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The Gaia-ESO Survey: Abundance ratios in the inner-disk open clusters Trumpler 20, NGC 4815, NGC 6705

Context. Open clusters are key tools to study the spatial distribution of abundances in the disk and their evolution with time. Aims. Using the first release of stellar parameters and abundances of the Gaia-ESO Survey, we analyse the chemical properties of stars in three old/intermediate-age open clusters, namely NGC 6705, NGC 4815, and Trumpler 20, which are all located in the inner part of the G

First Encounters : Young People’s Perceptions of Criminal Justice

For young people, a first encounter with criminal justice can have lasting effects. While perceptions of equitable treatment can generate feelings of belongingness and acceptance, treatment perceived as unfair or prejudicial can generate experiences of dissonance and exclusion. However, little research has examined young people’s appraisals of justice system encounters. The purpose of the study wa

Visuo-Locomotive Update in the Wild The Role of (Un)Familiarity in Choice of Navigation Strategy, and its Application in Computational Spatial Design

We study active human visuo-locomotive experience in everyday navigation from the viewpoints of environmental familiarity, embodied reorientation, and (sensorimotor) spatial update. Following a naturalistic, in situ, embodied multimodal behaviour analysis method, we conclude that familiar users rely on environmental cues as a navigation-aid and exhibit proactive decision-making, whereas unfamiliar

Role of transposable elements in regulating gene expression in developing Pleurodeles waltl embryos

How salamanders develop and regenerate with help from jumping genes Salamanders are famous for something most animals cannot do – they can regenerate lost body parts like limbs and tail, and even parts of their internal organs. They can reactivate genes used during early development and create cells that can proliferate and compensate for the loss. For decades, scientists have studied these anima

Treatment with BRAF/MEK : inhibitors in mutant BRAF V600E papillary craniopharyngioma

SUMMARY: Craniopharyngiomas (CPs) are rare brain epithelial tumours arising in the suprasellar region, infiltrating adjacent areas causing visual loss, panhypopituitarism, cognitive deficits and morbid obesity. Papillary CPs (PCPs) harbour in 94% BRAF mutation cases. Two patients with PCP and BRAF V600E mutations but with different tumour status were treated with BRAF and MEK inhibitors. Case I wa

No Place like Home? Postdeployment Reintegration Challenges Facing South African Peacekeepers

This study focuses on soldiers returning from peacekeeping missions and the challenges they experience adapting to the home environment in the postdeployment phase. The article focuses on South African peacekeepers returning from missions in Darfur/Sudan, the Democratic Republic of Congo, and Burundi. Interviews with 50 South African peacekeepers on the challenges they face in terms of their homec

Effect of Shortening the Scan Duration on Quantitative Accuracy of [18F]Flortaucipir Studies

Purpose: Dynamic positron emission tomography (PET) protocols allow for accurate quantification of [18F]flortaucipir-specific binding. However, dynamic acquisitions can be challenging given the long required scan duration of 130 min. The current study assessed the effect of shorter scan protocols for [18F]flortaucipir on its quantitative accuracy. Procedures: Two study cohorts with Alzheimer’s dis

Risks of depression, anxiety, and suicide in partners of men with prostate cancer : a national cohort study

Background: A diagnosis of prostate cancer (PC) may cause psychosocial distress not only in a man but also in his intimate partner. However, long-term risks of depression, anxiety, or suicide in partners of men with PC are largely unknown. Methods: A national cohort study was conducted of 121 530 partners of men diagnosed with PC during 1998-2017 and 1 093 304 population-based controls in Sweden.

To continue or not to continue? Antipsychotic medication maintenance versus dose-reduction/discontinuation in first episode psychosis : HAMLETT, a pragmatic multicenter single-blind randomized controlled trial

Background: Antipsychotic medication is effective for symptomatic treatment in schizophrenia-spectrum disorders. After symptom remission, continuation of antipsychotic treatment is associated with lower relapse rates and lower symptom severity compared to dose reduction/discontinuation. Therefore, most guidelines recommend continuation of treatment with antipsychotic medication for at least 1 year

Deep learning-based auditory attention decoding in listeners with hearing impairment

This study develops a deep learning method for fast auditory attention decoding (AAD) using electroencephalography (EEG) from listeners with hearing impairment. It addresses three classification tasks: differentiating noise from speech-in-noise, classifying the direction of attended speech (left vs. right) and identifying the activation status of hearing aid noise reduction (NR) algorithms (OFF vs

Early Toxicity in Childhood Acute Lymphoblastic Leukemia : A Comparison of NOPHO ALL2008 and ALLTogether Protocols in Sweden

Background: The European ALLTogether protocol for childhood acute lymphoblastic leukemia, initiated in Sweden 2019, introduced earlier asparaginase during induction, dexamethasone instead of prednisone for all patients, and omitted anthracyclines from low-risk induction to reduce treatment-related toxicity. Consolidation-1 was based on the Induction 1B-phase developed by the BFM-group, replacing m

Updated automated PROMISE assessment : Treatment response evaluation based on PSMA PET/CT.

Background: PSMA PETs can track treatment response in patients with prostate cancer. Recent integration of the RECIP framework with PROMISE v2 allows quantitative assessment of PSMA PETs. While useful for assessing differentially responding lesions, manual measurement and tracking is cumbersome and PSA reliance can be misleading. We evaluated an automated AI-enabled platform, aPROMISE, for longitu

How can cooperation between rehabilitation professionals in rehabilitation planning be improved? A qualitative study from the employer's perspective.

Research shows that there are often problems with cooperation between rehabilitation professionals within vocational rehabilitation. The aim of this study was to describe employers' experiences of how cooperation between different rehabilitation professionals can be improved in a vocational rehabilitation planning process. Ten employers who had sent their employees to vocational rehabilitation at

Abrupt decreases in infectivity of SARS-CoV-2 in aerosols

A respiratory virus emitted in an aerosol particle will experience a tough journey with many obstacles before finding a new host where it can cause an infection (Fig. 1). By every second, its chances to replicate decrease due to removal by building ventilation, deposition on surfaces, or loss in infectivity. Thus, the transport of infectious viruses from the exhaled breath of one person to the inh

How have Supplemental Instruction-Peer Assisted Study Sessions (SI-PASS) programmes adapted during the COVID-19 pandemic? Case Studies from four Higher Education Institutes in Ireland, Norway, the UK and Sweden

In this paper we look at the adaption of SI-PASS programmes during the COVID-19 pandemic drawing from four Higher Education Institutions (HEIs) as case studies: The National University of Ireland (NUI) Galway in Ireland, Nord University in Norway, Lund University in Sweden and the University of Manchester in the UK. The paper also focuses on the role of SI-PASS in student engagement in an extraord

Functional Priorities in LCA and Design for Environment

Aim, Scope and BackgroundThe interest in environmental questions has increased enormously during the last decade. Environmental protection has become an issue of strategic importance within the manufacturing industry and many companies are now working in the field of Design for Environment (DFE). The main purpose of DFE is to create products and services for achieving a sustainable society. Design

Dwell time delays for commuter trains : An analysis of the influence of passengers on dwell time delays

The thesis presented here delves into why dwell time delays for commuter trains occur, with a specific focus on the impact of boarding and alighting passengers. The overarching aim is to develop knowledge of how time delays arise to identify and describe potential ways in which dwell time delays can be reduced. In addition to this, a secondary aim is to identify how dwell times can be studied on a