Filetype
Background: Free and total human kallikrein 2 (hK2) might improve the discrimination between prostate cancer and benign prostatic hyperplasia. Concentrations of hK2 are 100-fold lower than concentrations of prostate-specific antigen (PSA); therefore, an hK2 assay must have a low detection limit and good specificity. Methods: PSA- and hK2-specific monoclonal antibodies were used in solid-phase, two
OBJECTIVE: To evaluate newly developed equations predicting relative glomerular filtration rate(GFR) in adult Swedish Caucasians and to compare with the Modification of Diet in Renal Disease(MDRD) and Mayo Clinic equations using enzymatic and zero-calibrated plasma creatinine assays. MATERIAL AND METHODS: GFR was measured with iohexol clearance adjusted to 1.73 m(2). One population sample (n=436/L
Inferential models have long been used to determine pollutant dry deposition to ecosystems from measurements of air concentrations and as part of national and regional atmospheric chemistry and transport models, and yet models still suffer very large uncertainties. An inferential network of 55 sites throughout Europe for atmospheric reactive nitrogen (N-r) was established in 2007, providing ambien
We present an evaluation of a nested high-resolution Goddard Earth Observing System (GEOS)-Chem chemistry transport model simulation of tropospheric chemistry over tropical South America. The model has been constrained with two isoprene emission inventories: (1) the canopy-scale Model of Emissions of Gases and Aerosols from Nature (MEGAN) and (2) a leaf-scale algorithm coupled to the Lund-Potsdam-
Background. Poor ultrafiltration is associated with worse outcomes in peritoneal dialysis (PD) patients. This might in part reflect problems associated with salt and water excess. Increasing the diffusive component of peritoneal sodium removal using low-sodium PD fluids might have beneficial effects on blood pressure (BP), thirst and fluid status that could translate into clinical benefits. Method
Objectives Osteoarthritis (OA) is the most common form of arthritis with a clear genetic component. To identify novel loci associated with hip OA we performed a meta-analysis of genome-wide association studies (GWAS) on European subjects. Methods We performed a two-stage meta-analysis on more than 78 000 participants. In stage 1, we synthesised data from eight GWAS whereas data from 10 centres wer
Brain-machine interfaces (BMIs) provide a uni- or bidirectional communication link between the central nervous system and the outside world. This link facilitates the studying of neuronal mechanisms underlying behavior as well as the treatment of neurological disease. Wired BMIs are limited in the sense that they restrict the mobility of the subject and they increase the risks for post-surgical co
Popular Abstract in Swedish Förlossning efter kejsarsnitt Kejsarsnitt utgör för närvarande cirka 17% av alla förlossningar i Sverige. En konsekvens av detta är att allt fler kvinnor kommer till specialistmödravården för rådgivning om vilket förlossningssätt som är säkrast vid förlossningen efter ett kejsarsnitt. Två möjligheter finns: planerad vaginal förlossning eller planerat kejsarsnitt. När maBirth after caesarean section (CS) is an issue of growing importance. As a consequence of increasing CS rates, more women having experienced a prior CS will need counselling about preferred second delivery mode. There are two choices: elective repeat caesarean section (ERCS) or trial of labour (TOL). It is well known, that a TOL ending in an emergency CS carries the largest risks for mother and ch
OBJECTIVE--To explore associations between exposure to asbestos cement dust and radiographic findings in lung parenchyma and pleura. METHODS--Radiographs from 174 blue collar workers and 29 white collar workers from an asbestos cement plant formed one part of the study. Progression of small opacities was further studied in those 124 blue collar workers, for whom two radiographs taken after the end
Background: Chronic Pseudomonas aeruginosa (PA) infection causes increased morbidity and mortality in cystic fibrosis (CF). This study aimed to answer the following questions: Does the prevalence of chronic infection with PA differ between the CF centres in Scandinavia? Which differences exist concerning segregation and treatment of PA? Methods: 989 patients (86%) from all eight CF-centres in Scan
A recent statement from the European-Society-for-Sexual-Medicine has highlighted the limitations of using the rat model for nerve-sparing prostatectomy. The use of young rats with no comorbidities and the early evaluation of the erectile function (EF) are deemed a source of bias. Our aim was to evaluate the long-term consequences in EF of bilateral nerve cavernous crush- injury (BNCI) in type 1 di
Scarce water resources present a major hindrance to ensuring food security. Crop water productivity (WP), embraced as one of the Sustainable Development Goals (SDGs), is playing an integral role in the performance-based evaluation of agricultural systems and securing sustainable food production. This study aims at developing a cloud-based model within the Google Earth Engine (GEE) based on Landsat
In the current work, in order to model a free electron solvated in water, we have implemented a method to represent the molecular charge distribution as a set of Slater-type functions within the framework of a QM/MM method called QMSTAT. Also, it has been introduced in this method a new approach to calculate the intermolecular induction energy in the presence of very strong electric fields. Unlike
The accurate interpretation of Si isotope signatures in natural systems requires knowledge of the equilibrium isotope fractionation between Si-bearing solids and the dominant Si-bearing aqueous species. Aqueous silicon speciation is dominated by silicic acid (H4SiO4 o) in most natural aqueous fluids at pH < 8.5, but forms H3SiO4 −, H2SiO4 2−, and polymeric Si species in more alkaline fluids. In th
Background: In 2014 the Swedish government assigned to The Public Health Agency of Sweden to conduct studies to evaluate optimal use of existing antibiotic agents. The aim is to optimize drug use and dosing regimens to improve the clinical efficacy. The present study was selected following a structured prioritizing process by independent experts. Methods: This phase IV study is a randomized, open-
OBJECTIVES: Bleeding complications associated with acute type A aortic dissection (aTAAD) are a well-known clinical problem. Here, we evaluated predictors of massive bleeding related to aTAAD and associated surgery and assessed the impact of massive bleeding on complications and survival. METHODS: This retrospective study of 256 patients used Blood Conservation Using Antifibrinolytics in a Randomi
The effects of various glycosaminoglycans (GAGs) on the growth rate of normal fibroblasts and a fibrosarcoma cell line (HT 1080) were examined. Cells were grown in 96-well microplates in the absence or presence of serum mitogens, epidermal (EGF), platelet-derived (PDGF), acidic fibroblast (aFGF), or basic fibroblast growth factor (bFGF). Cell number was measured by using crystal violet to stain ce
Om inte statusen på Sveriges byggnadsbestånd förbättras kommer miljömålet ”God bebyggd miljö” inte kunna uppfyllas. Då miljömålet beaktar många aspekter måste ett holistiskt synsätt gälla vid genomförandet av åtgärder i byggnadsbeståndet. För att kunna göra detta måste en dialog föras kring viktiga aspekter på byggnadens samtliga områden mellan inblandade parter. Om en parameter ändras riskerar deCurrently, Sweden faces a major environmental challenge. If the status of its building stock doesn’t improve, the environmental goal “En god bebyggd miljö” will not be reached. Since this goal considers a wide range of aspects it’s essential that the same holistic approach is considered when implementing measures on the building stock. For this to be possible, an extensive dialogue needs to be hel
Heterogena katalysatorer för användning i bränslecellssystem har undersökts baserat på aktiv fas och tillverkningsmetoder för granulat- och monolitkatalysatorer. Katalysatorerna tillverkades genom att använda θ – aluminiumoxid som bärare, dopad med lantan och cerium, där den aktiva fasen bestod av ädelmetall X och nickel i varierande halter. Analys gjordes genom att låta en blandning av vattenångaHeterogeneous catalysts to be used in a pre-reformer for fuel cell systems have been investigated based on active phase composition and catalyst preparation methods for granulate and monolithic catalysts. The catalysts were manufactured using θ – aluminum oxide as carrier, promoted with lanthanum and cerium, with active phases consisting of noble metal X and nickel in various concentrations. Analy
