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Background: Health professions education programs are tasked with designing curricula to effectively andefficiently equip their graduates with the required competences and life-long learning skills needed fortoday’s fast-paced, knowledge intensive society. Continuous monitoring and improving of educationalquality is essential to attain these goals. Quality assurance is multi-faceted and requires t
Amputation of a hand is a life-changing event, and the loss of motor and sensory functions leads to disability and has devastating effects on the individual. What is normally performed using two hands must be solved with only one, and the loss also affects body balance and body posture. In addition, amputation of a hand has psychological effects, and has an influence on social life, participation,
Recent studies have indicated a decline in sperm number in the western world during the past 50 years, sperm concentration changing from 113 to 66 millions per mL. Furthermore, significant geographical differences in male reproductive function have been observed. In Finland, the sperm concentration was found to be substantially higher than in Denmark. In parallel, the incidence of testicular cance
Cerebral accumulation of amyloid-β is thought to be the starting mechanism in Alzheimer's disease. Amyloid-β can be detected by analysis of cerebrospinal fluid amyloid-β42 or amyloid positron emission tomography, but it is unknown if any of the methods can identify an abnormal amyloid accumulation prior to the other. Our aim was to determine whether cerebrospinal fluid amyloid-β42 change before am
This paper presents in some detail findings and experiences gained from a new course entitled “Innovation Engineering” (IE). This course is offered in the Technology Management Programme (TM) at Lund University, Lund, Sweden. The incentive for developing the new course was the need for a more integrated and practical approach where technical, customer and application problems from reality confront
Studies of the long-lived anthropogenic radionuclides 99Tc, 237Np, 239Pu and 240Pu were performed in marine and terrestrial areas contaminated by different accidental and controlled releases of radioactive materials. The three main sources discussed in this thesis are nuclear weapons tests, nuclear reprocessing plants and the Chernobyl accident. Results are mainly based on measurements of environm
Enhanced biological phosphorus removal (EBPR) was studied in laboratory scale experiments as well as in a full scale EBPR process. The studies were focused on carbon source transformations, the use of nitrate as an electron acceptor and characterisation of the microflora. A continuous anaerobic/aerobic laboratory system was operated on synthetic wastewater with acetate as sole carbon source. An ef
Popular Abstract in Swedish Detta är en prospektiv longitudinell multicenterstudie som har haft som mål att utvärdera livskvaliteten (HRQL) hos patienter med cancer i huvudhalsregionen, vid diagnos, efter ett och fem år i relateration till tumörlokal, stadium, subsite, behand-ling, kön och ålder. Den första delen av studien, som varade i ett år, bestod av 357 patienter (medelålder 63 år; 72% män)The aim of this prospective longitudinal multicenter study was to evaluate the health-related quality of life (HRQL) in patients with head and neck cancer at diagnosis, after one and five years in relation to tumour location, stage, sub site, treatment modality, gender and age. The first part of the study, lasting for one year, consisted of 357 patients (mean age 63 years; 72% males) that were in
New methodologies based on supercritical fluid extraction (SFE) have been developed for the determination of fat-soluble vitamins in processed foods. The results obtained so far indicate that SFE is well suited to extraction of fat-soluble vitamins from food products, although validation work is required to establish accuracy and precision. The vitamins investigated were A, E and beta-carotene, an
Context. Open clusters are key tools to study the spatial distribution of abundances in the disk and their evolution with time. Aims. Using the first release of stellar parameters and abundances of the Gaia-ESO Survey, we analyse the chemical properties of stars in three old/intermediate-age open clusters, namely NGC 6705, NGC 4815, and Trumpler 20, which are all located in the inner part of the G
The timing of the ice margin retreat of the Late Glacial Patagonian Ice Sheet (PIS) in southern Patagonia has been the object of discussion for many years. In order to resolve questions about the complex response of the PIS to past climate change, any geological interpretation and data modelling need evaluation against an absolute chronology. The aim of this project is to investigate the applicabi
Lipid oxidation is a major problem in muscle foods, leading to a loss in quality and nutritional value. It occurs in raw meat but is usually more pronounced in cooked meat. Since the demands of consumers for ready-to-eat foods have increased, the control of off-flavour in cooked meat is an important industrial problem. One way of minimising the development of lipid oxidation is to optimise the act
This thesis is based on three different projects: 1) the epitaxial growth of nanowires using chemical beam epitaxy, 2) the study of electron transport through quantum dots and multiple quantum dots in nanowires at low temperature, and 3) the development of wrap gated nanowire field effect transistors. In the first part, a method of studying the diffusion of the source material on the substrate su
The aim of the present study was to enhance our understanding of vegetables as living organisms, interacting dynamically with the environment, and to explore the possible influence of metabolic changes on subsequent processing operations. Growing conditions, harvesting and handling in the packing house and storage conditions are key events leading to a defined “physiological status” of the vegetab
The moth, Spodoptera littoralis, was demonstrated to be a new model system for studying mechanisms underlying odour conditioning. In the experiments a restrained moth was trained to learn an association between a conditioned stimulus (CS) and an unconditioned stimulus (US). A proboscis extension reflex (PER) elicited by the conditioned odour was observed after learning. In paper I, an odour-sucros
This doctoral dissertation presents the development and digital hardware realization of cardiac event detectors. Implantable medical appliances, as the cardiac pacemaker, have progressed from a life sustaining device to a device that considerably improves life quality for all ages. The number of electronic devices and household appliances in everyday live has an ongoing exponential growth. The
Abstract in Uncoded languages Praegune kaitsejalatsite testimise standard (EN 344) kontrollib soojapidavuslikke omadusi vaid jalatsi ühes punktis, mõõtes temperatuuri muutust. Meetod, mis kasutab termilist jala mudelit, võimaldab mõõta jalatsi soojaisolatsiooni üheaegselt erinevates piirkondades ning ühtlasi ka jalatsi kui terviku soojaisolatsiooni. Selle uurimuse käigus arendati termilise jala mePresent standard on safety footwear (EN 344) checks the insulation only at one point in the shoes by means of measuring the temperature change. A method that uses thermal foot model allows to measure footwear insulation simultaneously at various locations and for whole footwear as well. In the present work the method of heated foot model was developed further. It is possible to simulate sweating a
How salamanders develop and regenerate with help from jumping genes Salamanders are famous for something most animals cannot do – they can regenerate lost body parts like limbs and tail, and even parts of their internal organs. They can reactivate genes used during early development and create cells that can proliferate and compensate for the loss. For decades, scientists have studied these anima
SUMMARY: Craniopharyngiomas (CPs) are rare brain epithelial tumours arising in the suprasellar region, infiltrating adjacent areas causing visual loss, panhypopituitarism, cognitive deficits and morbid obesity. Papillary CPs (PCPs) harbour in 94% BRAF mutation cases. Two patients with PCP and BRAF V600E mutations but with different tumour status were treated with BRAF and MEK inhibitors. Case I wa
