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Presented here is an engineered protein domain, based on Protein A, that displays a calcium-dependent binding to antibodies. This protein, ZCa, is shown to efficiently function as an affinity ligand for mild purification of antibodies through elution with ethylenediaminetetraacetic acid. Antibodies are commonly used tools in the area of biological sciences and as therapeutics, and the most commonl
Streptococcus pyogenes infects over 700 million people worldwide annually. Immune evasion strategies employed by the bacteria include binding of the complement inhibitors, C4b-binding protein (C4BP) and Factor H in a human-specific manner. We recently showed that human IgG increased C4BP binding to the bacterial surface, which promoted streptococcal immune evasion and increased mortality in mice.
Barbaricum 070302 Den andliga makten Entré Reception The Spiritual Beliefs Vapenoffer War Sacrifies Soldaten The Soldier Den Världsliga makten The Worldly Dominion Eldstaden The Fireplace Uppåkratemplet The Uppåkra Temple Bägaren och skålen The Beaker and the Bowl Guldgubbarna The Gold-Figure Foils Den nakna gudinnan The Naked Goddess Porten The Gate Information Information Keramiken The Ceramics
https://www.historiskamuseet.lu.se/sites/historiskamuseet.lu.se/files/2023-09/Barbaricumboken%20pdf%202007.pdf - 2026-07-22
Pyranose 2-oxidase (P20x) has several proposed biotechnological applications such as a bio-component in biofuel cells or for carbohydrate transformations. To improve some of the catalytic properties of P20x from Trametes multicolor, we selected a semi-rational approach of enzyme engineering, saturation mutagenesis of active-site residues and subsequent screening of mutant libraries for improved ac
The development of EU labour and social law has been described as a pendulum in the sense of focus shifting between economic interests, such as competitiveness for industry, and social interests, such as improving working and living conditions. This view is to a large extent based on the presumption that those interests are contrasting and pursuing one of them would necessarily exclude the promoti
Despite systematic screening and improved treatment strategies, the prognosis remains worse in patients with connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH) compared to patients with idiopathic/hereditary pulmonary arterial hypertension (IPAH). We aimed to investigate differences in clinical characteristics, outcome and performance of the European Society of Cardiolo
Examensarbete_Johan_Svensson Department of Mechanical Engineering Solid Mechanics ISRN LUTFD2/TFHF-07/5125-SE(1-69) Utveckling av termisk analys med avseende p̊a val av analyserade tidpunkter gällande HT-turbinen i RM12 Master’s Dissertation by Johan Svensson Supervisors Magnus Andersson, Volvo Aero Corporation, Sweden Per Pettersson, Volvo Aero Corporation, Sweden Håkan Hallberg, Div. of Solid
https://www.solid.lth.se/fileadmin/hallfasthetslara/utbildning/examensarbete/TFHF5125.pdf - 2026-07-20
The present article describes data from pilot studies with the Swedish versions of the Mindful Attention Awareness Scale (MAAS) and the Kentucky Inventory of Mindfulness Skills (KIMS). The MAAS and two of the KIMS scales, Act with Awareness and Accept without Judgment, were found to correlate in the predicted direction with measures of well-being and emotional distress. The KIMS scales Observe and
Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease encompassing a wide range of symptoms that can emanate from pathology in virtually any organ system. Severe SLE includes involvement of the central nervous system and kidneys. One of the hallmarks of the disease is a multitude of autoantibodies, indicating a breakdown in self tolerance. The corresponding antigens have been fou
In everyday conversations, we frequently give an example. Yet this is seldom accompanied by any reflection on what is going on when we do so. This report tries to contribute such a reflection. It shows how examples may be marked and used in a particular discourse: oral discourse on others. The empirical material is a transcribed focus group interview with a group of Swedish students, engaged in di
