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The purpose of this essay is to examine how users experience ‘dark pattern marketing’ from an ethical standpoint, and if it makes a difference if the users are aware of the phenomenon. ‘Dark pattern marketing’ is - in short terms - a marketing approach that applies a user interface that has been carefully crafted to trick and manipulate users into doing things they did not intend to do, or discour
The background for this master thesis is the stricter emission control requirement in heavyduty diesel engines at the same time as the demands for improved diesel engine efficiency are getting stronger. One approach to meet these demands is to increase the fuel injector pressure. A higher fuel injector pressure makes the fuel spray more finely dispersed into the cylinder and a better combustion is
Epithelial ovarian carcinoma is a gynecological cancer with the highest death incidence worldwide. It is treated with surgery and chemotherapeutic drugs: platinum or taxane. However, around 80% of patients have disease progression into more aggressive and chemoresistant cancer. Mitochondria are structures inside both normal and cancer cells which are central to the cell´s metabolism by supplying e
OBJECTIVE: To investigate the possible role of FCGR2A 519A>G and FCGR3A 559A>C functional polymorphisms in the genetic predisposition to susceptibility to systemic sclerosis (SSc) or clinical phenotype. METHODS: A total of 1566 patients with SSc and 2271 geographically matched controls were included in our study. We analyzed the genotype and allele frequencies of the FCGR2A 519A>G and FCGR3A 559A>
In a previous study we presented data indicating that the expanded population of CD4(-)CD8(-) (DN) alphabeta T cells in TCRalpha-chain-transgenic mice was partially if not entirely derived from gammadelta T cell lineage cells. The development of both gammadelta T cells and DN alphabeta T cells is poorly understood; therefore, we thought it would be important to identify the immediate precursors of
Immunoglobulin G (IgG) glycosylation modulates antibody activity and represents a major source of heterogeneity within antibody preparations. Depending on their glycosylation pattern, individual IgG glycovariants present in recombinant antibody preparations may trigger effects ranging from enhanced pro-inflammatory activity to increased anti-inflammatory activity. In contrast, reduction of IgG gly
Measurements are presented of inclusive charm and beauty cross sections in e(+)p collisions at HERA for values of photon virtuality 12 <= Q(2) = 60 GeV2 and of the Bjorken scaling variable 0.0002 <= x <= 0.005. The fractions of events containing charm and beauty quarks are determined using a method based on the impact parameter, in the transverse plane, of tracks to the primary vertex, as measured
Protein kinase C (PKC) plays a prominent role in immune signaling, and the paradigms for isoform selective signaling are beginning to be elucidated. Real-time microscopy was combined with molecular and biochemical approaches to demonstrate a role for PKC-epsilon in Fcgamma receptor (FcgammaR)-dependent phagocytosis. RAW 264.7 macrophages were transfected with GFP-conjugated PKC isoforms, and GFP m
Current hemophilia B treatment guidelines recommend routine prophylaxis with factor IX (FIX) replacement products, tailored to maintain plasma activity at levels that will prevent bleeds. However, plasma FIX activity may not be the primary determinant or best indicator of hemostatic efficacy due to its extravascular distribution. FIX replacement therapy has evolved to include extended half-life (E
Packaging is one of the logistics areas where there often is potential and even a demand for improvements. An increase in environmental awareness among the population in the European Union (EU) has generated a demand for changes in packaging, which has led to stricter rules and regulations. Knowledge about what regulations are present and what may be expected in the future is crucial in the formin
Mängden kostnadsfria kartor som finns tillgängliga genom nedladdningstjänster på internet kommer enligt trenden i samhället att öka. I och med det kommer även antalet nedladdningstjänster öka. Att fler kan tillgå kostnadsfria kartor kommer troligtvis leda till nya produkter och tjänster som kan öka effektiviteten för både privat och offentlig sektor. Nya tjänster kan även leda till bättre service,There are currently numerous web services that provide the user with the opportunity to download geodata. These services are often different regarding what type of data they provide and the way they distribute the data. Another aspect that differs between these services is if the download of geodata is free of charge (open) or subject to a fee. There is currently a trend in the society striving to
In order to suggest improvements for the logistics of STARKA, we felt that we had to analyze all the activities which were related to STARKA's logistic processes. Our primary analysis consisted of a rough but comprehensive description of different functions in the company, and the relationship between them. This was performed by following a typical order through the company to see which functi
Abstract Sweden has experienced a dramatic change from being a belligerent greatpower in the 17th and 18th centuries to becoming a peaceful small nation in the 19th and 20th centuries. The country has not been involved in war for over 180 years. Modern Sweden has established more or less peaceful relations with other countries. This thesis focuses on the 19th century as beeing an important period
