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This study aimed to explore the value of synchrotron-based phase-contrast microcomputed tomography (micro-CT) in pulmonary vascular pathobiology. The microanatomy of the lung is complex with intricate branching patterns. Tissue sections are therefore difficult to interpret. Recruited intrapulmonary bronchopulmonary anastomoses (IBAs) have been described in several forms of pulmonary hypertension,

Human milk fat is a concentrated source of energy and provides essential and long chain polyunsaturated fatty acids. According to previous experiments, human milk fat is partially lost during continuous enteral nutrition. However, these experiments were done over relatively short infusion times, and a complete profile of the lost fatty acids was never measured. Whether this loss happens considerin

Background: A major part of medical pathology in internal medicine is associated with chronic alcoholism. The aim of the current study was to investigate whether screening for Alcohol Use Disorders (AUD) can be improved through determination of direct ethanol metabolites compared to traditional biological state markers, the Alcohol Use Disorders Identification Test (AUDIT) and additional self-repo

Objective: To evaluate the effects of eccentric isokinetic training on knee range of motion (ROM) of healthy subjects. Methods: The knee extensor and flexor isokinetic peak torques and ROM of flexion/extension and varus/valgus knee movements during gait of 18 healthy men (21.7 +/- 2.2 years; 1.73 +/- 0.10m; 68.7 +/- 9.4kg; body mass index: 22.6 +/- 2 kg/m(2)) were analyzed, before and after six we

Recent studies indicate a severely reduced coronary flow reserve (CFR) in neonates with congenital heart disease. The significance of these studies remains debatable, as the ability of the anatomically normal neonatal heart to increase coronary flow is currently unknown. This study was designed to establish normal values for CFR in newborns after administration of adenosine [pharmacologic CFR (pCF

Total gastrectomy or resection of the acid-producing part of the stomach (fundectomy) in the rat induced a marked and rapid reduction in bone wet weight, ash weight, and density (expressed as ash weight in mg/mm3 bone). Bone volumes were also affected but not as much. The radius, sternum, tibia, and femur were studied. Three weeks after gastrectomy the bone ash weight was reduced by almost 30% and

PURPOSE: To investigate acute and long-term changes in hormonal and inflammatory biomarkers in nonambulant children with cerebral palsy in response to dynamic standing exercise.METHODS: Fourteen children with severe cerebral palsy were recruited. Anthropometrics and body composition measures were obtained. Physical activity levels before the study were assessed using hip-worn accelerometry. All ch

Audiobooks have in recent years become widely popular. The format accordingly impacts how many contemporary readers use and experience literature. The article examines this tendency, departing from Rita Felski’s theoretical conceptualizations of uses of literature (Felski 2008). Felski represents a new attention within literary studies toward the ways in which so-called lay readers use, experience

Chronic kidney disease of non-traditional origin (CKDnt) and acute kidney injury (AKI) often affect heat-stressed Mesoamerican manual workers. Inflammation occurs concurrently with AKI in this population, but its role remains unknown. To explore links between inflammation and kidney injury in heat stress, we compared levels of inflammation-related proteins in cutters with and without increasing se

For a better understanding of the effects of regional groundwater management for different land-use types on nitrogen content in groundwater, we investigated the Miyakonojo River Basin in south of Japan where the Nitrate Directive Plan has been in practice since 2004. For this purpose, we used nitrogen concentrations from 420 wells between 2000 and 2017 together with 8 different land-use categoriz

Increasing inequality in many societies highlights the importance of paying attention to differences in mentalhealth between the economically disadvantaged adolescents and the non-disadvantaged adolescents. Also im-portant is to understand how changing inequality in society over time influences adolescents’mental health atthe population- and individual-level. The current study examined to what ext

Extreme climate events and nonsustainable land use are important drivers altering the functioning of European ecosystems, resulting in loss of the services provided. Yet a consensus method for regular continental scale assessment of ecosystem condition in relation to land degradation (LD) is still lacking. Here, we propose a new remote sensing-based approach allowing for improved, repeated assessm

Transport of people and freight on-road have a big impact on the total energy use in the world. The majority of these transports is propelled with diesel engines and the reason is simply that the diesel engine is better than the gasoline engine due to lower fuel consumption. But the cost of this is the increase in dangerous nitrogen oxides (NOx). Around 10 000 people dies everyyear due to emission

The objective in this research has been to predict the current and future moisture and temperature distribution in a concrete reactor containment, RC. The overall objective in this project was to create a model to be able to predict the moisture and temperature distribution in the concrete wall of the RC of a Pressurized Water Reactor, PWR. In addition, one objective was to design a model to simul

The purpose of this study is to let a group of addicted mothers who live separated from their children voice their thoughts and experiences through in-depth interviews made in the early 90's. From a perspective of experience of life we look at their living conditions, their everyday life, their experiences of pregnancy, their life with the children, and their life after the separation. What does i

Background: Orthostatic hypercoagulability is proposed as a mechanism promoting cardiovascular and thromboembolic events after awakening and during prolonged orthostasis. We evaluated early changes in coagulation biomarkers induced by tilt testing among patients investigated for suspected syncope, aiming to test the hypothesis that orthostatic challenge evokes procoagulatory changes to a different

Background: Pancreatic cancer is a devastating disease with a dismal prognosis. Despite profound medical advances in systemic therapies for other types of aggressive tumours during recent years, a diagnosis of pancreatic cancer is still often synonymous with a fatal outcome. The term periampullary cancer includes pancreatic cancer and applies to the group of tumours found in proximity to the ampul

Chest pain is one of the most common complaints at the emergency department (ED), and it is commonly the perceived likelihood of acute coronary syndrome (ACS) that drives management. Guidelines from the European Society of Cardiology (ESC) recommend the use of a 0-/1-h high-sensitivity cardiac troponin T (hs-cTnT) protocol to rule out or in ACS, but this is mostly based on observational studies. T

The variabilities in rainfall and temperature in a catchment affect water availability and sustainability. This study assessed the variabilities in rainfall and temperature (1981–2015) and river flow (1998–2015) in the Sipi sub-catchment on annual and seasonal scales. Observed daily rainfall and temperature data for Buginyanya and Kapchorwa weather stations were obtained from the Uganda National M

The reliable detection of neutrons in a harsh gamma-ray environment is an important aspect of establishing non-destructive methods for the characterization of spent nuclear fuel. In this study, we present results from extended in-situ monitoring of detector systems consisting of commercially available components: EJ-426, a 6Li-enriched solid-state scintillator material sensitive to thermal neutron