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Association of Preterm Birth with Risk of Ischemic Heart Disease in Adulthood

Importance: Preterm birth has previously been associated with increased risks of hypertension and diabetes, but not ischemic heart disease (IHD), in adulthood. The reasons for this lack of association with IHD despite associations with its risk factors have been elusive, but may be associated with methodologic issues, such as survivor bias, in prior studies. Objective: To determine whether preterm

Tissue reactions to biomaterials

Popular Abstract in Swedish Det blir allt vanligare att man ersätter förlorade och skadade kroppsdelar med ett biomaterial (vanligtvis ett metall eller polymer implantat). Exempel på vanliga användningsområden är; suturer, kärl, hjärtklaffar, pacemakers, katetrar, ledproteser, fixationsskruvar för skelett och konstgjorda tänder samt kapslar för långsam frisättning av medicin. Trots det rutinmässigThe biological response to different implanted biomaterials vary. The relative importance of factors in the material and host for this variation are at present incompletely known. The variation in the cellular response to specific proteins and the rapid adsorption of proteins to surfaces exposed to biological environments has created the hypothesis that the cellular interactions with biomaterials

First 20 years with recombinant FVIIa (NovoSeven).

Summary. This review describes the background for the development of recombinant FVIIa (rFVIIa; NovoSeven) for use in haemophilic patients with inhibitors. The first proof of principle for using pharmacological doses of FVIIa as a haemostatic agent was obtained by producing small amounts of pure plasma-derived FVIIa, which showed encouraging effect in two patients with haemophilia A and inhibitors

Cervical or thoracic anastomosis after esophageal resection and gastric tube reconstruction - A prospective randomized triol comparing sutured neck anastomosis with stapled intrathorocic anastomosis

Objective: The purpose of the study was to compare in prospective randomized fashion a manually sutured esophagogastric anastomosis in the neck and a stapled in the chest after esophageal resection and gastric tube reconstruction. Summary Background Data: Despite the fact that all reconstructions after esophagectomy will result in a cervical or a thoracic anastomosis, controversy still exists as t

Konkurrensstrategier under hård konkurrens. Fallstudie på den svenska hemelektronikmarknaden.

Sammanfattning Uppsatsens titel: Konkurrensstrategier under hård konkurrens. Fallstudie på den svenska hemelektronikmarknaden. Seminariedatum: 31 maj 2012 Kurs: FEKN90 Magisteruppsats i Business Strategy, Företagsekonomi, 30 högskolepoäng (30 ECTS) Författare: Henrik Björkqvist och Connie Jakobsson Handledare: Tomas Hellström Nyckelord: Branschdynamik, hemelektronikmarknad, konkurrenssituati

Evaluation of deep geothermal exploration drillings in the crystalline basement of the Fennoscandian Shield Border Zone in south Sweden

The 3.1- and 3.7-km-deep FFC-1 and DGE-1 geothermal explorations wells drilled into the Precambrian crystalline basement on the southern margin of the Fennoscandian Shield are evaluated regarding experiences from drilling, geological conditions, and thermal properties. Both wells penetrate an approximately 2-km-thick succession of sedimentary strata before entering the crystalline basement, domina

Symptoms, problems and quality of life in patients newly diagnosed with oesophageal and gastric cancer - a comparative study of treatment strategy

BACKGROUND: Patients with oesophageal and gastric cancer have a low likelihood of being cured and suffer from a broad spectrum of symptoms and problems that negatively affect their quality-of-life (QOL). Although the majority (67-75%) of patients at the time of diagnosis suffer from an incurable disease, research has primarily focused on the pre- and postoperative phase among patients treated with

Transatlantic differences in the use and outcome of minimally invasive pancreatoduodenectomy : an international multi-registry analysis

BACKGROUND: Minimally invasive pancreatoduodenectomy (MIPD) has emerged as an alternative to open pancreatoduodenectomy (OPD). However, the extent of variation in the use and outcomes of MIPD in relation to OPD among countries is unclear as international studies using registry data are lacking. This study aimed to investigate the use, patient selection, and outcomes of MIPD and OPD in four transat

Postpartum perineal pain and its association with sub-classified second-degree tears and perineal trauma—A follow-up of a randomized controlled trial

Introduction: Postnatal perineal pain is prevalent following childbirth and can impact women both physically and emotionally. The aim of the study was to study the effect of collegial midwifery assistance on perineal pain and pain medication 1 month after birth and to investigate the associations between the type of tear and perineal pain, satisfaction with healing, and resumption of intercourse.

Plasma GDF-15 and PSP-D Predict the Development of Pulmonary Arterial Hypertension in Systemic Sclerosis

Patients with pulmonary arterial hypertension (PAH) experience long diagnostic delays, high functional class at diagnosis and poor prognosis. We aimed to study the differentiative and predictive value of 90 inflammatory and immunomodulatory related proteins in idiopathic and hereditary PAH (IPAH/HPAH) and systemic sclerosis-associated PAH (SSc-APAH). Cohort 1 comprised patients with SSc-APAH ( n =

Behavioral testing and litter effects in the rabbit

Background: Behavioral testing provides an essential approach in further developing our understanding of brain structure and function. The aim of our study was to outline a more expanded approach to cognition- and anxiety-related behavior in the rabbit. Methods: Twenty-one 70-day old rabbits (13 female, 8 male) were exposed to open field test, dark-light box test and object recognition testing wit

IMAGINE study protocol of a clinical trial : a multi-center, investigator-blinded, randomized, 36-month, parallel-group to compare the effectiveness of motivational interview in rehabilitation of older stroke survivors

BACKGROUND: Rehabilitation pathways are crucial to reduce stroke-related disability. Motivational Interviewing (MI), as a person-centered complex intervention, aimed to empower and motivate, and could be a resource to improve rehabilitation outcomes for older stroke survivors. The IMAGINE project aims to assess the impact of MI, as a complement to standard geriatric rehabilitation, on functional i

Bone Scan Index as an Imaging Biomarker in Metastatic Castration-resistant Prostate Cancer : A Multicentre Study Based on Patients Treated with Abiraterone Acetate (Zytiga) in Clinical Practice

Background Abiraterone acetate (AA) prolongs survival in metastatic castration-resistant prostate cancer (mCRPC) patients. To measure treatment response accurately in bone, quantitative methods are needed. The Bone Scan Index (BSI), a prognostic imaging biomarker, reflects the tumour burden in bone as a percentage of the total skeletal mass calculated from bone scintigraphy. Objective To evaluate

Mobile text messaging intervention to improve antiretroviral treatment adherence among adolescents living with HIV in Ethiopia

Adherence to antiretroviral therapy is a global problem among adolescents living with human immunodeficiency viruses (HIV), and it is associated with treatment failure and the development of viral resistance. One of the most significant barriers to treatment adherence among adolescents is forgetting to take drugs as prescribed. One of the key strategies recommended to improve this problem is the u

Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants

Background: Lumbar puncture (LP) is a common invasive procedure, most frequently performed to diagnose infection. Physicians perform LP in newborn infants with the help of an assistant using a strict aseptic technique; it is important to monitor the infant during all the steps of the procedure. Without adequate analgesia, LP can cause considerable pain and discomfort. As newborns have increased se

Expected features of the course leader in the rehabilitation healthcare professionals’ higher education : A qualitative study on students’ perspectives

Course leaders in rehabilitation healthcare professionals’ higher education face challenges stemming from multi-disciplinarity and the co-existence of different stakeholders. So far, the literature mainly attributed to course leaders’ managerial tasks, neglecting other fundamental transversal skills. Students represent an essential source of information for understanding the expected characteristi

Risk for periodontal disease in a Swedish adult population. Cross-sectional and longitudinal studies over two decades.

The overall aim of this thesis was to describe changes in the prevalence and severity of periodontal diseases and to identify risk factors for severe periodontal disease in adults living in Jönköping County, Sweden, by analysing the cross-sectional, epidemiological studies that had been carried out in the city of Jönköping in 1973, 1983, and 1993. Individuals were randomly selected from the follow

Endovascular repair of descending thoracic aortic aneurysms: an early experience with intermediate-term follow-up

PURPOSE: The purpose of this study was to report an initial experience with the endovascular repair of descending thoracic aortic aneurysm. Complications and intermediate-term morphologic changes were identified with the intent of altering patient selection and device design. METHODS: Endografts were placed into 25 patients at high-risk for conventional surgical repair over a 3(1/2)-year period. D

Structure, Morphology, and Catalytic Properties of CuOx/CeO2 Model Catalysts

Cerium dioxide, or ceria, is a chemically stable oxygen ion conducting material with a capacity to store and release oxygen, and is therefore extensively used in combustion catalysts. The Cu-Ce-O system has been identified as one of the most active catalysts for the combustion of carbon monoxide. To study the catalytic oxidation of CO, we have synthesised model CuOx/CeO2 cata

The influence of ageing on the salt-frost resistance of concrete

Popular Abstract in Swedish Jämte korrosionsangrepp är skador på grund av saltfrostangrepp den vanligaste skadetypen hos betongkonstruktioner som utsätts för miljöer med fukt, salt och frost. Exempel på sådana miljöer är marina miljöer och tösaltade vägmiljöer. Betongens saltfrostbeständighet bestäms till stor del av betongsammansättningen, främst av förhållandet mellan mängden vatten och cement oAbstract This thesis presents the results of an investigation of the influence of ageing on the salt-frost resistance of concrete. The ageing mechanisms investigated were hydration, drying and carbonation. Specimens of ‘micro’-concrete, either with OPC alone as the binder or with silica or slag as part of the binder, were freeze/thaw tested at different ages after casting. Prior to testing, the sp