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This thesis is based on three scientific papers dealing with different models for coordinated control of multi-stage inventory systems. The ability to control multi-echelon inventory systems, is paramount for reducing tied up capital and inventory costs in large distribution systems. It is also one key issue in achieving efficient supply chain management. We focus our attention on a general distr
In a forest ecosystem at steady state, net carbon (C) assimilation by plants and C loss through soil and litter decomposition by heterotrophic organisms are balanced. However, a perturbation to the system, such as increased mean soil temperature, will lead to faster decay, enhancing CO2 release from decomposers, and thus upsetting the balance. Recent in situ experiments have indicated that the sti
Background: We were concerned that a fixed rather than a weight-based dosing regimen of dalteparin sodium to prevent venous thromboembolism. (VTE) might result in decreased efficacy in obese patients and decreased safety in elderly patients. Methods: We retrospectively performed subgroup analyses using the database from the Prospective Evaluation of Dalteparin Efficacy for Prevention of VTE in Imm
BACKGROUND: The purpose of this study was to analyze the impact of stent-graft design and operator skills on outcomes after endovascular abdominal aortic aneurysm repair. STUDY DESIGN: One hundred sixty-four patients (mean age 71 years) underwent stent-graft repair. Patients were treated with four different types of stent-graft: first-generation (n = 58) and second-generation (n = 17) Ivancev-Malm
Background: Computed tomography (CT) of the brain is performed with high local doses due to high demands on low contrast resolution. Advanced algorithms for noise reduction might be able to preserve critical image information when reducing radiation dose.PurposeTo evaluate the effect of advanced noise filtering on image quality in brain CT acquired with reduced radiation dose. Material and Method
OBJECTIVES: Meniscal pathology in which the aetiology is often unclear is a frequent finding on knee MRI. This study investigates potential risk factors for medial meniscal lesions or extrusion in middle-aged and elderly persons. METHODS: Prospective cohort study using population-based subjects from Birmingham, Alabama and Iowa City, Iowa, USA (the Multicenter Osteoarthritis Study). 644 men and
Popular Abstract in Swedish Hur näringsbehovet tillgodoses skiljer sig mellan spädbarn och småbarn. Bröstmjölk och/eller modersmjölksersättning dominerar som källor till energi-och näringsintag under första levnadsåret. I småbarnskosten däremot, tillför komjölk majoriteten av energi, protein och mättat fett, men knappast något järn eller fleromättat fett alls. Flera rekommendationer finns över hurIn the diet for young children, whole cow´s milk is the major contributor of calories, protein and saturated fat, but it supplies little iron and polyunsaturated fat. Although several recommendations exist for the composition of formula, recommendations for the composition of milk for young children are lacking. We investigated if milk with modified fat-, protein-, and iron content aimed at young
BACKGROUND:: While increased mortality in rheumatoid arthritis (RA) is well established there is conflicting evidence on the association between osteoarthritis (OA) and mortality. Our aim was to estimate all-cause mortality in Swedish patients with RA and OA compared with the general population. METHODS:: Cohort study of the population of Skåne region, Sweden (1.3 million), based on physicians’ di
Professional cycling combines extensive endurance training with non weight-bearing exercise, two factors often associated with lower bone mineral density (BMD). Therefore BMD was measured with dual-energy x-ray absorptiometry in 30 professional road cyclists (mean (SD) age: 29.1 (3.4) years; height: 178.5 (6.7) cm; weight: 71.3 (6.1) kg; %fat mass: 9.7 (3.2)%; (V) over dotO(2) max: 70.5 (5.5) ml .
Context Advanced, life-limiting illnesses are likely to have a predictable functional decline through a terminal phase to death, but some patients may also die suddenly. To date, empirical evidence characterizing “sudden death” in hospice/palliative care is lacking. Objectives The aim of this study was to determine prevalence and clinicodemographic predictors of sudden death in hospice/palliative
BACKGROUND AND AIM: Primary sclerosing cholangitis (PSC) is characterized by multiple strictures of the biliary tree. Patients with PSC frequently require repeated endoscopic retrograde cholangiopancreatography (ERCP) procedures. These procedures are encumbered by an increased incidence of infectious adverse events such as cholangitis. Evidence regarding whether antibiotic prophylaxis (AP) should
Background: Several studies have shown associations between cadmium (Cd) exposure and an increased risk of fractures. However, the size of the risk is still unclear and proper adjustment for smoking is a challenge. The aim of this study was to quantify the association between dietary cadmium measured in blood and fracture risk in the general Swedish population through a large population-based case
This article investigates and discusses a football chant, a riff from a popular rock song entitled “Seven Nation Army” by the rock group The White Stripes from Detroit, USA. The chant is sung by supporters at football matches even in Sweden but also in corresponding social contexts, as when high school students graduate or at the pub. The survey, which was to by a reduction method compare the riff
Popular Abstract in Swedish Varje år drabbas cirka 8000 svenska kvinnor av bröstcancer, och antalet nyinsjuknade ökar årligen med någon procent. I Sverige idag finns fler än 90 000 kvinnor som har avslutat eller är under behandling för sjukdomen. Med hjälp av nya återfallsförebyggande läkemedel har prognosen kraftigt förbättrats och 5-årsöverlevnaden är nästan 90 %. Den stora utmaningen i dagens bOne of the great challenges in breast cancer treatment today is to customize adjuvant treatment to each patient’s individual needs. To do this it is necessary to learn more about the prognostic and treatment predictive factors that determine the risk of relapse and response to a certain mode of treatment. This thesis describes studies on the effect of amplified in breast cancer 1 (AIB1), a coactiv
A dye-binding method using Acid Orange 12 was investigated regarding its suitability for the quantification of available lysine, as a means of monitoring the Maillard reaction in skim milk powders. The method was evaluated by analyzing a wide range of milk powders produced by three different drying methods and stored under various conditions. A pilot-scale freeze-dryer, spray-dryer and drum-dryer
A measurement of elastic deeply virtual Compton scattering gamma*p --> gamma p using e(+) p and e(-) p collision data recorded with the HI detector at HERA is presented. The analysed data sample corresponds to an integrated luminosity of 306 pb(-1), almost equally shared between both beam charges. The cross section is measured as a function of the virtuality Q(2) of the exchanged photon and the ce
Background & Aims: Assess the prevalence of peri-transplant heart failure and its potential relation to post-transplant morbidity and mortality. Methods: A retrospective study was performed on 234 consecutive cirrhotic patients undergoing liver transplantation in a single European center from 1999 to 2007 (mean age 52, 30% women, 36% with alcoholic liver disease, 24% with viral hepatitis, 18%
