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We present an interim archaeological report on the ship- wreck of the Danish-Norwegian flagship Gribshunden. Built in 1485, extensively employed by King Hans as his floating castle, and ultimately lost in June 1495 en route to Kalmar, the ship carried people and material selected to further the political goal of re-unifying the Nordic region. Three field campaigns led by Lund University and Blekin
“Water is life”. During the past decade this phrase has been used repeatedly to emphasize the importance of a number of issues surrounding water services provision including, supply, distribution, governance and political will. This research seeks to investigate the Nairobi City Water and Sewerage Company (NCWSC), a water utility in Kenya, which faces the monumental task of providing water and san
Corruption is indisputably an immense obstacle for many developing countries in their endeavor to prosper economically. Zambia, a peaceful, politically stable democracy is still facing many of the problems connected with corruption. Corruption has so far mostly been measured on a state-level, but in our thesis we narrow the field of investigation down to the ministry-level. We use questionnaires t
EndoS from Streptococcus pyogenes efficiently hydrolyzes the functionally important and conserved N-linked glycan of IgG in human blood. Repeated i.v. administration of EndoS in rabbits completely hydrolyzes the glycans of the whole IgG pool, despite the generation of anti-EndoS antibodies. EndoS administration had no apparent effects on the health of the animals. EndoS hydrolysis of the IgG glyca
Angiogenesis is a hallmark of cancer and is now a validated therapeutic target in the clinical setting. Despite the initial success, anti-angiogenic compounds impinging on the vascular endothelial growth factor (VEGF) pathway display limited survival benefits in patients and resistance often develops due to activation of alternative pathways. Thus, finding and validating new targets is highly warr
Group B Streptococcus (GBS) is a leading cause of invasive bacterial infections in human newborns. A key GBS virulence factor is its capsular polysaccharide (CPS), displaying terminal sialic acid (Sia) residues which block deposition and activation of complement on the bacterial surface. We recently demonstrated that GBS Sia can bind human CD33-related Sia-recognizing immunoglobulin (Ig) superfami
Regular prophylactic treatment with factor VIII (FVIII) and factor IX (FIX) concentrates in hemophilia A and B, respectively, is introduced in early infancy and has resulted in dramatic improvement of the conditions. Recombinant FVIII and FIX concentrates have been available for > 25 years and have been modified and refined through the years; however, unfortunately frequent intravenous administrat
Lymphocytes from human peripheral blood were separated by Countercurrent distribution (CCD) in a charged aqueous two-phase system composed of Dextran T 500 and polyethylene glycol 6000. Maximal responses to the T-cell mitogens phytohemagglutinin and concanavalin A were detected in a part of the distribution corresponding to the area where the highest percentage of E rosetting cells were seen. Anti
We have characterized 2 distinct mechanisms through which infectious agents may promote platelet adhesion and thrombus formation in flowing blood, thus contributing to the progression of disease. In one case, the process initiates when the integrin alpha(IIb)beta(3) mediates platelet arrest onto immobilized bacterial constituents that have bound plasma fibrinogen. If blood contains antibodies agai
Protein ADP-ribosylation is a reversible post-translational modification that regulates important cellular functions. The identification of modified proteins has proven challenging and has mainly been achieved via enrichment methodologies. Random mutagenesis was used here to develop an engineered Af1521 ADP-ribose binding macro domain protein with 1000-fold increased affinity towards ADP-ribose. T
Soils play a critical role in the carbon (C) cycle by regulating the atmospheric carbon dioxide (CO2) levels, and correspondingly the Earth’s climate. However, there are still countless questions of how biological and geochemical soil processes affect the C cycle. To be able to predict future implications on the Earth’s climate, we need to understand these processes. Globally, soils store more C tIron oxide nanoparticles are involved in several important biogeochemical processes. The interfaces between aqueous solutions and iron oxide nanoparticle surfaces are found everywhere in nature, and the chemical and microbial processes occurring at these complex interfaces control e.g. nutrient and contaminant availability and transport. Recently, it has been shown that certain ectomycorrhizal (EC
Psykologiska rapporter från Lund Volym 8, Nr. 1, 2018 Hen. Bakgrund, attityder och användande Emma A. Bäck Anna Lindqvist Marie Gustafsson Sendén Psykologiska rapporter från Lund Redaktör: Magnus Lindgren ISSN: 1404-8124 Innehåll Kort om författarna Sammanfattning Introduktion Historik Hur används hen? Språk och jämställdhet Konsekvenser av genus i språket Reformer för genusrättvist språk Enkätstu
https://www.psy.lu.se/sites/psy.lu.se/files/plr_1801.pdf - 2026-07-25
Background: A significant proportion of patients with asthma have persistent symptoms despite treatment with inhaled glucocorticosteroids. Objective: We hypothesized that in these patients, the alveolar parenchyma is subjected to mast cell-associated alterations. Methods: Bronchial and transbronchial biopsies from healthy controls (n = 8), patients with allergic rhinitis (n = 8), and patients with
SYFTE Avfallshandbok Dokumentets namn Gäller för Dnr Sida Avfallshandbok Lunds universitet V 2016-370 2 (67) Utarbetad av Godkänd av Utgåva Datum Miljösamordare Miljöchef 1 2016-02-10 INNEHÅLL 1. Inledning............................................................................................................................ 4 1.1 Om denna avfallshandbok ........................................
https://www.geologi.lu.se/sites/geologi.lu.se/files/avfallshandbok_-lu_ac.pdf - 2026-07-25
SYFTE Avfallshandbok Dokumentets namn Gäller för Dnr Sida Avfallshandbok Lunds universitet V 2016-370 2 (67) Utarbetad av Miljösamordare Godkänd av Miljöchef Utgåva 1 1 Datum 2016-02-10 INNEHÅLL 1. Inledning ............................................................................................................................ 4 1.1 Om denna avfallshandbok .....................................
https://www.geologi.lu.se/sites/geologi.lu.se/files/avfallshandbok_-lu.pdf - 2026-07-25
