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Prediction of Hospitalizations in Systemic Lupus Erythematosus Using the Systemic Lupus International Collaborating Clinics Frailty Index

Objective: The Systemic Lupus International Collaborating Clinics (SLICC) frailty index (FI) predicts mortality and damage accrual in systemic lupus erythematosus (SLE), but its association with hospitalizations has not been described. Our objective was to estimate the association of baseline SLICC-FI values with future hospitalizations in the SLICC inception cohort. Methods: Baseline SLICC-FI sco

Postmenopausal overweight and breast cancer risk; results from the KARMA cohort

Purpose: To study the risk of incident breast cancer and subtype-specific breast cancer in relation to excess body weight in a contemporary Swedish prospective cohort study, The Karolinska Mammography Project for Risk Prediction of Breast Cancer, KARMA. Methods: A total of 35,412 postmenopausal women attending mammography and included in the KARMA study provided baseline data on body mass index (B

Optical diagnostics of misfire in partially premixed combustion under low load conditions

To clarify the misfire mechanism is important for stabilizing combustion in partially premixed combustion (PPC) under low load. Fuel-tracer planar laser-induced fluorescence (PLIF), formaldehyde PLIF, flame and OH* natural luminosity imaging were utilized to qualify the local equivalence ratio, low-temperature reaction and the high-temperature flame features in an optical engine. Results show that

Alcohol use disorder and non-fatal suicide attempt : findings from a Swedish National Cohort Study

Background and Aims: Alcohol use disorder (AUD) is associated with increased risk of non-fatal suicide attempt. We aimed to measure the strength and mechanistic nature of the association between AUD and increased suicide attempt and determine any causal pathways and/or shared risk factors. Design: We used Cox proportional hazards models in population-level and co-relative analyses to evaluate the

The Gaia -ESO survey: Mixing processes in low-mass stars traced by lithium abundance in cluster and field stars

Aims. We aim to constrain the mixing processes in low-mass stars by investigating the behaviour of the Li surface abundance after the main sequence. We take advantage of the data from the sixth internal data release of Gaia-ESO, IDR6, and from the Gaia Early Data Release 3, EDR3s. Methods. We selected a sample of main-sequence, sub-giant, and giant stars in which the Li abundance is measured by th

Doing 'Good' and Gender Equal Family : Employing Nannies and Au Pairs in Sweden

Delegated, but still intensive: Quality time and parenting in upper-middle class families in Sweden During the last decade, Swedish families have started to employ nannies and au pairs to an extent previously never experienced. Political initiatives such as tax deductions for household services, together with global trends of ‘care chains’, have created a private market for care services, which ha

Geographies of fear – visitors’ perceptions of safety in urban destinations

Countering fear and promoting experiences of security and safety among visitors are key issues in creating socially sustainable urban destinations. Security branding is a growing place branding paradigm through which to enhance experiences and perceptions of safety in cities, nations and regions (Coaffee and Van Ham, 2008; Coaffee and Rogers, 2008; Avraham and Ketter, 2008). This paper discusses h

General User Surveys in Quality Development – Discovering Best Practices in Library Services

In 2015, LIBER commissioned the “Working group on Research and Education”. The goal was to collect best practices in library support to both education and research, in part by examining user survey data. As a first step the group started a European LibQUAL consortium, which was evaluated in 2016. As a second step, a survey sent to all 301 European LIBER university libraries asking questions pertai

PREVALENCE OF BIOPSY-PROVEN GIANT CELL ARTERITIS IN SOUTHERN SWEDEN

Background: Few previous studies have examined the prevalence of giant cell arteritis (GCA). The main objective of this study is to investigate the prevalence of temporal artery positive GCA (TAB+GCA) in southern Sweden.Methods: The study area is the region of Skåne in southern Sweden with a population of 1,3 million inhabitants (36% aged ⩾50 years). To be included in the study, patient should ful

Resistance–recovery trade-off of soil microbial communities under altered rain regimes : An experimental test across European agroecosystems

With the increased occurrence of climate extremes, there is an urgent need to better understand how management strategies affect the capacity of the soil microbial community to maintain its ecosystem functions (e.g. nutrient cycling). To address this issue, intact monoliths were extracted from conventional and ecological managed grasslands in three countries across Europe and exposed under common

Delimiting a saline water zone in Quaternary fluvial–alluvial deposits using transient electromagnetic : a case study in Punata, Bolivia

The semiarid Punata alluvial fan is located in the central part of Bolivia. The main activity of this region is the extensive agriculture, and groundwater is the main water supply. Local villagers who use groundwater reported that in some places groundwater has a salty taste. In order to investigate the origin of this problem, several TEM soundings were performed in the study area, and they were c

Bridging gaps in everyday life - a free-listing approach to explore the variety of activities performed by physiotherapists in specialized palliative care

BACKGROUND: A growing body of studies indicate benefits of physiotherapy for patients in palliative care, for symptom relief and wellbeing. Though physiotherapists are increasingly acknowledged as important members of palliative care teams, they are still an underutilized source and not fully recognized. The aim of this study was to explore the variety of activities described by physiotherapists i

On Reduction of Nitrogen Oxides in Heavy-Duty Engines : with NOx Model Feedback, PPC and SNCR

European emission legislation has in recent years put a strict limit on NOx emissionsfrom heavy-duty truck engines. EGR and selective catalytic reduction are the two mostcommon technologies applied in a modern heavy-duty diesel engine to fulfill the legislation.The scope of this thesis is to explore other ways of reducing NOx emissions emittedby a heavy-duty engine. Several technology options are

Development of the thermotolerant methylotrophic yeast hansenula polymorpha as efficient ethanol producer

Until recently, the methylotrophic yeasts, including Hansenula polymorpha, have not been considered as a potential producer of biofuels, particularly, ethanol from lignocellulosics. However it is already known that the thermotolerant methylotrophic yeast H. polymorpha is capable to ferment xylose, glucose and cellobiose, the main sugars of lignocellulosic hydrolysates, under elevated temperature.

Serotonin release from mesencephalic raphe neurons grafted to the 5,7-dihydroxytryptamine-lesioned rat hippocampus : Effects of behavioral activation and stress

Transplants of fetal midbrain raphe neurons into the adult brain have been shown to promote recovery of complex behavioral deficits in several experimental models, but the mechanisms underlying these effects are only partially understood. In the present study, we have used a well-characterized model system to ascertain whether midbrain raphe graft can display behaviorally relevant changes in trans

Long-term Safety and Efficacy of Reslizumab in Patients with Eosinophilic Asthma

Background In placebo-controlled trials, reslizumab, an anti-IL-5 monoclonal antibody, significantly reduced asthma exacerbations and improved lung function and asthma control in patients with eosinophilic asthma. Objective This open-label extension study evaluated safety and efficacy of reslizumab for up to 24 months. Methods After participation in 1 of 3 placebo-controlled, phase III trials in m

Evaluating Flood Risk Reduction by Urban Blue-Green Infrastructure Using Insurance Data

One of many important features of blue-green infrastructure is the ability to lower flood risks by detention of stormwater. This ability of flood risk reduction has for the first time been evaluated with empirical data in this study. In 2014, Malmö, Sweden, was hit with extreme precipitation corresponding to a return period of 50–200 years that led to severe pluvial flooding. This and other large

Prevalence and incidence of non-gout crystal arthropathy in southern Sweden

Objective: To estimate the prevalence and incidence of non-gout crystal arthropathy in relation to socioeconomic factors in southern Sweden. Methods: All patients (age ≥ 18 years) with at least one visit to a physician with the diagnosis of interest in the Skåne region (population of 1.3 million) in 1998-2014 were identified. Non-gout crystal arthropathy (ICD-10 codes M11.0-M11.9) was subclassifie

Midlife risk factor exposure and incidence of cardiac arrest depending on cardiac or non-cardiac origin

Objective: Little is known about midlife risk factors of future cardiac arrest. Our objective was to evaluate cardiovascular risk factors in midlife in relation to the risk of cardiac arrest (CA) of cardiac and non-cardiac origin later in life. Methods: We cross-matched individuals of the population based Malmö Diet and Cancer study (n = 30,447) with the local CA registry of the city of Malmö. Bas