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Background: The risk of dementia is increased in patients with atrial fibrillation (AF). Objective: To study relevant co-morbidities and incident dementia (vascular dementia, Alzheimers disease, other dementia and all dementia) in AF patients. Methods: All adults (n = 537,513) ≥45 years diagnosed with AF in hospitals in Sweden 1998–2012 were included. Cox regression was used to estimate hazard rat

The nonionic low-osmolar contrast medium iohexol was used as marker of glomerular filtration rate (GFR) in 53 patients with stable renal function (group I: n = 32, group II: n = 21). All the patients had clearance values < or = 30 ml.min-1.1.73 m-2 body surface; 40 patients < 20 ml.min-1.1.73 m-2 body surface. Simultaneous determinations of renal clearance and plasma clearance, both as slope clear

Background Neighborhood deprivation has been found associated with both type 2 diabetes and lung cancer. The aim of this study was to examine the potential association between neighborhood deprivation and lung cancer incidence or mortality in individuals diagnosed with type 2 diabetes. The results may identify a new risk or prognostic factor for lung cancer in this important subgroup and help deve

AIM: Breath-holding spells (BHS) are common in children, but evidence-based clinical guidelines are lacking. We investigated a large population-based cohort of BHS patients, to propose a refined description of typical BHS and guidelines for its management.METHODS: In a cross-sectional retrospective study, patients diagnosed with BHS in Southern Sweden 2004-2018 were recruited. Disease characterist

Enzymoblotting is a technique for the detection of electrophoretically separated enzymes after transfer to nitrocellulose (NC) membranes and subsequent incubation with suitable substrates. After agarose gel electrophoresis or isoelectric focusing in ultrathin polyacrylamide gels, blotting of the separated proteins/enzymes to NC membranes was performed by capillary forces for 30 min. Hydrolases, e.

EU countries have committed to taking national measures to reduce the average energy use of residential buildings by 16% by 2030 and 20–22% by 2035. Each country has decided how to achieve this and which buildings to focus on. However, certain categories of residential buildings, including historical buildings but also second homes, may be exempt from these obligations. In Sweden, second homes con

Deep electrification powered by renewable sources has emerged as a pivotal strategy for achieving ambitious CO2 emission reduction targets. However, the true impact of electrification on decarbonization remains inadequately measured because the whole energy chain has not yet been fully considered. This study combines Societal Exergy Accounting and Logarithmic Mean Divisia decomposition analysis to

Objective To investigate the relation between preterm birth (gestational age <37 weeks) and risk of CKD from childhood into mid-adulthood. Design National cohort study. Setting Sweden. Participants 4 186 615 singleton live births in Sweden during 1973-2014. Exposures Gestational age at birth, identified from nationwide birth records in the Swedish birth registry. Main outcome measures CKD, identif

PURPOSE: The study investigated curative radiation therapy (RT) plus cisplatin versus RT plus cetuximab in patients with locoregionally advanced head and neck squamous cell carcinoma (HNSCC).METHODS AND MATERIALS: This was a Swedish multicenter randomized phase 3 study. Included patients were randomized 1:1. Patients with T3-T4 tumors underwent a second randomization 1:1 between a final RT dose of

Study Design Controlled laboratory study; cross-sectional. Background Postural control following anterior cruciate ligament reconstruction (ACLR) primarily has been investigated during static single-leg balance tasks. Little is known about dynamic postural control deficits post-ACLR. Objectives To compare dynamic postural control (bilaterally) in persons who have undergone ACLR and healthy control

We determined the concentration of markers in cartilage and synovium metabolism in the synovial fluid (SF) of the knee of young beagle dogs with slowly progressive osteoarthrosis. Osteoarthrosis (OA) was induced by a tibial 30°valgus osteotomy to the right hindlimb of 16 dogs. The contralateral knee served as control. The animals were killed 7 (group I) and 18 months (group II) after operation. Th

Objectives:This thesis aims to provide an overview of the epidemiology of AAV in southern Sweden, to evaluate different classification criteria in AAV. In addition we study if infection is a risk factor for later development of AAV comparing patients with AAV with a matched population cohort and to examine the occurrence of severe infections as an outcome in AAV. Methods:All adult patients diagnos

Aims/hypothesis: The rapid remission of type 2 diabetes by a diet very low in energy correlates with a marked improvement in glucose-stimulated insulin secretion (GSIS), emphasising the role of beta cell dysfunction in the early stages of the disease. In search of novel mechanisms of beta cell dysfunction after long-term exposure to mild to severe glucotoxic conditions, we extensively characterise

Extremophiles, the microorganisms inhabiting different extreme environments char-acterized by high or low temperature, high or low pH, high salt concentration, high pressure, high radiation, etc. or combinations thereof, have developed unique strate-gies for adapting and thriving in such environments. Studies on extremophiles have been pursued with great interest to determine the mechanisms of ada

The aim of this study is to characterize atrial fibrillatory rate (AFR) extracted from a cohort of continuously monitored atrial fibrillation (AF) patients as function of episode duration and onset time. The f-wave signal used to compute the AFR was extracted from a single lead ECG strip of the AF episodes stored in an Implantable Cardiac Monitor (ICM) in a cohort of 99 patients. The f-wave signal

This paper documents the seventeenth data release (DR17) from the Sloan Digital Sky Surveys; the fifth and final release from the fourth phase (SDSS-IV). DR17 contains the complete release of the Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) survey, which reached its goal of surveying over 10,000 nearby galaxies. The complete release of the MaNGA Stellar Library (MaStar) accompanies

Background: Little is known about the relative impact of the preoperative symptoms rest pain and tissue loss, and of the arterial segment revascularized, on amputation rate and mortality in patients with chronic limb-threatening ischemia (CLTI). We wanted to investigate this topic further. Method: This population-based observational cohort study involved 10 419 patients revascularized for CLTI in

Det har sagts att alla arkitekturepoker brukar nå sitt bottenmärke någonstans runt 30 år. Under en praktik på ett arkitektkontor upplevde jag det på egen hand när jag arbetade med ett område i Stockholm. Strategin för området är att riva stora delar av dess bebyggelse från 80- och 90-talet. Jag uppfattar strategin som ett uttryck för en allmän impopularitet av arkitekturen från denna period — den

Förlust av biodiversitet är ett av de största globala miljöbetingade problemen idag. Arter står inför ökande och potentiellt synergistiska hot från markomvandling och överexploatering av naturresurser, från globala såväl som lokala socioekonomiska krafter. Populationerna av ryggradsdjur har mellan år 1970 och 2016 visat på en global genomsnittlig minskning på 68 procent. Större djur, s.k. megafaun

Med sin ökade tillgänglighet på den kommersiella marknaden har eye-tracking blivit ett allmänt tillgängligt system för att analysera ögonrörelser. Detta har öppnat upp för nya möjligheter för utvärdering av usability inom humancomputer interaction, som tidigare har varit dyrt, tidskrävande och ofta utfört baserat på dåligt dokumenterade standarder och mål. Tidigare forskning har visat att eye-tracWith its increased availability on the commercial market, eye-tracking has become a widely accessible system for analysing eye-movements. This has opened up new possibilities in evaluation of usability in human-computer interaction, which has had a history of being expensive, time-consuming and often performed based on poorly documented standards and objectives. Previous research has indicated the