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Polymer gel dosimetry - Using MRI-readout, simplified relatively non-toxic mixing procedure tested on FLASH

Background: One of the polymer gel dosimeters available today is the N-isopropylamide (NIPAM) polymer gel dosimeter which has a less toxic monomer compared to other polymer gels and the advantage of being able to be manufactured under normal oxygen levels. Polymer gel dosimeters in general are advantageous independent dosimeters to use for verification of new radiation treatment techniques due to

Modeling normal tissue complication probability from repetitive computed tomography scans during fractionated high-dose-rate brachytherapy and external beam radiotherapy of the uterine cervix

PURPOSE: To calculate the normal tissue complication probability (NTCP) of late radiation effects on the rectum and bladder from repetitive CT scans during fractionated high-dose-rate brachytherapy (HDRB) and external beam radiotherapy (EBRT) of the uterine cervix and compare the NTCP with the clinical frequency of late effects.METHODS AND MATERIALS: Fourteen patients with cancer of the uterine ce

Beta-Glycosidases from Hyperthermophiles as Biocatalysts

The thesis concerns glycosyl transfer with use of b-glycosidases, most of them from hyperthermophilic organisms. Both optimisation of the reaction conditions and protein engineering in terms of site-directed mutagenesis were used to improve b-glycosidase-catalysed reactions. The first part of the work deals with conversion of lactose into valuable products such as galacto-oligosaccharides (GOS) an

Incidence and outcome of surgery for adult hydrocephalus patients in Sweden

Object: To present population-based and age related incidence of surgery and clinical outcome for adult patients operated for hydrocephalus, registered in the Swedish Hydrocephalus Quality Registry (SHQR). Methods: All patients registered in SHQR during 2004–2011 were included. Data on age, gender, type of hydrocephalus and type of surgery were extracted as well as three months outcome for patient

Prevalence and predictive importance of anemia in Swedish nursing home residents - A longitudinal study

Background: Anemia is common in elderly people and especially in nursing home residents. Few studies have been performed on the consequences of anemia in a nursing home population. This study explored the prevalence of anemia in nursing homes in Sweden, including risk factors and mortality associated with anemia or hemoglobin (Hb) decline. Methods: Three hundred ninety patients from 12 nursing hom

Oligomerization of human and bacterial frataxin : Structural and functional studies

Iron is a one of the critical elements in our life, being the most common element on earth, forming most of the inner and outer earth’s core. In our bodies iron is required in small amounts for biological processes to be performed. It is recommended to eat food containing iron to avoid common health problems such as anemia. A slight increase or decrease in iron levels above or below normal in liviFriedreich’s ataxia (FRDA) is an autosomal recessive neurodegenerative disease caused by defeciency in frataxin, a highly conserved protein central to iron homeostasis in mirochondria. The function of frataxin is related to its capability to bind, store and deliver iron to different biochemical process such as iron-sulfur cluster assembly and heme biosynthesis. Most FRDA pateints have extended GAA

Exchange of CO2 in Arctic tundra : Impacts of meteorological variations and biological disturbance

An improvement in our process-based understanding of carbon (C) exchange in the Arctic and its climate sensitivity is critically needed for understanding the response of tundra ecosystems to a changing climate. In this context, we analysed the net ecosystem exchange (NEE) of CO2 in West Greenland tundra (64°N) across eight snow-free periods in 8 consecutive years, and characterized the key process

Extraction and chromatography of bioactive compounds in complex samples using supercritical CO2 technology

Medical doctors and nutritional specialists recommend to eat healthy foods including fruits and vegetables. Cosmetic experts also recommend to use cosmetic products obtained from natural products. The reason behind this is that natural products from plants contain chemical compounds which can promote health and protect our bodies from several diseases. These chemical compounds are called bioactiveBioactive compounds found in plants have been of interest to man since ancient times. These compounds have the ability to modulate the metabolic processes in our bodies, which suggests that they may promote better health. Bioactive compounds vary in their chemical structure, polarity, stability and biological activity. This diversity makes the study of bioactive compounds challenging from the pers

Potassium Disturbances and Risk of Ventricular Fibrillation Among Patients With ST-Segment-Elevation Myocardial Infarction

Background Potassium disturbances per se increase the risk of ventricular fibrillation (VF). Whether potassium disturbances in the acute phase of ST-segment-elevation myocardial infarction (STEMI) are associated with VF before primary percutaneous coronary intervention (PPCI) is uncertain. Methods and Results All consecutive STEMI patients were identified in the Eastern Danish Heart Registry from

Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk : An IMI DIRECT study

Background: Dietary advice remains the cornerstone of prevention and management of type 2 diabetes (T2D). However, understanding the efficacy of dietary interventions is confounded by the challenges inherent in assessing free living diet. Here we profiled dietary metabolites to investigate glycaemic deterioration and cardiometabolic risk in people at risk of or living with T2D. Methods: We analyse

Ischemic brain damage in rats following cardiac arrest using a long-term recovery model

A model is described in which transient complete cerebral ischemia is induced in rats by intracardiac injection of potassium chloride. The animals were intubated and mechanically ventilated with a nitrous oxide/oxygen (70:30) mixture. Cardiac arrest was achieved following a brief period of ventricular fibrillation. After 5-6 min, the circulation was restored by cardiopulmonary resuscitation and pa

High and rising burden of hip and knee osteoarthritis in the Nordic region, 1990-2015

Background and purpose - Osteoarthritis (OA) imposes a substantial burden on individuals and societies. We report on the burden of knee and hip OA in the Nordic region. Patients and methods - We used the findings from the 2015 Global Burden of Diseases Study to explore prevalence, years lived with disability (YLDs), and disability-adjusted life-years (DALYs) of OA in the 6 Nordic countries during

Diesel Exhaust Exposure Assessment Among Tunnel Construction Workers—Correlations Between Nitrogen Dioxide, Respirable Elemental Carbon, and Particle Number

Objectives: Occupational exposure to diesel exhaust is common due the widespread use of dieselpowered combustion engines. Diesel exhaust is chemically complex and consists of thousands of compounds present as gases and particulate matter. Both nitrogen dioxide (NO2) and elemental carbon(EC) have been used as markers for diesel exhaust exposure. Currently EC is regarded as the best surrogate of die

WHAT ARE THE CHARACTERISTICS OF AIRBORNE PARTICLES THAT WE ARE EXPOSED TO? Focus on Indoor Environments and Emissions from Biomass Fired District Heating

Ambient fine particulate matter PM2.5 (particles with a diameter smaller than 2.5 μm) has been associated with cardiovascular and respiratory morbidity and mortality. It has been shown that biomass burning for heat production purposes can generate large amounts of fine particles. Thus characteristics of particle emissions from biofuel combustion may be important in the assessment of health effects

Electron Transport in Quantum Dots Defined in Low-Dimensional Semiconductor Structures

Popular Abstract in Swedish I denna avhandling studeras ledningsförmågan hos nanometer-stora kvantprickar tillverkade i halvledarmaterial. Halvledare är material vars ledningsförmåga ligger någonstans mellan ledare (metaller) och isolatorer. I halvledare kan ledningsförmågan ändras med elektriska fält, vilket har möjliggjort utvecklandet av halvledartransistorn. Utvecklandet av halvledartransistorThis thesis focuses on electron transport in single and double quantum dots defined in low-dimensional, narrow-band-gap III-V semiconductor materials. Fabrication schemes are presented for defining single and double quantum dots in lateral InGaAs/InP heterostructures, either by a combination of etching and local gating or solely by local top gating. The quantum dots are here electrostatically conf

Lunds-universitets-magasin-6-2012

Liten omslagsrubrik 3 Liten omslagsrubrik 2 Liten omslagsrubrik 1 Stor omslags- Lunds universitets magasin | nr 6 | 2012 versaL Liten omsLagsrubrik 2 LUM nr 6 | 2012 LUM nr 6 | 2012 3 – Uppåkra är fantastiskt! Vi har funnit så mycket bara i det översta jordlagret – ett bronshänge, en yxa och en skrapa av flinta, och massor av djurben. Jag vill gärna komma tillbaka nästa sommar. I love it here! Ste

https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-6-2012.pdf - 2026-05-27

Work Report 2021 Updated

The Centre for East and South-East Asian Studies work report 2021 The Centre for East and South- East Asian Studies Work Report 2021 CENTRE FOR EAST AND SOUTH-EAST ASIAN STUDIES 2 CENTRE FOR EAST AND SOUTH-EAST ASIAN STUDIES WORK REPORT 2021 Work report 2021 for the Centre for East and Southeast Asian Studies OVERVIEW The pandemic has continued to affecte the Centre in different ways, most obvious

https://www.ace.lu.se/sites/ace.lu.se/files/2022-02/Work%20Report%202021%20updated.pdf - 2026-05-27