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The aim of this study was to investigate whether there is an association between overexpression of cyclin D1 and response to therapy. Immunohistochemical overexpression of cyclin D1 was determined in paraffin-embedded specimens from diagnostic biopsies of 89 primary cases of squamous cell carcinoma of the head and neck (SCCHN), using a polyclonal antiserum. The tumor response rates were estimated
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The deregulation of the European transport market has been a controversial topic, characterised by a lack of facts and figures on the actual impact of the regulations. Given the crucial importance of road freight transportation to European society, and the lack of figures and control of foreign vehicles operating domestically in other countries, the purpose of this paper is to present a novel, inn
Popular Abstract in English “We are not free in this area.” This is what the iNduna, a traditional leader at KwaDapha, shared with me when we first met in August 2011. KwaDapha is a small rural community at Bhanga Nek, Kosi Bay, in northern KwaZulu-Natal/Maputaland – one of the most scenic areas on the South African coastline. Kosi Bay falls within the Coastal Forest Reserve section of the iSimaIn the past several decades under a growing influence of ecological modernisation, various assumed ‘win-win’ approaches to protected area conservation and poverty alleviation have been introduced all over the world, especially in resource-rich developing countries. Yet protected area conservation is an inherently political process, and the goals are often not achieved. There are concerns about com
The purpose of this work is the enhancement of performance by a new design of monolithic heat exchangers under steady-state operating conditions. Heat transfer phenomena and hydrodynamics have been studied and visualized by computational fluid dynamics (CFD). Further, a simple gas distribution system has been analyzed in purpose to find the best performance of the exchanger. To achieve this, 3D si
This study reports on a study from 2008 of overall mobility patterns among older people and the mobility patterns of those in transition from a two person household to a one person household. The purpose of the study was to explore the mobility patterns of those in transition from a two-person household to a one-person household in relation to the overall patterns of mobility of the older people.
In this article, the author discusses the implications of a 6+6-hour model for the production economy of the Finnish Company Essilor Oy. The theory of returns to scale has been used to analyse the results of the change from one 8-hour shift to the 6+6-hour-shift system. It is shown that the company Essilor attained a better production economy and increased profit by introducing a 6+6-hour-shift sy
This paper considers the potential contribution of Industrial Symbiosis (IS) networks in fostering environmental innovation at the local or regional level. Drawing on literature from innovation studies and innovation in spatial proximity, we outline three factors that are important for the innovation process and identify where the effects from IS networks can be explored. We use observations from
The fer gene from Bacillus subtilis has been subcloned and overexpressed in Escherichia coli and the protein (Fer) purified to homogeneity. N-Terminal sequencing and mass spectrometry indicate that the initiator methionine is removed from the protein and that the molecular mass is 8732 Da consistent with that deduced from the gene sequence. Amino-acid sequence comparisons indicate that Fer is a fe
BACKGROUND: The TT virus (TTV) is a newly identified blood-borne virus. Its association with disease is still unknown, and screening of blood donors has not been implemented. Several genotypes of the TTV have been identified. STUDY DESIGN AND METHODS: Three hundred seventy healthy blood donors were randomly selected and tested for TTV by the PCR method. Sequencing of a part of the genome was perfo
As a first application of optical double resonance and zero field level crossing spectroscopy to the elements of the sixth group in the periodic table of the atoms, the 5p36s5S2 level in the Te-I spectrum was investigated using natural tellurium in a high temperature quartz cell. For the electronic Landé-factor and the natural radiative lifetime the following values were obtained:$$g_J \left( {5p^
Det är angeläget, att det schematiska sätt, som nu normalt tillämpas för en dimensionering och utformning av en byggnads eller ett samhälles försvar, på sikt ersätts med ett mer kvalificerat förfarande, som bygger på funktionsbaserade analyser eller bedömningar av brandpåverkade systems reaktion för alternativa möjliga scenarier. Detta är huvudbudskapet i följande rapport, som beylser förutsättnin
The fragile histidine triad (FHIT) gene, located within chromosome arm 3p, is a potential target for testicular tumorigenesis. In the present study, 62 primary testicular germ cell tumors were analyzed for allelic imbalance (AI) at 10 loci mapping to chromosome bands 3p14.1-21.1. Twenty-seven tumors (44%) showed AI at one or more 3p loci. The chromosome 3 copy number was evaluated by fluorescence
Aims and objectives. This study aimed at investigating life satisfaction and its relation to living conditions, overall health, self-care capacity, feeling lonely, physical activities and financial resources among people (65+) with reduced self-care capacity. Background. Knowledge about factors related to low life satisfaction among older people with reduced self-care capacity is sparse, although
