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Self-rated health in relation to age and gender: influence on mortality risk in the Malmö Preventive Project.

Aims: A study was undertaken to examine whether poor self-rated health (SRH) can independently predict all-cause mortality during 22-year follow-up in middle-aged men and women. Subjects and methods: Data are derived from a population-based study in Malmo¨ , Sweden. This included baseline laboratory testing and a self-administered questionnaire. The question on global SRH was answered by 15,590 me

Using Instagram in participatory visual methods - limitations of the platform

Interviews where photographs taken by the respondent are used in order to stimulate the conversation and to gain rich empirical material are increasingly employed by researchers. The ubiquitous use of mobile cameras and digital platforms such as Instagram has made it easier for the researcher as well as for the interviewees to take and share photographs. The limitations of participatory visual metInterviews where photographs taken by the respondent are used in order to stimulate the conversation and to gain rich empirical material are increasingly employed by researchers. The ubiquitous use of mobile cameras and digital platforms such as Instagram has made it easier for the researcher as well as for the interviewees to take and share photographs. The limitations of participatory visual met

Hypertension in Pregnancy Among Immigrant and Swedish Women : A Cohort Study of All Pregnant Women in Sweden

BACKGROUND: Little is known about risks of hypertensive disorders of pregnancy in both first-and second-generation immigrant women in Europe and other Western countries; such knowledge may help elucidate the influence of genetic versus social factors on such risks. We aimed to study both first-and second-generation immigrant women for the presence of all types of hypertension (preexisting hyperten

Copeptin, a Marker of Vasopressin, Predicts Vascular Dementia but not Alzheimer's Disease

Background: Copeptin is a reliable surrogate marker for the neurohypophyseal hormone vasopressin. Elevated plasma level of copeptin has been associated with cardiovascular and metabolic disease risk. Objective: To investigate the association between copeptin and risk of dementia. Methods: In all, 18,240 individuals from Malmö, Sweden, were examined between 2002 and 2006 (mean age 69.3 years, 69.8

Prevalence and intensity of pain after stroke: a population based study focusing on patients' perspectives.

OBJECTIVE: To determine prevalence and intensity of pain after stroke, focusing on patients' perspectives. METHODS: During a one year period, 416 first-ever stroke patients were included in the population based Lund Stroke Register. After 4 and 16 months (median), 297 patients (98% of survivors) were followed up. Worst pain intensity during the previous 48 hours was assessed on a visual analo

Predictors of work disability during the first 3 years after diagnosis in a national rheumatoid arthritis inception cohort.

OBJECTIVE: To identify predictors of sick leave and disability pension in patients with early rheumatoid arthritis (RA). METHODS: Individuals aged 19-59 years diagnosed with early RA (≤12 months symptom duration) were identified in the Swedish Rheumatology Quality Register (1999-2007; n=3029). We retrieved days of sick leave and disability pension from the Swedish Social Insurance Agency and basel

Effectiveness and survival-on-drug of certolizumab pegol in rheumatoid arthritis in clinical practice: results from the national Swedish register

Objectives: Evidence regarding the efficacy and effectiveness of certolizumab pegol (CZP) in rheumatoid arthritis (RA) patients who have failed to respond to treatment with a tumour necrosis factor inhibitor (TNFi) is limited. The aim of this study was to describe the effectiveness and survival-on-drug of CZP in a real-life setting, both in TNFi-naive patients and in patients who had previously fa

Kustprocesser i Arktis – med en fallstudie på Prins Karls Forland, Svalbard

Arktis står inför stora förändringar i samband med rådande klimat- och miljöförändringar, där de arktiska kusterna är utsatta. Förändringar i temperatur, havsnivå, stormar och havsisens utbredning är några av de faktorer som spelar in i hur kusterna och stränderna kan förändras. Syftet med studien är att först översiktligt se vilka kustmorfologiska förändringar som sker i Arktis idag och huruvida The Arctic is facing great changes due to current climate changes, where the Arctic coasts are especially vulnerable. Changes in temperature, mean sea level, storms and sea ice extent are some of the factors that shape how the coasts and beaches can be changed. The purpose of this study is firstly to examine what changes the Arctic coasts are experiencing today and whether they can be correlated t

De rättsliga möjligheterna att behandla insamlad hälsodata för vetenskapliga forskningsändamål

The more digitized our world becomes, the more information about us is documented in data. Health data provide the opportunity to research and promote health researchers to a greater extent foresee chronic diseases and the coming needs of the population. However, data is also valuable for companies as it tells them about the interests of their audience, enabling them to improve their customers'

Aspects of autoantibody epitopes in type 1 diabetes

Popular Abstract in Swedish I Sverige insjuknar två barn i autoimmun diabetes (typ 1 diabetes) varje dag. Typ 1 diabetes (T1D) är en kronisk autoimmun sjukdom som kan få livshotande konsekvenser vid utebliven behandling. Sverige har den högsta incidensen av T1D i hela världen efter Finland. Förutom att den delvis är ärftlig vet man inte vilken eller vilka faktorer som triggar sjukdomen. Sedan mittType 1 diabetes (T1D) is strongly associated with autoantibodies against insulin (IAA), glutamic acid decarboxylase 65 (GADA), insulinoma-associated protein 2 (IA-2A) and the most recently identified zinc T8 transporter (ZnT8A). Together or alone, they are important both to predict T1D and to classify diabetes at the time of clinical onset. The single nucleotide polymorphism (SNP) rs13266634 in th

Swedish snuff and incidence of cardiovascular disease. A population-based cohort study

Background: The relationship between smoking and an increased incidence of cardiovascular diseases is well known. Whether smokeless tobacco (snuff) is related to myocardial infarction (MI) or stroke is still controversial. Aim of this study was to explore whether snuff users have an increased incidence of MI or stroke. Methods: A total of 16 754 women and 10 473 men (aged 45-73 years), without his

Project Turnstone: Successful Collaboration and Collaboration Obstacles in Police, Border, and Coast Guard Cooperation

Projekt Turnstone är ett samverkansprojekt delvis finansierat av Europeiska kommissionen. Projektet är ett initiativ av Stockholmspolisens gränsbevakningsenhet. Samverkanspartners i projektet är Svenska Kustbevakningen, Region Nord öst; Helsingforspolisen; Gränsbevakningsväsendet, Finland; Polis och Gränsbevakningen i Estland; Statliga Gränsbevakningen, Lettiska republiken; och den Statliga GränssProject Turnstone is a collaborative project funded in part by the European Commission. The project is an initiative by the Stockholm Police. Collaborating partners in the project are the Swedish Coast Guard, Region Northeast; the Helsinki Police; the Gulf of Finland Coast Guard District; the Police and Border Guard Board in Estonia; the State Border Guard of the Republic of Latvia; and the State

Changes in body mass index following newly diagnosed type 2 diabetes and risk of cardiovascular mortality: A cohort study of 8486 primary-care patients

Aims. - Elevated body mass index (BMI) is associated with an increased risk of type 2 diabetes and cardiovascular disease (CVD). This study explored the association between BMI changes in the first 18 months of newly diagnosed type 2 diabetes and the risk of long-term CVD mortality. Methods. - A total of 8486 patients with newly diagnosed type 2 diabetes and no previous history of CVD or cancer we

Urban NO2 and NO pollution in relation to the North Atlantic Oscillation NAO

The North Atlantic Oscillation (NAO), a measure of the strength of the zonal wind across the North Atlantic Ocean, strongly influences weather conditions in NW Europe, e.g. temperature, precipitation and wind, especially during winter. It was hypothesised that elevated concentrations of nitrogen oxides in Gothenburg would be enhanced during negative NAO index (NAOI) conditions, representing more a

Best practice and needs for improvement in the chain of care for persons with dementia in Sweden: a qualitative study based on focus group interviews

Background: Persons with dementia receive health care and social services from a wide range of professional care providers during the disease trajectory, presenting risks of miscommunication, duplication and/or missed nursing interventions. Accordingly, the aim of this study was to investigate professional care providers' views on conditions for best practice in terms of collaboration and improvem

Cognitive Function in Young Men and the Later Risk of Fractures

Dementia has been associated with an increased risk of fractures. These associations may be explained by an impaired cognitive function, as well as comorbid illness and toxic reaction from drugs. To investigate whether cognitive function in young, healthy individuals already affects the risk of fractures, overall cognitive function scores were calculated from four cognitive tests accomplished duri

Giant prolactinomas in women

Objective: To characterise distinctive clinical features of giant prolactinomas in women. Design: A multicentre, retrospective case series and literature review. Methods: We collected data from 15 female patients with a pituitary tumour larger than 4 cm and prolactin levels above 1000 mu g/l and identified 19 similar cases from the literature; a gender-based comparison of the frequency and age dis

Late Quaternary ice sheet, lake and sea history of southwest Scandinavia - a synthesis

Based on a large number of new boreholes in northern Denmark, and on the existing data, a revised event-stratigraphy is presented for southwestern Scandinavia. Five significant Late Saalian to Late Weichselian glacial events, each separated by periods of interglacial or interstadial marine or glaciolacustrine conditions, are identified in northern Denmark. The first glacial event is attributed to

Different responses of myocardial and cerebral blood flow to cord occlusion in exteriorized fetal sheep

Type and duration of fetal asphyxial insult affect the distribution of blood flow to the heart and brain. The purpose of this study was to describe dynamic and quantitative changes in regional myocardial and cerebral blood flow (CBF) during fetal asphyxia induced by total occlusion of the umbilical cord. Eleven exteriorized fetal sheep were subjected to total umbilical cord occlusion and five feta

Asthma quality of life during 1 year of treatment with budesonide with or without formoterol

The Formoterol and Corticosteroids Establishing Therapy (FACET) study has provided the first opportunity to examine the long-term effects of inhaled steroids and long-acting beta2-agonists on asthma-specific quality of life. The objectives of the present study were to: evaluate the effects of long-term (1 yr) formoterol and increasing doses of budesonide on asthma quality of life; 2) to determine