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We measured the levels of cartilage proteoglycan (PG) fragments in knee joint synovial fluid obtained from patients with previous trauma of the knee, early gonarthrosis, or pyrophosphate synovitis, and in age-matched control subjects. During the initial 3-4 weeks after rupture of the anterior cruciate ligament or the meniscus (confirmed by arthroscopy), markedly increased PG fragment levels were f
Osteoarthritis does not deserve the term "degenerative joint disease", the course of the disease is characterized by dynamic changes in both synthesis and degradation of cartilage and other joint tissues. At the end stage all tissues of the joint are involved, not only the cartilage. In the early phases of the disease, changes in cartilage metabolism can be detected through assay of biomarkers in
Human glandular kallikrein 2 (hK2) is a serine protease expressed mainly by the prostate gland with 80% identity in primary structure to prostate specific antigen (PSA). hK2 has proven to be a useful marker of prostate cancer which can be used in combination with PSA to better discriminate between prostate cancer and benign prostate hyperplasia. The studies on hK2 have been hampered by its very lo
Rehabilitation exercises are essential for recovery from many injuries, and their practice is guided by physical therapists in order to avoid the risk of further damage. The physical therapists have limited tools for conducting a quantified assessment of movement quality and this study investigates whether machine learning could be used to improve that process. A way to assess movement is to analy
Den svenska straffprocessen bygger i dag på en i huvudsak ackusatorisk ordning, där åklagaren ansvarar för utredningen medan domstolen har det yttersta ansvaret för att pröva skuldfrågan och bestämma påföljd. Genom införandet av strafflindring enligt 29 kap. 5 a § BrB har incitament skapats för misstänkta att lämna uppgifter om både egen och annans brottslighet. Uppsatsen analyserar hur sådana uppThe Swedish criminal procedure is currently primarily accusatorial, in which the prosecutor is responsible for the investigation, while the court has the ultimate responsibility for determining guilt and imposing a sentence. The introduction of mitigation of a sentence under Chapter 29, Section 5a of the Swedish Penal Code has created incentives for the prosecuted person to provide information abo
This thesis examines how the Nordic Council constructs and employs narrative within its implementation of Agenda 2030 as a means of strengthening its ontological security and collective sense of self. This approach implies that security is not only a product of material protection rather also a product of interpretive coherence. The Agenda 2030 is treated as a tool that frames complex policy quest
Groundwater is considered one of the most valuable fresh water resources. The main objective of this study was to produce groundwater spring potential maps in the Koohrang Watershed, Chaharmahal-e-Bakhtiari Province, Iran, using three machine learning models: boosted regression tree (BRT), classification and regression tree (CART), and random forest (RF). Thirteen hydrological-geological-physiogra
The purpose of this paper was to discuss stigma and stigmatisation in relation to social policy and social work. By discussing welfare systems in social policy I wanted to see if there could be any connection between social policy and stigma. I used case studies of hearing impaired adults to give examples of how the stigma processes work. By connecting the stigma and the social policy theories wit
In one of six garbage collectors area in Cairo, Esbet el Nakhl, there's a handicap school run by the Coptic church. We chose to study this school using observations and interviews. The purpose of our thesis has been to describe the school, the goals of the education and the educational forms. The questions we asked our selves before the trip to Cairo were; how does the school look like? What&#
This research set out to examine if participation can improve the management of water resources in rural Jordanian communities. Jordan is second most resource-scare country in the world, and is facing significant increase in demand for water as a result of the arrivals of refugees from the Syrian conflict. The purpose of this work is to delineate the role of participation as a facilitator for impr
Uppsatsen behandlar konflikten mellan två inte sällan kolliderande intressen, vindkraft och rennäring. I ljuset av folkrättsliga instrument till skydd för urfolk, ska samernas rätt till mark och vatten skyddas. För samer är denna rätt en förutsättning för renskötselns bedrivande, som det samiska kulturarvet i stora delar bygger på. Rennäringen förutsätter stora markområden där renar fritt kan flytThis essay discusses the conflict between wind power and reindeer husbandry, two interests which at times collide. In light of international law and its instruments for the protection of indigenous peoples, the Samis’ rights to land and water shall be protected. The right to land is a prerequisite for the Samis to pursue their reindeer herding, which lays the foundation for the cultural heritage o
The EU’s recent regulatory approach in the digital sphere promises to introduce greater consideration for fundamental rights. However, this does not apply to all fundamental rights and their holders equally. With particular focus on the freedom to conduct a business, this article will be exploring the restrictions imposed on certain undertakings—so-called gatekeepers—operating in the Digital Singl
Resin adsorption is an effective technology for the fermentable sugar slurry detoxification in lignocellulosic biorefinery, but with the great limitation of the loss of resin capacity from inhibitor contamination and the extensive use of acid and base solutions for their regeneration. In this study, we developed a green and practical method with ultrasound assisting the depletion of poisoned resin
Tissue engineering strategies predominantly rely on the production of living substitutes, whereby implanted cells actively participate in the regenerative process. Beyond cost and delayed graft availability, the patient-specific performance of engineered tissues poses serious concerns on their clinical translation ability. A more exciting paradigm consists in exploiting cell-laid, engineered extra
OBJECTIVES: Opioid-free anesthesia (OFA) is a promising alternative to traditional opioid-based anesthesia. Research indicates that OFA reduces postoperative opioid consumption and related adverse effects while maintaining effective pain control and patient safety. Despite these benefits, clinical adoption of OFA remains limited, possible due to gaps in evidence. To bridge this knowledge gap, a we
In this forum, seven scholars discuss Oliver P. Richmond’s The Grand Design: The Evolution of the International Peace Architecture, published in 2022. The editors, Gëzim Visoka and Annika Björkdahl, contextualise the book’s contribution within the broader intellectual framework of Richmond’s thoughts and writings on peace in the context of International Relations. Roland Bleiker examines the book’
Background: Bioresorbable scaffolds have been associated with inferior outcomes compared to contemporary permanent metallic drug-eluting stents (DES) for percutaneous coronary intervention, particularly within the initial years after implantation; however, their long-term performance remains uncertain. This study aimed to evaluate the long-term outcomes of Swedish patients treated with Absorb bior
Godstransporter är en grundläggande förutsättning för samhällsekonomisk utveckling, näringslivets konkurrenskraft och tillgången till varor, men står samtidigt för en betydande andel av Sveriges växthusgasutsläpp. Att minska transporternas klimatpåverkan utan att hämma ekonomisk utveckling är därför en central utmaning. Ökad transporteffektivitet lyfts ofta fram som en nyckelstrategi, men dess potFreight transport is a fundamental prerequisite for socio-economic development, business competitiveness, and the availability of goods, while at the same time accounting for a substantial share of Sweden’s greenhouse gas emissions. Reducing the climate impact of transport without constraining economic development therefore constitutes a central challenge. Improved transport efficiency is often hi
A common methodology for analyzing metalworking fluid (MWF) aerosols in workplace air is based on gravimetry before and after organic solvent extraction of the MWFs from a suitable collection filter: Because MWFs have different chemical and physical properties, various mixtures of organic solvents have been used to extract the MWFs from their collection device. An alternative to organic solvents,
