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Aims Oral anticoagulation with vitamin K antagonists (VKAs) for stroke prevention in atrial fibrillation (AF) is effective but has significant limitations. AZD0837, a new oral anticoagulant, is a prodrug converted to a selective and reversible direct thrombin inhibitor (AR-H067637). We report from a Phase II randomized, dose-guiding study (NCT00684307) to assess safety, tolerability, pharmacokinet
The effect of side chain length of pi-conjugated poly(9,9-dialkylfluorene)s has been studied in semi-dilute (10 mg/mL) toluene solutions using small-angle neutron scattering (SANS) and H-1 and H-2 NMR spectroscopies. Under these conditions, SANS data indicate that poly(9,9-dinonylfluorene) and poly(9,9-dioctylfluorene) are dissolved down to the molecule level and appear as elongated one-dimensiona
Measurements of soil matric potential (Psi) are needed in many soil science applications. In the present study, a small matric potential sensor having a length of 30 mm and a diameter of 9.6 mm was developed. The sensor consists of two coils made of lacquer-coated copper wires embedded in gypsum. The dielectric constant of the gypsum (K-gypsum) was measured with time domain reflectometry (TDR). Th
Objectives To develop normal reference ranges for cervical volume and vascular indices using three-dimensional (3D) power Doppler ultrasonograpby from 17 to 41 gestational weeks. Methods This was a cross-sectional study of 352 nulliparous and 291 parous women who delivered at term and underwent transvaginal 3D power Doppler ultrasound examination of the cervix once at 17 to 41 weeks' gestation. We
In the swedish social legislation we have a measure called "contact-family". Contact families are ordinary people who will do a contribution to appointed children. The social welfare committe commissions the contact families. In Sweden "contact" family is the most used measure in the prevent social work welfare with children in riskzone. I have done an investigation in a commun
This paper explores whether rising gang-related crime in Sweden affects investment decisions in the Swedish stock market, particularly examining if its impact varies between Swedish and foreign investors. The study focuses exclusively on public owners, leaving out non-public entities like small investors. Utilizing data from 2004 to 2023, which includes the 30 most traded Swedish stocks, two hypot
This paper investigates the predictive ability of technical trading rules (TTRs) on the Swedish stock market. Eight variations of two common TTRs—the relative strength index (RSI) and the moving average convergence/ divergence (MACD)—are applied on the constituent stocks of the OMX Stockholm 30 from January 2014 to December 2023. To evaluate forecasting ability, an event study is conducted. Abnorm
This thesis investigates the potential of hydrogen fuel cell (HFC) technology as a sustainable alternative for regional rail transport within the framework of the EU-Rail Flagship Project 6. The thesis focuses on developing a hybrid powertrain model that incorporates both HFC and battery technologies, implementing a rule-based energy management strategy to assess fuel consumption and environmental
This work studied a metal fluoride transition state analogue (TSA) complex of β-phosphoglucomutase (βPGM), a phosphoryl transfer enzyme catalysing the interconversion of glucose-6-phosphate (G6P) and glucose-1-phosphate (G1P), and its P146A and A136N mutants using advanced NMR spectroscopy methods. Conformational exchange rates of βPGM:MgF3–:G6P TSA complex were extracted at a grid of temperatures
Utvecklingen av kriminella nätverk och deras rekrytering av barn i Sverige är och fortsätter vara en oroande utveckling. Rekryteringen utförs ofta av äldre barn, processen går ofta snabbt och yngre barn ses som billig arbetskraft som är lätt att manipulera till att begå olika typer av allvarliga brott. Dessa barn är ofta både offer och förövare på samma gång. För att hantera rekryteringen och att The development of criminal networks and its recruitment of children in Sweden over the last few years have been and continue to be a worrying development. The recruitment is often conducted by older children, it is often a short process, and younger children are seen as cheap labour who are easy to manipulate into committing a variety of different severe crimes. These children are often both vict
Preface Conference Paper Human Rights City Gwangju: Its Development, Achievement and Limitation Conference Paper Gwangju, 30 September to 3 October 2019 SHIN Gyonggu Gwangju International Center AHN Jean Chonnam National University Law School CHON Jinhee Lecturer, Chonnam National University Law School September 2019 RWI supported the above research through its capacity building programs worldwide
https://rwi.lu.se/wp-content/uploads/2021/06/Human-Rights-City-Gwangju-FINALR.pdf - 2026-07-17
The power systems of drilling rigs have changed considerably since the early days of steam driven machinery. This paper reviews that progression, from mechanical and diesel electric configurations through to modern hybrid and renewable integrated systems, with a focus on the power conversion technologies that enable each stage. Coverage includes the electrical architecture of drilling rig power sy
When the Swedish construction code (in 1994) allowed wooden multi-storey buildings to be built, this type of lightweight construction became popular due to its low cost and ease of construction, and also because wood is a plentiful resource in Sweden. Drawbacks in such buildings are disturbing vibrations and noise propagating in the construction, especially through junctions. In lightweight constr
Rangelia vitalii is a protozoon that causes diseases in dogs, and anemia is the most common laboratory finding. However, few studies on the biochemical changes in dogs infected with this protozoon exist. Thus, this study aimed to investigate the biochemical changes in dogs experimentally infected with R. vitalii, during the acute phase of the infection. For this study, 12 female dogs (aged 6-12 mo
The insulator-to-metal transition (IMT) in vanadium dioxide (VO2) can enable a variety of optics applications, including switching and modulation, optical limiting, and tuning of optical resonators. Despite the widespread interest in VO2 for optics, the wavelength-dependent optical properties across its IMT are scattered throughout the literature, are sometimes contradictory, and are not available
A microtitre plate based enzyme-linked immunosorbent assay for determining the concentration of serum amyloid A (SAA) is described. The method employs easily produced sequence-specific rabbit antibodies and the preferential absorption of SAA to polystyrene, which obviates the use of capture antibodies and allows an assay time of only 3.5 h, so that the diagnostic potential of the SAA level as a ra
Nitrous oxide (N2O), like carbon dioxide, is a long-lived greenhouse gas that accumulates in the atmosphere. Over the past 150 years, increasing atmospheric N2O concentrations have contributed to stratospheric ozone depletion1 and climate change2, with the current rate of increase estimated at 2 per cent per decade. Existing national inventories do not provide a full picture of N2O emissions, owin
