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Speed control is the most important aspect of promoting road safety world-wide. The question is how are speeds developing? The European Transport Safety Council concludes: There is little progress on reducing speeds in Europe. Similar conclusions can be drawn from the US and Australia. Attitude surveys show that people’s answers are not very consistent and represent statements without any strong b
This article considers the ways in which geo-political and legal concerns materialised in debates over self-determination in the years following decolonisation, and how they impacted on its’ possibilities, objectives and conception. During this period, self-determination was not, as some scholars have argued, a declining norm, but one central to the competing visions of reinventing international l
The description of ultrafast nonadiabatic chemical dynamics during molecular photo-transformations remains challenging because electronic and nuclear configurations impact each other and cannot be treated independently. Here we gain experimental insights, beyond the Born-Oppenheimer approximation, into the light-induced spin-state trapping dynamics of the prototypical [Fe(bpy) 3 ] 2+ compound by t
Introduction: Ischemic spinal cord injury (SCI) is a serious complication of complex aortic repair. Prophylactic cerebrospinal fluid (CSF) drainage, used to decrease lumbar cerebrospinal fluid (CSF) pressure, enables monitoring of CSF biomarkers that may aid in detecting impending SCI. We hypothesized that biomarkers, previously evaluated in traumatic SCI and brain injury, would be altered in CSF
In addition to their natural substrates GDP and GTP, the bacterial translational GTPases initiation factor (IF) 2 and elongation factor G (EF-G) interact with the alarmone molecule guanosine tetraphosphate (ppGpp), which leads to GTPase inhibition. We have used isothermal titration calorimetry to determine the affinities of ppGpp for IF2 and EF-G at a temperature interval of 5-25 °C. We find that
Background: Mental health problems are prevalent among adolescents with severe obesity, but long-term mental health outcomes after adolescent bariatric surgery are not well known. We aimed to assess mental health outcomes over 5 years of follow-up after Roux-en-Y gastric bypass surgery in adolescents who participated in the Adolescent Morbid Obesity Surgery (AMOS) study. Methods: This was a non-ra
BACKGROUND: The Chronic Kidney Disease in Children Study (CKiD) equation for children and the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation for adults are recommended serum creatinine (SCr)-based calculations for estimating glomerular filtration rate (GFR). However, these equations, as well as their combination, have limitations, notably the problem of implausible changes in
The Northeast region of Brazil is one of the most susceptible parts of the country to the effects of climate variability leading to severe droughts or extreme floods. Indeed, drought is a major issue due to a large semiarid area that covers 53% of the region, which determines the main climate characteristics of this region. On the other hand, extreme floods have caused widespread damage in river b
Laterally grown InxGa1-xAs nanowires (NWs) are promising candidates for radio frequency and quantum computing applications, which, however, can require atomic scale surface and interface control. This is challenging to obtain, not least due to ambient air exposure between fabrication steps, which induces surface oxidation. The geometric and electronic surface structures of InxGa1-xAs NWs and conta
A search for the supersymmetric partners of quarks and gluons (squarks and gluinos) in final states containing jets and missing transverse momentum, but no electrons or muons, is presented. The data used in this search were recorded by the ATLAS experiment in proton-proton collisions at a centre-of-mass energy of s = 13 TeV during Run 2 of the Large Hadron Collider, corresponding to an integrated
Pain, use of painkillers and alcohol are highly prevalent in the general population. Aims of the study were to describe differences in pain, alcohol consumption and use of painkillers among two 60 year old birth cohorts stratified by gender. Participants were recruited from the Skåne centre of The Swedish National study on Aging and Care, a multicentre, prospective, longitudinal study. The sample
The effects of endogenous and exogenous cyclic AMP on the synthesis of pancreatic lipase, colipase, and amylase were studied. Pancreatic lobules were prepared and incubated with forskolin, dibutyryl cyclic AMP (dbcAMP), and dibutyryl cyclic GMP (dbcGMP), respectively, in the presence of “S-cysteine”. The individual pancreatic enzymes were isolated by polyacrylamide gel electrophoresis, and the inc
In the last century, starch present in foods was considered to be completely digested. However, during the 1980s, studies on starch digestion started to show that besides digestible starch, which could be rapidly ors lowly hydrolysed, there was a variable fraction that resisted hydrolysis by digestive enzymes. That fraction was named resistant starch (RS )and it encompasses those forms of starch t
The present work explores challenges when assessing organ dose and effective dose concerning image-guided treatments. During these treatments considerable x-ray imaging is employed using technically advanced angiographic x-ray equipment. Thus, the radiation dose to organs and the related radiation risk are relatively difficult to assess. This has implications on the optimisation process, in which
Denna rapport beskriver ett urval av 1184 vuxna svenskar (medelvärdesålder = 48.72 år, standardavvikelse = 12.17; 75.5 % kvinnor, 1.3 % annan eller ej angiven könsidentitet) som upplever olika typer av fysisk smärta. Data samlades in via en internetenkät, som under 2017 utannonserades via olika patientföreningar, sociala medier och vårdcentraler. I bortsett från att de flesta av deltagarna identif
Dense urban morphologies further amplify extreme climate events due to the urban heat island phenomenon, rendering cities more vulnerable to extreme climate events. Here we develop a modelling framework using multi-scale climate and energy system models to assess the compound impact of future climate variations and urban densification on renewable energy integration for 18 European cities. We obse
IMPORTANCE: The clinical utility of stress cardiovascular magnetic resonance imaging (CMR) in stable chest pain is still debated, and the low-risk period for adverse cardiovascular (CV) events after a negative test result is unknown.OBJECTIVE: To provide contemporary quantitative data synthesis of the diagnostic accuracy and prognostic value of stress CMR in stable chest pain.DATA SOURCES: PubMed
Arktis står inför stora förändringar i samband med rådande klimat- och miljöförändringar, där de arktiska kusterna är utsatta. Förändringar i temperatur, havsnivå, stormar och havsisens utbredning är några av de faktorer som spelar in i hur kusterna och stränderna kan förändras. Syftet med studien är att först översiktligt se vilka kustmorfologiska förändringar som sker i Arktis idag och huruvida The Arctic is facing great changes due to current climate changes, where the Arctic coasts are especially vulnerable. Changes in temperature, mean sea level, storms and sea ice extent are some of the factors that shape how the coasts and beaches can be changed. The purpose of this study is firstly to examine what changes the Arctic coasts are experiencing today and whether they can be correlated t
Support groups for children and young people whose parents abuse drugs or alcohol are a relatively new phenomenon. A major purpose of these support groups is for the participating children to understand that they are not alone in their situation. In these support groups there are also social workers whose job is to guide the children and help them understand their situation through different theme
