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OBJECTIVES: Opioid-free anesthesia (OFA) is a promising alternative to traditional opioid-based anesthesia. Research indicates that OFA reduces postoperative opioid consumption and related adverse effects while maintaining effective pain control and patient safety. Despite these benefits, clinical adoption of OFA remains limited, possible due to gaps in evidence. To bridge this knowledge gap, a we
In this forum, seven scholars discuss Oliver P. Richmond’s The Grand Design: The Evolution of the International Peace Architecture, published in 2022. The editors, Gëzim Visoka and Annika Björkdahl, contextualise the book’s contribution within the broader intellectual framework of Richmond’s thoughts and writings on peace in the context of International Relations. Roland Bleiker examines the book’
Aggrecan (ACAN) is localized in the intervertebral disc (IVD) in unique compartment-specific patterns where it contributes to the tissue structure and mechanical function together with collagens. The extracellular matrix (ECM) of the IVD undergoes degenerative changes during aging, misuse or trauma, which inevitably alter the biochemical and biomechanical properties of the tissue. A deeper underst
AbstractSevere perineal trauma (SPT) is a serious complication following vaginal birth. To reduce its incidence rate, various preventive strategies have been implemented in Swedish obstetric units. Collegial midwifery assistance (CMA), involving an additional midwife being present during the active second stage of labour, is a clinical practice that was evaluated in the Oneplus trial, which proved
In the 1920s and 30s, a criminal investigation followed by a trial against a group of allegedly homosexual men was launched in Gothenburg, Sweden. Almost a century later, Swedish artist Conny Karlsson Lundgren engages with these events in a multifaceted two-part installation and performative work that borrows the title from the investigation, The Gothenburg Affair (Göteborgsaffären). In this artic
The flavour-tagging algorithms developed by the ATLAS Collaboration and used to analyse its dataset of s=13 TeV pp collisions from Run 2 of the Large Hadron Collider are presented. These new tagging algorithms are based on recurrent and deep neural networks, and their performance is evaluated in simulated collision events. These developments yield considerable improvements over previous jet-flavou
Quantitative in-cylinder measurements of soot volume fraction in a single-cylinder HSDI Diesel engine, based on a VOLVO D5, has been carried out using the laser-induced incandescence (LII) technique using laser excitation at 1064 nm and an ICCD camera with prompt gate detection. Quantitative data was obtained by relating the LII signal response from the engine to that from a calibration flame. The
Despite evidence that cesarean section rates above 10 percent at the population level do not reduce maternal or neonatal mortality, global rates continue to rise and are projected to reach 30 percent by 2030. The factors behind this increase are complex and vary across contexts, emphasizing the need for a local understanding in order to design and implement effective interventions to curb overuse.
Syftet med denna avhandling är att undersöka användningen av naturrättsligt språkbruk i de danska agrarreformerna, cirka 1750-1800. Detta görs genom en social kontextualisering som fokuserar på de sprickor som fanns i det danska samhället före och under reformperioden. Jag hävdar att dessa huvudsakligen utgjordes av interna materiella skillnader inom den danska jordägande eliten, inklusive deras oPopular science description The agrarian reforms of the 18th century were some of the most momentous historical events in Danish history. In the span of 30 years, half of all peasants went from living in a state of serfdom to owning and cultivating their own plots of land, free from the onerous ties of manorial dependence that they had toiled under for hundreds of years. In this pioneering dissert
Episodic memory allows the flexible retrieval of commonalities and idiosyncrasies of overlapping life events. For example, seeing a woman in the city with your colleague's daughter may form an integrated memory representation involving the woman and your colleague. However, you may also keep a specific representation of the city event to talk with your colleague about the circumstances of having m
BACKGROUND: The advent of PD-1/PD-L1 inhibitors has revolutionized lung cancer treatment, necessitating accurate PD-L1 immunohistochemical (IHC) assessment. While standardized for formalin-fixed paraffin-embedded (FFPE) histological samples, PD-L1 testing on cytology remains challenging. This review aims to address the complexities of PD-L1 IHC in cytology, focusing on validation guidelines, quali
The EU’s recent regulatory approach in the digital sphere promises to introduce greater consideration for fundamental rights. However, this does not apply to all fundamental rights and their holders equally. With particular focus on the freedom to conduct a business, this article will be exploring the restrictions imposed on certain undertakings—so-called gatekeepers—operating in the Digital Singl
Skolämnet Idrott och hälsa (IDH) har ett brett innehåll eftersom det inkluderar både idrottsaspekter och hälsoaspekter. Tidigare studier har visat att idrott-delen dominerar på flera sätt, delvis på grund av ett vagt och icke-specifikt ämnesspråk i ämnesplaner, kursplaner och läromedel (Lundin & Schenker 2021, 2022; Lundin m.fl. 2021, 2023). Detta resulterar i att hälsoaspekterna av ämnet inteThe school subject Physical Education and Health (PEH) has a wide scope with respect to its content, combining the aspects ‘sports’ and ‘health’. Previous studies have shown that for the Swedish school subject PEH, sports dominate the content of the subject in several aspects, as a result of, for instance, a vague and unspecific subject specific literacy used in the curricula and course books (Lun
The aim of the thesis is to analyse the transfer pricing rules in the VAT system, namely Articles 72 and 80 of the Recast VAT directive. The thesis specifically aims to investigate the application of the open market value to improperly valued transactions between related parties, what the open market value in the VAT system is and how it is determined. The second chapter of the thesis presents an
The purpose of this thesis is to investigate how accurate multiple valuations are in relation to the DCF. Furthermore, the accuracy of equity and entity multiples will be compared. Finally, we will try to determine the factors underlying the valuation errors. Our results suggest similar performance from the multiples approach in relation to the DCF model in estimating corporate value with eight
The purpose of this essay was to analyze the collapse of democracy in the Weimar Republic. This was done by analyzing some of the most turbulent crises in its history like the communists attempt to take power in 1919, the kapp-putsch of 1920, hyperinflation 1923 and the economic depression 1929-1933. The method that I used in this essay is called methodological individualism. It was an analytical
