using the MOTIFS Model.MethodsOne-on-one semi-structured intervi
Investigating the optical properties of various chemical compounds using UV-vis spectrophotometers is an essential part of education in chemistry. However, commercial spectrophotometers are usually treated as "magic black boxes", where the dominant majority of optical elements are hidden "under the hood". This often limits understanding of the mechanisms behind the generation of spectral curves, w
STUDY DESIGN: Cross-sectional. BACKGROUND: The association between muscle function and lack of knee confidence in people with anterior cruciate ligament (ACL) injury has not been well investigated. Such knowledge would help in the design of training programs for this population. OBJECTIVE: To investigate associations between self-reported knee confidence and muscle function in patients with ACL in
Objective: To evaluate the influence of implant and prosthetic components on peri-implant tissue health. A further aim was to evaluate peri-implant soft-tissue changes following surgical peri-implantitis treatment. Materials and methods: Group discussions based on two systematic reviews (SR) and one critical review (CR) addressed (i) the influence of implant material and surface characteristics on
Bile acids (BAs) play different roles in cancer development. Some are carcinogenic and BA signaling is also involved in various metabolic, inflammatory and immune-related processes. The liver is the primary site of BA synthesis. Liver dysfunction and microbiome compositional changes, such as during hepatocellular carcinoma (HCC) development, may modulate BA metabolism increasing concentration of c
Purpose: The enhanced recovery after surgery (ERAS) program expedites patient recovery after major surgery. This study aimed to investigate the role of the triad of procalcitonin (PCT), C-reactive protein (CRP), and white blood cells (WBC) trajectories as a predictive biomarker for the anastomotic leak (AL) after colorectal surgery. Method: Patients who had colorectal anastomosis were prospectivel
Every day we perform several recurring activities with little or no guidance from conscious intention. These daily and repetitive actions are often referred to as habits. The situation with Covid-19 has had a dramatic impact on how we go about our daily lives and how we interact with other persons at home or at work. In relation to working life one specific aspect was that many office workers were
BACKGROUND: Patients with major depressive disorder (MDD) may display elevated plasma levels of pro-inflammatory substances. Although the underlying mechanisms are unknown, inflammation has been proposed to play a direct role in the generation of depressive symptoms. Skeletal muscle is a potent producer of cytokines, and physical exercise has been suggested to alleviate symptoms of depression. In
AIM: To find out if ILT can be used as radical treatment of breast cancer. METHOD: Twenty-four patients, aged 39-84 (mean 61), with invasive breast cancer were treated with ILT. All underwent mammography, ultrasound and core biopsy before treatment. The tumour was an invasive ductal carcinoma in 15 patients, a lobular carcinoma in eight and lobular-ductal cancer in one. Average tumour diameter was
Appreciation and production of musical rhythm is a human universal and, as with other human capacities, it is imperative to understand the extent of our capacity to perceive and produce rhythm. This thesis presents my work on the cognitive and perceptual aspects of rhythm perception and production at a slow tempi. In Paper I I establish that rhythm production, such as keeping the beat to a metron
